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GT2 Honks About Generic Sofosbuvir +Daclatasvir (SOF + DCV) 7 years 11 months ago #16343
Hi Everyone Great News Today … I finally got back by week 4 Vial Load Test. All of my week 4 tests results are back now. I was thrown a curve ball initially with an unexpected high fasting glucose level. It concerned me and I was worried it may have adverse effects on the efficacy of the SOF + DCV. I was feeling confident prior to this. I was also feeling the pressure of not letting the GT2 team down …especially considering that I had the audacity to call myself GT2 and Dr Freeman stated that he has 100% for SOF + DCV in GT2 so far. fixhepc.com/forum/gt2/1000-2b-juen-start...ndetected.html#16057 Anyway, I can happily say that I haven’t ruined the batting average. Dr Freeman, you still have a perfect strike rate. I know I’m only on first base, but I’m confident of making it home to SVR12. Thanks Greg Jefferys for taking the time to explain all of my treatment options, considering your busy schedule at the time, and then making the rest of the process a breeze. I will always be internally grateful to you and Dr Freeman. This has changed my life! 1983: Hospitalised with Acute non-A, non-B Hepatitis after ICU blood transfusion 3mths earlier => HCV GT2 22/02/16: (pre-tmt) ALT 61, VL 2.48 IU/ml Hepascore 0.32 (F1/2), fatigue, brain fog, bloating (Treatment Naïve) 10/04/16: (Start tmt) Sofovir +DaclaHep (SOF + DCV) by Hetero Labs in India 09/05/16: ALT 34, VL: NOT Detected 17/6/16 FBG 5.7; PPBG (@14.22) 6.9 (@ 20.45) 7.1; BP 124/72 | |
GT2 Honks About Generic Sofosbuvir +Daclatasvir (SOF + DCV) 7 years 11 months ago #16345
Sorry about the Freudian Slip I will always be internally grateful I meant, that I will always be eternally grateful ... My internal liver will also be forever indebted to you guys ... 1983: Hospitalised with Acute non-A, non-B Hepatitis after ICU blood transfusion 3mths earlier => HCV GT2 22/02/16: (pre-tmt) ALT 61, VL 2.48 IU/ml Hepascore 0.32 (F1/2), fatigue, brain fog, bloating (Treatment Naïve) 10/04/16: (Start tmt) Sofovir +DaclaHep (SOF + DCV) by Hetero Labs in India 09/05/16: ALT 34, VL: NOT Detected 17/6/16 FBG 5.7; PPBG (@14.22) 6.9 (@ 20.45) 7.1; BP 124/72 | |
GT2 Honks About Generic Sofosbuvir +Daclatasvir (SOF + DCV) 7 years 11 months ago #16346
Excellent news, GT2. It's good to see your vial load is empty now Genotype 1a Diagnosed in 2004, had HCV for all my adult life. Until 2016!!!! Harvoni treatment, started 19 March 2016 4 week results Bilirubin 12 down from 14 pre treatment, Gamma 25 down from 52, ALT 19 down from 63, AST 19 down from 47, VL <15 down from a lazy 6 million or so EOT Results Bilirubin 10, GGT 18, ALT 19, AST 21, VL UND 12 Weeks post EOT Bilirubin 11, GGT 16, ALT 22, AST 20, VL UND Cured baby | |
GT2 Honks About Generic Sofosbuvir +Daclatasvir (SOF + DCV) 7 years 11 months ago #16353
Hope this next doesn't offend anyone... Genotype 1a Diagnosed in 2004, had HCV for all my adult life. Until 2016!!!! Harvoni treatment, started 19 March 2016 4 week results Bilirubin 12 down from 14 pre treatment, Gamma 25 down from 52, ALT 19 down from 63, AST 19 down from 47, VL <15 down from a lazy 6 million or so EOT Results Bilirubin 10, GGT 18, ALT 19, AST 21, VL UND 12 Weeks post EOT Bilirubin 11, GGT 16, ALT 22, AST 20, VL UND Cured baby | |
GT2 Honks About Generic Sofosbuvir +Daclatasvir (SOF + DCV) 7 years 11 months ago #16358
1983: Hospitalised with Acute non-A, non-B Hepatitis after ICU blood transfusion 3mths earlier => HCV GT2 22/02/16: (pre-tmt) ALT 61, VL 2.48 IU/ml Hepascore 0.32 (F1/2), fatigue, brain fog, bloating (Treatment Naïve) 10/04/16: (Start tmt) Sofovir +DaclaHep (SOF + DCV) by Hetero Labs in India 09/05/16: ALT 34, VL: NOT Detected 17/6/16 FBG 5.7; PPBG (@14.22) 6.9 (@ 20.45) 7.1; BP 124/72 | |
GT2 Honks About Generic Sofosbuvir +Daclatasvir (SOF + DCV) 7 years 11 months ago #16362
Metaphors be with you!! mike This email address is being protected from spambots. You need JavaScript enabled to view it. forums.delphiforums.com/generichcvtx G 1a F-1 Started tx 10/23/15 (Meso sof & led) ALT 48 AST 28 v/l 1.6 mil 11/17/15 4 wk lab ALT 17 AST 16 <15 11/18/15 Started Harvoni 12/16/15 8 wk lab ALT: 15 AST: 13 V/l UND 1/14/16 Fin. Tx 7/07/16 UND SVR 24 | |
GT2 Honks About Generic Sofosbuvir +Daclatasvir (SOF + DCV) 7 years 11 months ago #16366
| GT1a; Got it some time in the 70's; Diagnosed @1976 Tx naive METAVIR: A2-F2 SOT May 18, 2016: CMP: AST 162 ALT 241 VL 13000000 3 weeks after SOT: AST 27 ALT 31 VL 138 Reached EOT Aug. 10, 2016 / Received svr4 results Sept. 20, 2016: AST 22 ALT 24 Hep C RNA "NOT DETECTED" AS OF 3/20/2017 ,Hep C RNA PCR "NOT DETECTED" THAT'S SVR24! |
GT2 Honks About Generic Sofosbuvir +Daclatasvir (SOF + DCV) 7 years 11 months ago #16367
| GT1a; Got it some time in the 70's; Diagnosed @1976 Tx naive METAVIR: A2-F2 SOT May 18, 2016: CMP: AST 162 ALT 241 VL 13000000 3 weeks after SOT: AST 27 ALT 31 VL 138 Reached EOT Aug. 10, 2016 / Received svr4 results Sept. 20, 2016: AST 22 ALT 24 Hep C RNA "NOT DETECTED" AS OF 3/20/2017 ,Hep C RNA PCR "NOT DETECTED" THAT'S SVR24! |
GT2 Honks About Generic Sofosbuvir +Daclatasvir (SOF + DCV) 7 years 11 months ago #16369
Congrats GT2 GT2b diagnosed 10/2015 since: unknown 11/20/15 VL= 214,070 12/4/15 ALT=18 AST= 24 1/16/16 started sof/dac 2/13/16 @4wks VL=UND ALT=13 AST=22 3/12/16 @8wks VL=UND ALT=10 AST=18 4/9/16 EOT VL=UND ALT=11 AST=19 9/23/16 SVR24 ALT=11 AST=22 The following user(s) said Thank You: Matt-Kenney-google, GT2 | |
GT2 Honks About Generic Sofosbuvir +Daclatasvir (SOF + DCV) 7 years 11 months ago #16380
FANTASTIC NEWS GT2! HONK HONK! NSW Australia. Genotype 1b 30+ years, F0-F1, VL 91,000 Feb 2015 (740,000 in 2010), Tx naive. Ordered Sof/Dac from Buyers Club 21 Sept, received 14 Oct. Virus UNDETECTED at 3 weeks AND 12 weeks (EOT) AND SVR4 AND SVR12 AND SVR24. A thousand thankyous to Dr James and the amazing FixHepC team. The following user(s) said Thank You: Matt-Kenney-google, GT2 | |
GT2 Honks About Generic Sofosbuvir +Daclatasvir (SOF + DCV) 7 years 11 months ago #16386
Thanks Agent 86. I was initially given the old curve ball trick 1983: Hospitalised with Acute non-A, non-B Hepatitis after ICU blood transfusion 3mths earlier => HCV GT2 22/02/16: (pre-tmt) ALT 61, VL 2.48 IU/ml Hepascore 0.32 (F1/2), fatigue, brain fog, bloating (Treatment Naïve) 10/04/16: (Start tmt) Sofovir +DaclaHep (SOF + DCV) by Hetero Labs in India 09/05/16: ALT 34, VL: NOT Detected 17/6/16 FBG 5.7; PPBG (@14.22) 6.9 (@ 20.45) 7.1; BP 124/72 The following user(s) said Thank You: Matt-Kenney-google | |
GT2 Honks About Generic Sofosbuvir +Daclatasvir (SOF + DCV) 7 years 11 months ago #16387
Hi Matt Great cartoon! Sometimes our so called “democracy” feels like a dictatorship … especially when the tail wags the dog to such an extent that big Phama dictates to governments and then avoids paying its fair share of corporate tax by funnelling the majority of their profits into low taxed countries, like Ireland (12.5%). I hope that you are sailing through your first few days of treatment. Best Wishes GT2 1983: Hospitalised with Acute non-A, non-B Hepatitis after ICU blood transfusion 3mths earlier => HCV GT2 22/02/16: (pre-tmt) ALT 61, VL 2.48 IU/ml Hepascore 0.32 (F1/2), fatigue, brain fog, bloating (Treatment Naïve) 10/04/16: (Start tmt) Sofovir +DaclaHep (SOF + DCV) by Hetero Labs in India 09/05/16: ALT 34, VL: NOT Detected 17/6/16 FBG 5.7; PPBG (@14.22) 6.9 (@ 20.45) 7.1; BP 124/72 | |
GT2 Honks About Generic Sofosbuvir +Daclatasvir (SOF + DCV) 7 years 11 months ago #16388
Hi CC2B I have to thank you from the bottom of my heart, and the other GT2s on this forum who have taken SOF + DCV, for giving me the confidence to step up to the plate and have an almighty swing at this difficult to hit HCV virus. I noticed that you, and the others, hit it well out of the park first time and every time. Based on that, I decided to join your team (sorry about the self invite ...) If it wasn't for you guys, like a blind fool, I would have followed the standard GT2 recommendation of SOF + RBA and probably been sick as a dog for 3 months or so. I really think that the “experts” who make these recommendations need to urgently reconsider their GT2 guidance. I really don’t deserve being promoted up the batting order … I’m just happy backing up all the GT2s before me … I’m merely standing on the shoulders of giants. Thanks guys! Cheers GT2 1983: Hospitalised with Acute non-A, non-B Hepatitis after ICU blood transfusion 3mths earlier => HCV GT2 22/02/16: (pre-tmt) ALT 61, VL 2.48 IU/ml Hepascore 0.32 (F1/2), fatigue, brain fog, bloating (Treatment Naïve) 10/04/16: (Start tmt) Sofovir +DaclaHep (SOF + DCV) by Hetero Labs in India 09/05/16: ALT 34, VL: NOT Detected 17/6/16 FBG 5.7; PPBG (@14.22) 6.9 (@ 20.45) 7.1; BP 124/72 The following user(s) said Thank You: CC2B | |
GT2 Honks About Generic Sofosbuvir +Daclatasvir (SOF + DCV) 7 years 11 months ago #16389
Hi Joy Thanks for Honking. Here’s a good old fashioned Aussie TOOT! TOOT! back. To paraphrase the Wriggles, Toot Toot, Chugga Chugga from the Big Red Car … Best Wishes GT2 1983: Hospitalised with Acute non-A, non-B Hepatitis after ICU blood transfusion 3mths earlier => HCV GT2 22/02/16: (pre-tmt) ALT 61, VL 2.48 IU/ml Hepascore 0.32 (F1/2), fatigue, brain fog, bloating (Treatment Naïve) 10/04/16: (Start tmt) Sofovir +DaclaHep (SOF + DCV) by Hetero Labs in India 09/05/16: ALT 34, VL: NOT Detected 17/6/16 FBG 5.7; PPBG (@14.22) 6.9 (@ 20.45) 7.1; BP 124/72 | |
GT2 Honks About Generic Sofosbuvir +Daclatasvir (SOF + DCV) 7 years 11 months ago #16390
1983: Hospitalised with Acute non-A, non-B Hepatitis after ICU blood transfusion 3mths earlier => HCV GT2 22/02/16: (pre-tmt) ALT 61, VL 2.48 IU/ml Hepascore 0.32 (F1/2), fatigue, brain fog, bloating (Treatment Naïve) 10/04/16: (Start tmt) Sofovir +DaclaHep (SOF + DCV) by Hetero Labs in India 09/05/16: ALT 34, VL: NOT Detected 17/6/16 FBG 5.7; PPBG (@14.22) 6.9 (@ 20.45) 7.1; BP 124/72 The following user(s) said Thank You: Ariel | |