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Daklinza/Sovaldi- side-effects and treatment duration 7 years 10 hours ago #24299
| So am I reading this right youre g-3 f-04 and were treated 2x then december 2017 treated a 3rd time and youre svr? If so I'm curious what the trial you were involved in? was G/P? glecaprivir/pibrentasvir? |
Daklinza/Sovaldi- side-effects and treatment duration 6 years 11 months ago #24303
Hi. It's time to update my situation for reference to future readers. I treated for 16 weeks with Daklinza/Sovaldi. I elected to wait until the 3 month post treatment mark for testing, as my then-side effects began subsiding somewhat. Results came back a week ago and I received good news- I am non-detectable for HCV 3. I will get a final test done next year to give full peace of mind, although I am aware current standing is to take the 3 mth post test as virtually final. My remaining treatment side effects include some neuropathy to hands/feet, some tiredness/mild fatigue and at times a flat mood. I was Genotype 3a with F1, treatment experienced (Pegasus/Ribavirin). Best of luck to all. X | |
Daklinza/Sovaldi- side-effects and treatment duration 6 years 11 months ago #24304
Congratulations on being SVR12, that's great news. Waiting until next year for your final test may be going a bit far. SVR24 is the big one that most of us on this forum are trying to reach.That 24 week post-treatment result should provide you with the certainty you are seeking. In the meantime I hope you can get some good advice about how to deal with your lingering issues. Best wishes! G2, infected maybe in 1971? Diagnosed HVnon-A non-B 1980s, revised to HVC 1990's. Treatment naive. Fibroscan & bloods all normal ranges. Viral load 7million, began Redemption trial4, 12-week generic Sof/Vel (Incepta) 2017. Week 4 UND, Week 12UND, SVR24 Thank-yous to my doctor for the script, to Jan at FixHepC for wrangling, and to Dr Freeman for courage. Kia kaha e hoa ma! | |
Daklinza/Sovaldi- side-effects and treatment duration 6 years 11 months ago #24306
Hello AK123, Congrats on the SVR12. Glad you did 16 weeks - it's clearly better for GT3s. With the neuropathy please get checked for diabetes and thyroid function. Some B complex vitamins may well do no good but may help and won't do any harm. YMMV | |
Daklinza/Sovaldi- side-effects and treatment duration 6 years 11 months ago #24329
| Well, I am only ten days after treatment virus free from tests and I am also feeling progressively worse with chronic fatigue, a flat mood/mild depression, unsatisfying sleep (ie waking exhausted) . as some time has elapsed how are you feeling now? The following user(s) said Thank You: coral |
Daklinza/Sovaldi- side-effects and treatment duration 6 years 11 months ago #24403
That is awesome!!! That gives me hope. I am genotype 3A and am going to o this trial | |
Daklinza/Sovaldi- side-effects and treatment duration 6 years 8 months ago #25085
SVR24- and straight back into full-time employment after a horrendous decade of HCV/interferon hell and accompanying poverty! | |
Daklinza/Sovaldi- side-effects and treatment duration 6 years 8 months ago #25087
Congratulations AK123! G3a since '78 - Dx '12 - F4 (2xHCC) 24wk Tx - PEG/Riba/Dac 2013 relapsed 24wk Tx - Generic Sof/Dac/Riba 2015/16 relapsed 16wk Tx - 12/01/17 -> 03/05/17 NS3/NS5a + Generic Sof SVR7 - 22/06/17 UND SRV12 - 27/07/17 UND SVR24 - 26/10/17 UND The following user(s) said Thank You: DrJames | |
Daklinza/Sovaldi- side-effects and treatment duration 6 years 8 months ago #25098
Such a good news story. Congratulations AK123 G1a probably early 1980's, Biopsy F1(2010), F2-F3(2015). VL 5+mill; 2+mill (2014) Tx naive. Accessed Sof/Led through Dr Freeman at GP2U and Buyers Club (lifesavers!!!) Commenced tx 12/11/15. 9 wk: VL <15 Detected but LFT = Normal 12 week results: UND (Yay!) Due to slow response commenced Sof/Dac 4 Feb for 12 weeks. EOT @ 24 weeks 27 April 2016. (With thanks to Dr Freeman et al). SVR11 result: VL 1,950,000. It's back! New tx 030916 (Viekira Pak, Solvadi, Ribavirin UND @ 111116. EOT 170217. SVR12 and SVR 24 | |
Daklinza/Sovaldi- side-effects and treatment duration 6 years 8 months ago #25152
Hi Gaj, been busy being cured and all and just come back on the forum for a look and noticed your signature: SRV12 - 27/07/17 UND!!! Could not have come across better news - cheers and well done! Jeff GT3a 1990 Failed Inter 1998, comb in 2000. HCC 2012 Started 24/52 Sof/Dac 27th October 2015. 1. Bloods 2 October 2015: AST - 165 (20-40), ALT - 265 (5-40), GGT 189 (5-50) 2, Bloods 20 November 2015: ALT etc normal; VL 19 3. Bloods 8 January 2016: AST - 40, ALT - 59, GGT 48 VL RNA UND 4. EOT 12 April 2016 - blood tests: all is well, CT scan: okay 5. AFP 11 June 2016: 4 ref< 11 6. VL July 2016: DET 7. Oct16 start treat - June17 UND 8. Jun 18, lfts okay, platelets a bit low. | |
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