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BP while on Tx 8 years 2 months ago #11623
Hi all I have been thinking about this quite a lot. I noticed that some members have reported high BP while on meds and this sometimes required immediate action. My resting BP is 140/96 atm and I have been sitting all day. Heart rate 83. I have read that there can be an interaction with the DAA's resulting in an extremely low heart rate but I don't know anything about high BP. Before Tx I was on BP meds. Since Tx I have had to add another medication for high BP. gt 1a VL 6m F2/3 FibroScan - 9KPa in 2011 and 7KPa in 2015 sof/dac 10 December for 12 weeks pre tx alt 85 ast 51 4 wk alt 34 ast 31 UND <35 8 wk alt 29 ast 32 UND <15 12wk alt 25 ast 25 EOT 3.3.16 SVR24 UND KPa5.3 F0 in normal range I am well .forever grateful to fixhepc | |
BP while on Tx 8 years 2 months ago #11632
| Hi Pat, There do seem to be a few with raised BP, some have been really high. Last check mine was up, but not dangerously, must get it checked again. It seems to me it's the girls who seem to suffer this more or are the boys just being quiet? Maybe it's something to do with lower body weight ? Hoping yours stays steady for you GT1a Dec14 F2/8.7 VL 900000-2.5M Jan16 Hepcivir-L MonkMed/Redemption Baseline: VL 913575 Alt 76 Platelets low Wk2 VL1157 Alt 23 DET Wk 8 VL 32 Alt19 'In the slow lane' June16 Fibro 5.7 F0/1 LIF 1.5 Wk 11 VL<12 Alt 13 Det/Unq Extending tx 12 wks Mylan Sofo/Dac MonkMed Wk 14 VL <12 Det/Unq Wk 16 VL UNDETECTED Wk 22 + 4 Wks Sunprevir FixHepC Wk 24 UNDETECTED Alt 13 Wk 12 post tx SVR12 Wk 26 SVR24 Thank-you Tim, Dr Debasis @ MonkMed & Dr Freeman @ Fix HepC The following user(s) said Thank You: pat1 |
BP while on Tx 8 years 2 months ago #11642
mine was 140/80 but on Harvoni it shot up to 186/95, 180/80 etc. so it does make the BP higher but NOT in all cases. Its now at around 150/85. I do take BP meds for long before DAA treatment Treatment naive F 3/4 Genotype 1 a & b V/L 17 MILLION Started Harvoni 11th Dec 2015 for 12 weeks 4 weeks VL UND 6 WEEKS ALT 32, AST 34 EOT 03/03 2016 ! UND ALT 34, AST 26 04.04.2016 SVR 4 26.05.2016 SVR 12 16.08.2016 SVR 24 | |
BP while on Tx 8 years 2 months ago #11654
Hi Pat, With suitable medication mine is usually maintained at about 110-120 over 70 something.....depending. Two weeks after I started Tx it had jumped to 150/90 which we monitored. It dropped back slowly over the next few weeks and by about 8 or 9 weeks was back to pretreatment levels. I don't know whether it was a side effect of the meds or just my emotional/physical response to everything that was happening to me (even the act of measuring your blood pressure can make it change if you are worried about the result Also, most people need a type and dose size of hypertension meds that is somewhat tailored to them along with time to adjust to the specific dose. That medication will most likely be metabolised at least partly by their liver, so it is possible that the suddenly more efficient liver is then metabolising the BP meds much quicker than it did before. So maybe a need for a higher dose, a different med or a period of adjustment? All speculation of course. Anyone with diagnosed hypertension should be monitoring regularly anyway but particularly on treatment and for others it doesn't hurt to get your Dr to check you while attending monitoring visits. G3a since '78 - Dx '12 - F4 (2xHCC) 24wk Tx - PEG/Riba/Dac 2013 relapsed 24wk Tx - Generic Sof/Dac/Riba 2015/16 relapsed 16wk Tx - 12/01/17 -> 03/05/17 NS3/NS5a + Generic Sof SVR7 - 22/06/17 UND SRV12 - 27/07/17 UND SVR24 - 26/10/17 UND | |
BP while on Tx 8 years 2 months ago #11660
I always had low BP, approximately 10 with 6. My GP doctor has checked my BP after starting tx. My BP increased a bit, now is about 13 with 8! Yes, something happened. I am curious about my BP after EOT. Wish you all the best HCV since I don't know. Diagnosed in 2010. GT1b, F0/F1, VL 9M, ALT 44, AST 42, Tx naive, started 12 wks Twinvir on 06.12.2015. Feeling great and grateful virus not detected 06.02.2016 & SVR24 This email address is being protected from spambots. You need JavaScript enabled to view it. | |
BP while on Tx 8 years 1 month ago #12452
Thanks for starting this important thread Pat1. I have had hypertension since peg/inf, but it was controlled at 120/80 with Atacand. The atacand is yellow flagged for sof/led, and a month prior to starting the DAAs my GP changed me to Coversyl 5, as I requested that I only be on all green flag medicines. I didn't want any mucking around on DAAs with any even slight contra-indications or timing issues. Around week 4 or so my BP shot up to a high of 220/120, and 180/130 varying during the consult. I was at my regular GP check up. I had as you may know had migraine as a sx during the first month of the DAA and that was about all, but the migraine was severe. I had noticed a night nausea increasing and an increase in the migraine three or four days prior to my consult which revealed the elevated BP. That was when I took a little rest from this forum but didn't blog my issue, I wanted to get good medical advice, up the meds as per my doctors prescription and be fresh to go again here. I am now fine and taking a diuretic BP med with an increase dose. I hope that people report their post tx experiences with this sx resolution. I watch my heart rate too, as I love sport. I climbed 400 steps as part of a walk I did yesterday at our coast here, and was careful not to overdo the climb. I still think my surfing is my best therapy sport wise, so long as I do not go too crazy after big waves and overdo the adrenaline while on tx. Walking is excellent. Good to know I wasn't the only one who had this experience. I was pretty surprised at such high readings given my non drinking non smoking and healthy lifestyle factors. My Gp referred to specialist type information in order to get the best fit meds as I am his first DAA patient. All going well now. Gen 1a Peg/inf/riba 2012(!) stop @ Wk 43 potassium low +issues (rlps week 4 post tx, VL120,000) scnds eg. adenomas. pre sof/led VL 240,000 Fibsc F0 Day 25 <30 Day 32 UND Week 10 UND EOT UND ALT11AST17GGT19 SVR4 UND ALT10 AST16 GGT13 SVR8 UND ALT <9 AST16 GGT15 SVR12 UND ALT14 AST19 GGT12 Bili 5 EOT +18 ALT13 AST20 GGT9 Bili 5 EOT +21 ALT11AST15 Cured SVR12 Dysplasia Adenomas RemvdAug '16 SVR24 UND ALT11AST16 ColonoscopyClear Nov17 LumpectomyClear ‘18 LithotripsyCytoscopyBiopsy 4/18 | |
BP while on Tx 8 years 1 month ago #12457
EOT back to 140/80 or lower Treatment naive F 3/4 Genotype 1 a & b V/L 17 MILLION Started Harvoni 11th Dec 2015 for 12 weeks 4 weeks VL UND 6 WEEKS ALT 32, AST 34 EOT 03/03 2016 ! UND ALT 34, AST 26 04.04.2016 SVR 4 26.05.2016 SVR 12 16.08.2016 SVR 24 | |
BP while on Tx 8 years 1 month ago #12461
Hi , Thanks also pat for starting this important thread, sorry haven't replied earlier. Have had bp issues like Ariel, which got a lot worse when I changed bp meds when already into tx. It spiked all over the place and finally ended up rising uncontrollably one evening to around 221 over 128. In fact I think the last reading may have been higher than this but can't find the bit of paper I wrote it down on. Luckily I had some of my old bp meds in the house and dr Debasis (wonderful man) guided me to taking them to bring it down. It had to be done carefully as I had two bp meds in my system at that point and he didn't want it dropping too much the other way. I was remaining calm, resting, stroking my dog etc but it just kept going up! Finally reached a tipping point and came down. I went back on my old meds at an increased dose, my dr agreed to this and the hospital concurred even though they had originally reduced the dose due to contraindication. I take it two hours after my hep meds and try to not let it get to after 11am on dr Debasis s advice. I have had a good response so far to the hep meds and hope this continues! I still have slightly high bp but fairly stable and as I only have one bottle of hep meds to go, hope it will settle back down after EOT. I'm pretty sure it's not a good idea to change bp meds whilst on tx., possibly o.k to add to them, maybe dr F can clarify? I just worry other people might end up in a similar situation as me and Ariel. Some bp meds take weeks to kick in fully, my new one definitely "didn't agree." Just wanted to post my experience for the record, feedback etc. Cheers Deb x Geno 1a, F1, tx naive, had it 35 yrs. Started Cipla HepcvirL on 12/01/16 Starting VL 490,000 At 16 days in <15 4 week results: UND 8 week results: UND 5 weeks EOT alt 25 SVR 15 - Not Detected 6 months EOT - Not Detected | |
BP while on Tx 8 years 1 month ago #12464
Mine has been jumping around quite a bit on tx as well. I have a BP monitor at home and it I could sit there for 10 minutes taking it constantly and it will give a different answer each time. Mostly varying on the systolic side (left number). Not so much as to worry me, but still curios. I would say normal for me t the moment is 145/85. Sometimes goes up to 155/90 or down to 107/72. All within minutes of each other. One pill left until EOT. Can't wait! HCV 35 yrs G1a F3 Tx naive started Lesovir-C 15/12/2015 pre tx: VL 5,250,000 ALT 374 AST 208 FIBROSCORE 10.4 4 weeks tx ALT 29/ AST 33. VL < 12 UI/mL 8 weeks tx ALT 29/ AST 34. VL UND 4 weeks after tx UND. SVR4. ALT 24/AST 18 | |
BP while on Tx 8 years 1 month ago #12465
Yes, I think my machines instructions said wait 3 mins between readings. But I don't check as much now. Also there is a memory function on my machine but I didn't use it, found it easier to write it down and compare. I know what you mean Ken, can't wait either! Congrats for tomorrow's EOT! Deb Geno 1a, F1, tx naive, had it 35 yrs. Started Cipla HepcvirL on 12/01/16 Starting VL 490,000 At 16 days in <15 4 week results: UND 8 week results: UND 5 weeks EOT alt 25 SVR 15 - Not Detected 6 months EOT - Not Detected The following user(s) said Thank You: pat1 | |
BP while on Tx 8 years 1 month ago #12497
Hi LG, "There do seem to be a few with raised BP, some have been really high. Last check mine was up, but not dangerously, must get it checked again. It seems to me it's the girls who seem to suffer this more or are the boys just being quiet? Maybe it's something to do with lower body weight ?" Mine crept up a bit following commencement of treatment and I suspect that a lot of males may be in this category?? Just needed some extra Atacand (checked interactions with DAA's) and some monitoring a week or so later and things okay. I will know for sure when I finish the DAA's and plan to ask to halve the Atacand and let the general practitioner see what happens. The surgery I go to is a bit old school and there is always a cuff from the gizmo that measures BP ready to jump on your arm when ever you enter the door. It is also good to see the percentage chances of having a heart attack reduce on that online calculator they use. Yours J. GT3a 1990 Failed Inter 1998, comb in 2000. HCC 2012 Started 24/52 Sof/Dac 27th October 2015. 1. Bloods 2 October 2015: AST - 165 (20-40), ALT - 265 (5-40), GGT 189 (5-50) 2, Bloods 20 November 2015: ALT etc normal; VL 19 3. Bloods 8 January 2016: AST - 40, ALT - 59, GGT 48 VL RNA UND 4. EOT 12 April 2016 - blood tests: all is well, CT scan: okay 5. AFP 11 June 2016: 4 ref< 11 6. VL July 2016: DET 7. Oct16 start treat - June17 UND 8. Jun 18, lfts okay, platelets a bit low. | |
BP while on Tx 8 years 1 month ago #12579
That's a shame I had an interesting short video describing BP - it explains things in nice simple terms. But link isn't working??? It certainly is scary to see how high some of you have been because my local GP won't monitor me I have no idea what my BP has been during Tx. I'm really wishing you all well and hope your Dr's can keep it under control because just knowing it's too high is added stress, thinking of you guys This: This: https://www.youtube.com/watch?v=Ab9OZsDECZw does work. Go figure.... QLD Australia ☀️ G3a HCV 35 yrs Tx naive Started Sof/Dac 13/01/16 Dec '15 AST 70 ALT 89 GGT 124 Fibroscore 8.5 F1-F2 13 Feb'16 VL UND AST 24 ALT 26 GGT 50H | |
BP while on Tx 8 years 1 month ago #12581
This is the link to the video I mentioned but it won't work in 'Video - Insert Video' ??? I click on Video icon at the top of here and at the bottom paste video link and click 'Insert Video' - am I doing it right? QLD Australia ☀️ G3a HCV 35 yrs Tx naive Started Sof/Dac 13/01/16 Dec '15 AST 70 ALT 89 GGT 124 Fibroscore 8.5 F1-F2 13 Feb'16 VL UND AST 24 ALT 26 GGT 50H | |
BP while on Tx 8 years 1 month ago #12582
| I had mine tested here at work a couple of weeks ago and it was 180/103!! I have one of those digital BP machines at home and it reads around 163/100 most of the time on my right arm and around 143/90 on my left arm, all over the place. I have never suffered with high blood pressure but it was actually how the Hep C was picked up. Very high at my annual health assessment at work last year so Doc followed on with blood tests etc. and here I am. Anyway my GP is not a great believer in the digital BP machines. It always reads high on his but when he takes it the old fashioned way it is always lower. It is something that I will need to address though and will be seeing my GP next week about it. I have no symptoms i.e. headaches etc. and feel well since finishing treatment. I have stopped using the BP monitor because it stresses me out Lives in Bendigo, Victoria No prior treatment Genotype 1b Fibroscan 0 (only showed a bit of a fatty liver) Diagnosed in February 2015 Currently on my last week of treatment taking led/sof Last LFT normal Insomnia the only side effect Undetected at 4 weeks SVR4 - undetected - all bloods good and GP very happy SVR12 bloods to be done at end of April 2016 SVR12 - undetected!!! |
BP while on Tx 8 years 1 month ago #12584
| Had a stroke 4 years ago & my doctor put me on blood pressure lowering meds. When I started taking HARVONI & RIBA, 20 weeks ago, my blood pressure started to drop. Since halving my blood pressure meds, I've been regularly sitting around 115 / 70 AUSTRALIAN HCV Genotype 1a 2003 Relapsed Peg Interferon / Ribavirin Pre treatment VL 2,000,000 ALT 65, AST 42, ALP 111, GGT 56 Bridging F3-4 Treatment -24 weeks - Sof , Led with 12 weeks Riba. 4 weeks VL <12 Detected ALP 89 , GGT 21 , ALT 17 , AST14 12 weeks VL Undetected ALP 96, GGT 22, ALT 20, AST 20 24 weeks VL Undetected ALP 83, GGT 20, ALT 21, AST 14 EOT 6th April 2016 SVR 5 weeks VL Undetected ALP 81, GGT 31, ALT 22, AST 20 The following user(s) said Thank You: Ariel |
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