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SVR 24. détected again 7 years 11 months ago #20122
I finished my 3 monts treatment with twinvir 6 months ago and got a non detected result! yesterday I got the result of my new viral 6 months after EOT and it's detected again So what I should do now ? Thank you | |
SVR 24. détected again 7 years 11 months ago #20124
We'll have to re-treat. There are a few of us..... Which genotype are you? This email address is being protected from spambots. You need JavaScript enabled to view it. Genotype 3 VL 4,100,000 ALT 101 AST 71 Treatment Naive Started Sof/Dac Jan 12, 2016 VL= <15 4 weeks in. AST/ALT normal. VL=UNDETECTED 8 weeks in. SVR4= Virus back. 3,300,000 Started generic Epclusa Sep. 23, 2017 4 weeks in <15 *Detected. 12 weeks in <15 *Not Detected. 16 weeks in <15 *Not Detected. Finished 24 weeks treatment 3-17-18 SVR5 <15 Not Detected. SVR 20 <15 Not Detected. SVR 44 <15 Not Detected. Thank you Jesus. Thank you Dr. James | |
SVR 24. détected again 7 years 11 months ago #20129
| Hi JM, So sorry to read this. There should be a few options for you I think, seeing as you just had the Twinvir. Keep the faith LG GT1a Dec14 F2/8.7 VL 900000-2.5M Jan16 Hepcivir-L MonkMed/Redemption Baseline: VL 913575 Alt 76 Platelets low Wk2 VL1157 Alt 23 DET Wk 8 VL 32 Alt19 'In the slow lane' June16 Fibro 5.7 F0/1 LIF 1.5 Wk 11 VL<12 Alt 13 Det/Unq Extending tx 12 wks Mylan Sofo/Dac MonkMed Wk 14 VL <12 Det/Unq Wk 16 VL UNDETECTED Wk 22 + 4 Wks Sunprevir FixHepC Wk 24 UNDETECTED Alt 13 Wk 12 post tx SVR12 Wk 26 SVR24 Thank-you Tim, Dr Debasis @ MonkMed & Dr Freeman @ Fix HepC |
SVR 24. détected again 7 years 11 months ago #20134
JM, Very sorry to hear your news. The newer medications options should be available soon. Good luck, It sounds like you have a good chance of clearing with the next treatment. HCV since 35-40yrs., GT 1a , Dx 2004; VL 4-5 mil, F2-3 Tx sof/led started 3/4/16 4wks VL <15 9 weeks VL UND, ; Alt-15,Ast-13 16 weeks VL UND Alt-20, Ast-22; EOT 24 wks UND SVR 4 UND SVR 12 UND, Alt.15, Ast. 17 SVR 24 UND | |
SVR 24. détected again 7 years 11 months ago #20135
Sorry to hear this. Firstly, I think it is better for you to retest PCR in different good laboratory. In my country (Russia), quality of lab analyses often is not best, and many "false positive" PCR results are registered on internet forums. Probably infected in 1977 2005 - diagnosed with HCV 1b, compensated F4, 15 mln viral load, ALT 320 2005-2006 - PegIFN/rib 48 weeks treatment, relapse 2016 - compensated F4, MELD 8-9, ALT 100-160 2018 - compensated F4, MELD 8, ALT 91 | |
SVR 24. détected again 7 years 11 months ago #20139
Yes | |
SVR 24. détected again 7 years 11 months ago #20151
Hi JM. So sorry to hear your news. I have also relapsed after 24 weeks of treatment. I know it is incredibly disappointing but there are more treatment options now and in the pipeline. We need to take a breath and find out the best way to fight this again. Coral G1a probably early 1980's, Biopsy F1(2010), F2-F3(2015). VL 5+mill; 2+mill (2014) Tx naive. Accessed Sof/Led through Dr Freeman at GP2U and Buyers Club (lifesavers!!!) Commenced tx 12/11/15. 9 wk: VL <15 Detected but LFT = Normal 12 week results: UND (Yay!) Due to slow response commenced Sof/Dac 4 Feb for 12 weeks. EOT @ 24 weeks 27 April 2016. (With thanks to Dr Freeman et al). SVR11 result: VL 1,950,000. It's back! New tx 030916 (Viekira Pak, Solvadi, Ribavirin UND @ 111116. EOT 170217. SVR12 and SVR 24 | |
SVR 24. détected again 7 years 11 months ago #20153
Coral & JM- Sorry about the state of affairs. I imagine generic versions the new meds will be available shortly. They should work for you. m This email address is being protected from spambots. You need JavaScript enabled to view it. forums.delphiforums.com/generichcvtx G 1a F-1 Started tx 10/23/15 (Meso sof & led) ALT 48 AST 28 v/l 1.6 mil 11/17/15 4 wk lab ALT 17 AST 16 <15 11/18/15 Started Harvoni 12/16/15 8 wk lab ALT: 15 AST: 13 V/l UND 1/14/16 Fin. Tx 7/07/16 UND SVR 24 | |
SVR 24. détected again 7 years 11 months ago #20164
Hi JM I am sad to hear this news, I hope you can retreat asap there are many options on the horizon with DAAs as many have said Sending empathy to you at this time Ariel Gen 1a Peg/inf/riba 2012(!) stop @ Wk 43 potassium low +issues (rlps week 4 post tx, VL120,000) scnds eg. adenomas. pre sof/led VL 240,000 Fibsc F0 Day 25 <30 Day 32 UND Week 10 UND EOT UND ALT11AST17GGT19 SVR4 UND ALT10 AST16 GGT13 SVR8 UND ALT <9 AST16 GGT15 SVR12 UND ALT14 AST19 GGT12 Bili 5 EOT +18 ALT13 AST20 GGT9 Bili 5 EOT +21 ALT11AST15 Cured SVR12 Dysplasia Adenomas RemvdAug '16 SVR24 UND ALT11AST16 ColonoscopyClear Nov17 LumpectomyClear ‘18 LithotripsyCytoscopyBiopsy 4/18 | |
SVR 24. détected again 7 years 11 months ago #20189
Hi Jeanmarc, Sorry to hear that you appear to have relapsed as did I recently. As the others say, there are new medications becoming available but my advice would be that your best option is to consider arranging a Skype or telephone consultation with gp2u.com.au . They are up to date on latest treatments and will be able to provide sound advice regarding whether you should retest your viral load as a check and also probably to have a new genotype test to confirm correct treatment going forward. G3a since '78 - Dx '12 - F4 (2xHCC) 24wk Tx - PEG/Riba/Dac 2013 relapsed 24wk Tx - Generic Sof/Dac/Riba 2015/16 relapsed 16wk Tx - 12/01/17 -> 03/05/17 NS3/NS5a + Generic Sof SVR7 - 22/06/17 UND SRV12 - 27/07/17 UND SVR24 - 26/10/17 UND The following user(s) said Thank You: LondonGirl, mgalbrai, Ariel, Fara, Matt-Kenney-google, fitz, Sven, Peach | |
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