Welcome, Guest |
TOPIC:
First Genotype 6 - Subtype 6a on this forum 7 years 10 months ago #18613
Hi Dac Good to hear that you are still UNDETECTED at 12 weeks. I would be hesitant to drop the Rib considering the Hepcivir L + Rib combination is working so well. I’m not a medical professional, so my opinion is merely a lay person using logic. Sorry to hear about your dose of diarrhoea and the itchy rash. I would be seeking out remedies for those instead. A discussion of remedies for rashes can be found here: fixhepc.com/forum/end-of-treatment-eot/7...sh.html?limitstart=0 fixhepc.com/forum/end-of-treatment-eot/6....html?start=15#14690 I’m sure others can suggest remedies for the diarrhoea. Ribavirin has a long list of side effects, however, try to look at it as short-term pain for a long-term gain. Cheers GT2 1983: Hospitalised with Acute non-A, non-B Hepatitis after ICU blood transfusion 3mths earlier => HCV GT2 22/02/16: (pre-tmt) ALT 61, VL 2.48 IU/ml Hepascore 0.32 (F1/2), fatigue, brain fog, bloating (Treatment Naïve) 10/04/16: (Start tmt) Sofovir +DaclaHep (SOF + DCV) by Hetero Labs in India 09/05/16: ALT 34, VL: NOT Detected 17/6/16 FBG 5.7; PPBG (@14.22) 6.9 (@ 20.45) 7.1; BP 124/72 | |
First Genotype 6 - Subtype 6a on this forum 7 years 10 months ago #18615
With so little really known about GT6 (as in only 25 people reported taking it for 24/25) it's really hard to take a view. If it ain't broke don't fix it but if it's coming to a question of stopping the riba or stopping treatment stop the riba and continue on the generic Harvoni. Trials Data For Genotype 6 Sofosbuvir PegIFN-α Ribavirin NAIVE default: svr: 100%, trials: NEUTRINO 100% GT6 (6/6) w24: svr: 100%, trials: ATOMIC 100% GT6 (5/5) Sofosbuvir Ledipasvir NAIVE default: svr: 96%, trials: NCT01826981 96% GT6 (24/25) Sofosbuvir Daclatasvir NAIVE default: svr: 97%, trials: No Trials - Based on GT1 extrapolation YMMV | |
First Genotype 6 - Subtype 6a on this forum 7 years 10 months ago #18621
Thank you Dr Freeman. Just met my hepatologist, she told me to continue taking Riba as my fibroscan is still f4 ? And have blood test at 16 weeks... GT-6a, diagnosed '08, relapsed after 78 weeks Tx PEG/Riba -Fibroscan '14 (F3/F4), Ultrasound with borderline cirrhosis without nodules, still compensated. Post re-Tx: VL: 10,100,000 IU/ml - PLT:120 - GGT: 43.42 - AST: 67.80 - ALT: 63.32 - Fibroscan: F4. Start Hepcivir L+Rib 24 weeks on April 2nd '16. Day 12: VL 567 IU/ml GGT 33 AST 32 ALT 30 Day 24: VL 29 IU/m GGT 28 AST 26 ALT 24 Day 56: VL UND GGT 27 AST 28 ALT 37 Day 84: VL UND GGT 30, AST 28, ALT 33, AFP 5.14 | |
First Genotype 6 - Subtype 6a on this forum 7 years 10 months ago #18623
1983: Hospitalised with Acute non-A, non-B Hepatitis after ICU blood transfusion 3mths earlier => HCV GT2 22/02/16: (pre-tmt) ALT 61, VL 2.48 IU/ml Hepascore 0.32 (F1/2), fatigue, brain fog, bloating (Treatment Naïve) 10/04/16: (Start tmt) Sofovir +DaclaHep (SOF + DCV) by Hetero Labs in India 09/05/16: ALT 34, VL: NOT Detected 17/6/16 FBG 5.7; PPBG (@14.22) 6.9 (@ 20.45) 7.1; BP 124/72 | |
First Genotype 6 - Subtype 6a on this forum 7 years 10 months ago #18632
| GT1a; Got it some time in the 70's; Diagnosed @1976 Tx naive METAVIR: A2-F2 SOT May 18, 2016: CMP: AST 162 ALT 241 VL 13000000 3 weeks after SOT: AST 27 ALT 31 VL 138 Reached EOT Aug. 10, 2016 / Received svr4 results Sept. 20, 2016: AST 22 ALT 24 Hep C RNA "NOT DETECTED" AS OF 3/20/2017 ,Hep C RNA PCR "NOT DETECTED" THAT'S SVR24! |
First Genotype 6 - Subtype 6a on this forum 7 years 10 months ago #18671
Thanks Matt, wish the best for you too GT-6a, diagnosed '08, relapsed after 78 weeks Tx PEG/Riba -Fibroscan '14 (F3/F4), Ultrasound with borderline cirrhosis without nodules, still compensated. Post re-Tx: VL: 10,100,000 IU/ml - PLT:120 - GGT: 43.42 - AST: 67.80 - ALT: 63.32 - Fibroscan: F4. Start Hepcivir L+Rib 24 weeks on April 2nd '16. Day 12: VL 567 IU/ml GGT 33 AST 32 ALT 30 Day 24: VL 29 IU/m GGT 28 AST 26 ALT 24 Day 56: VL UND GGT 27 AST 28 ALT 37 Day 84: VL UND GGT 30, AST 28, ALT 33, AFP 5.14 The following user(s) said Thank You: Matt-Kenney-google, fitz | |
Time to create page: 0.258 seconds