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  • 12 May 2016 at 3:55 pm #17041
    dope-on-a-rope.jpgDr James
    • Guardian Angel
    • ★★★★★
    @fixhepc

    Of all the generic Harvoni copies Twinvir has been on the market for the longest so it should come as no surprise that the SVR12 results for it are the first to arrive.

    And what do they say? Well, I just had a look and the news is good.

    First let me mention that making ledipasvir bioavailable is not trivial and that Incepta use the same processes used by Gilead – in other words they have done their homework. I should also mention that like Harvoni, Twinvir is not 100% effective and patients can, will and do fail taking the new DAAs, but….

    Our current results indicate Twinvir delivers the same clinical results as Harvoni so if this is your chosen medication chances are SVR will be yours.

    YMMV

    12 May 2016 at 5:10 pm #17051
    Avatar phototweakmax
    • Guardian Angel
    • ★★★★★
    @tweakmax

    So prof gane is right?

    Important that the ledipasvir is of good quality and twinvir is of good quality

    12 May 2016 at 5:41 pm #17054
    dope-on-a-rope.jpgDr James
    • Guardian Angel
    • ★★★★★
    @fixhepc

    Hi TM,

    Professor Ed Gane was curing people of Hep C before many people on the forum here even knew they had it!

    What he has been trying to say in lay language is that Ledipasvir is a BCS class II medication with high permeability but poor solubility.

    70% of all medications are BCS class II so the science and technology required to make them bioavailable (ie dissolve and get into the body) are well known. Really well known. Pharmacists were doing it before Gilead the company even existed.

    We tested some of the very first Twinvir against Gilead medication from ION-1 and found it equivalent. While it is possible to make a bad generic Incepta do not.

    YMMV

    14 May 2016 at 4:26 am #17154
    Avatar photoGreedfighter
    • Guardian Angel
    • ★★★★★
    @greedfighter

    Look, a Twinvir video that includes info on how to buy it! :cheer: :+1:

    https://youtu.be/N9tX1iGlfkg

    14 May 2016 at 4:39 am #17158
    Avatar photocoral
    • Guardian Angel
    • ★★★★★
    @coral

    Wow! Thanks for posting. What a great little video for promoting low cost medication and the broader message. :+1:

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