emo Generics Late Breaker Accepted for EASL in April

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6 years 4 months ago #14244

#woohoo!

#duck wonderful news on your SVR12 Joy #flower
awesome #love


gt 1a VL 6m
F2/3 FibroScan - 9KPa in 2011 and 7KPa in 2015
sof/dac 10 December for 12 weeks
pre tx alt 85 ast 51
4 wk alt 34 ast 31 UND <35
8 wk alt 29 ast 32 UND <15
12wk alt 25 ast 25 EOT 3.3.16
SVR24 UND KPa5.3 F0 in normal range
I am well
.forever grateful to fixhepc
Last Edit: 6 years 4 months ago by pat1.
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6 years 4 months ago #14262

Great news Joy!


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SVR 24
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6 years 4 months ago #14284

I LOVE that I logged in and found all this happiness...Massive congratulations to you Joy for SVR12, and to Pat and Jaz for SVR4...what a wonderful read. The site is beginning to have more and more of these fantastic results coming through I love being in this good company. Yay! Onwards and no more HepC :+1: :+1: :+1: :evil: #love


Gen 1a
Peg/inf/riba 2012(!) stop @ Wk 43 potassium low +issues (rlps week 4 post tx, VL120,000) scnds eg. adenomas.
pre sof/led VL 240,000 Fibsc F0
Day 25 <30
Day 32 UND
Week 10 UND
EOT UND ALT11AST17GGT19
SVR4 UND ALT10 AST16 GGT13
SVR8 UND ALT <9 AST16 GGT15
SVR12 UND ALT14 AST19 GGT12 Bili 5
EOT +18 ALT13 AST20 GGT9 Bili 5
EOT +21 ALT11AST15
Cured SVR12
Dysplasia Adenomas RemvdAug '16
SVR24 UND ALT11AST16
ColonoscopyClear Nov17
LumpectomyClear ‘18
LithotripsyCytoscopyBiopsy 4/18
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6 years 3 months ago #14333

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forums.delphiforums.com/generichcvtx

G 1a F-1
Started tx 10/23/15 (Meso sof & led) ALT 48 AST 28 v/l 1.6 mil
11/17/15 4 wk lab ALT 17 AST 16 <15
11/18/15 Started Harvoni
12/16/15 8 wk lab ALT: 15 AST: 13 V/l UND
1/14/16 Fin. Tx
7/07/16 UND SVR 24
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6 years 3 months ago #14349

Wow- The amount of work that must be involved -in all this - Pretty awesome ! :+1:


GT1a Dec14 F2/8.7 VL 900000-2.5M
Jan16 Hepcivir-L MonkMed/Redemption
Baseline: VL 913575 Alt 76 Platelets low
Wk2 VL1157 Alt 23
DET Wk 8 VL 32 Alt19 'In the slow lane'
June16 Fibro 5.7 F0/1 LIF 1.5
Wk 11 VL<12 Alt 13 Det/Unq
Extending tx 12 wks Mylan Sofo/Dac MonkMed
Wk 14 VL <12 Det/Unq
Wk 16 VL UNDETECTED
Wk 22 + 4 Wks Sunprevir FixHepC
Wk 24 UNDETECTED Alt 13
Wk 12 post tx SVR12 Wk 26 SVR24
Thank-you Tim, Dr Debasis @ MonkMed & Dr Freeman @ Fix HepC
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6 years 3 months ago #14356

I agree LG

The presentation is going to be EPIC! Im hoping there will be some well versed "Flipping of the Bird" dished out to all those doubters. :evil:


SVR 24
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6 years 3 months ago #14357

I was happy and honoured to be asked by Hieu to send my path for James, Thank you James for representing us all. Safe travels and keep breaking ground and bread with the usual suspects on our behalf, I appreciate it so much.
Ariel the thankful mermaid.
Mike ty for the link for the flipbook, I have read a fair bit since I woke at 4.30 am haha. Over a week since EOT...sleep patterns slowly resuming. Slowly.....


Gen 1a
Peg/inf/riba 2012(!) stop @ Wk 43 potassium low +issues (rlps week 4 post tx, VL120,000) scnds eg. adenomas.
pre sof/led VL 240,000 Fibsc F0
Day 25 <30
Day 32 UND
Week 10 UND
EOT UND ALT11AST17GGT19
SVR4 UND ALT10 AST16 GGT13
SVR8 UND ALT <9 AST16 GGT15
SVR12 UND ALT14 AST19 GGT12 Bili 5
EOT +18 ALT13 AST20 GGT9 Bili 5
EOT +21 ALT11AST15
Cured SVR12
Dysplasia Adenomas RemvdAug '16
SVR24 UND ALT11AST16
ColonoscopyClear Nov17
LumpectomyClear ‘18
LithotripsyCytoscopyBiopsy 4/18
Last Edit: 6 years 3 months ago by Ariel.
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6 years 3 months ago #14422

The EASL excitement is building..... :woohoo: will be Sunday NZ time I calculate. There is a torrent of UND's and SVR's coming in. I noticed in the flip book Mike posted that a Prof Gane paper is first up on the page of late breakers on the 16th. I think relates to tx naive G3's.

There will be so much useful info coming out of this conference. But I love that Dr Freeman is presenting results that includes everyone, F0-4, all genotypes- this is really what we, and medical profession, need to know now.


Genotype 3 30 years, 2x treatment interferon/ribavirin non responder. Cirrhosis 17 years. Fibroscan, decompensating, 40 down to 22 by 29/3/16- now down to 6.5, normal, no cirrhosis. Started Buyers Club Sof/Dac 14 Nov 15. SVR 12 29/0716
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6 years 3 months ago #14426

I started uploading bloods on my GP2U records for Dr James sometime ago - intending to later add later SVR results - if I am fortunate enough for them to eventuate. However I realised that the results being sought and confirmed by Dr James are for purposes of establishing a multi variate profile of final outcomes with the "generics". Throughout my treatment, and perhaps others, I have used inconsistent regimes of generics from India and Mesochem, but also Daclatasvir provided compassionate grounds and Sofosbuvir from Gilead. It would be impossible I imagine to extrapolate differences or correlations attributable to any particular medication along with other variables (ie genotype, prior tx, cirrhosis etc) - so I realised my data will not add value so I have ceased recording. However, It seems that the numbers of members coming through fully generic treatments is steadily increasing and the data will be interesting for everyone - in its ramifications, both medically but also politically


Fem. Gen 1a.18.4 kPa. IL28b - CT. Cirrhosis 4B/c. MELD 11. Portal Hypertension. Ascites. Varices. (Gr.3). post surgical Coma 2011- Tx denied. 15/09 - INR 1.2 platelets 58 (150-450) albumin 32 (35-50) bilirubin 40 (2-20) ALT 183 (0-45) AST 281(0-41) GGT 39(0-45). Liver lesions AFP 16 <8.
Last Edit: 6 years 3 months ago by Archer. Reason: correct
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6 years 3 months ago #14434

The name is Freeman.
James Freeman.


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forums.delphiforums.com/generichcvtx

G 1a F-1
Started tx 10/23/15 (Meso sof & led) ALT 48 AST 28 v/l 1.6 mil
11/17/15 4 wk lab ALT 17 AST 16 <15
11/18/15 Started Harvoni
12/16/15 8 wk lab ALT: 15 AST: 13 V/l UND
1/14/16 Fin. Tx
7/07/16 UND SVR 24
Last Edit: 6 years 3 months ago by mgalbrai.
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6 years 3 months ago #14437

I'll bet you anything that a video is gonna be made of this generic rebels presentation for all of us to see, that's my hope anyways.




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G1a dx'd in 1992, Biopsy F2 VL 8mill +. Tried tx with Interferon/Riba, back in 2008 didn't last long it felt horribly ugly!! I stopped tx, after 5 weeks!!
Started tx 6/1/16 with Harvoni.
12 Month Labs= UND
Last Edit: 6 years 3 months ago by fretboard.
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6 years 3 months ago #14441

Good luck with the presentation James yours will be the jewell in the crown . Cant wait to see the footsge. Anyone know final cohort numbers? Em


Geno 1b F2/3 snce early 80s. Treated in 2008_9 for 63 weeks on INF/Riba. Commence Sof/Dac on 6 October 2015 and completed 18 weeks of tx. UND at 4-6 weeks, UND at EOT, SVR 2, SVR 6 and SVR 12 on 6 May 2016.
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6 years 3 months ago #14535

I hope the Generic Rebels presentation goes well!! I know it will, how could it go wrong with the likes of our favorite Doctor and all the Rebels in Redemption!? Maybe the next stop will be at the Liver Meeting in the US in November. Wouldn't that be something, Gilead would poo poo their pants.








www.aasld.org/events-professional-develo...r-meeting%C2%AE-2016

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G1a dx'd in 1992, Biopsy F2 VL 8mill +. Tried tx with Interferon/Riba, back in 2008 didn't last long it felt horribly ugly!! I stopped tx, after 5 weeks!!
Started tx 6/1/16 with Harvoni.
12 Month Labs= UND

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6 years 3 months ago #14545

hm, my data is in there somewhere, last bloods good at svr4 now 8, went through all this years ago with my brother on peg/riba, used to pick him up from the clinic with his doses in a cold pack so they wouldnt spoil, allergic to interferon I couldnt take the same route,
now 8 weeks eot I have some of my brain back(I was very ill with hcv mental symptoms) I am back doing IT stuff after a 6 year break working in a factory, just got a new job back in IT, working on panels again, updating systems etc, extra 10k plus car phone etc, long road,, but worth the hike,
cant wait to see docs presentation, Im a difficult patient, but he persisted,
such a big change from how I used to feel,, I smile again, laugh at silly stuff, and no more "Mr Cranky Pants"
So good to become part of the solution after being the problem for so long,
hugs all


TLDR
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