Home › Forums › Main Forum › Experts Corner › Fibrosis and Cirrhosis › Emricasan ? Supplier of this API ?

Viewing 4 posts - 1 through 4 (of 4 total)
  • Author
    Posts
  • 8 August 2016 at 10:38 pm #21987
    Oscar
    • Topics: 2
    • Replies: 3
    • Total: 5
    • Novice
    • ★
    @oscar

    Hi people, for those like myself – the latest phase two trial data and follow up data makes this API , worth watching. Has anyone any leads on a supplier of this API

    9 August 2016 at 7:24 am #22000
    dope-on-a-rope.jpgDr James
    • Guardian Angel
    • ★★★★★
    @fixhepc

    Hi Oscar,

    Unless you are near death sick I would adopt a waiting brief on this. Really, even if you are very unwell, and have a MELD > 15 I would treat with DAAs first and see where you are then.

    http://www.worldhepatitisalliance.org/latest-news/infohep/3052483/emricasan-may-improve-inflammation-and-liver-function-people-cirrhosis

    The mechanism of action is caspase inhibition preventing apoptosis which is natural cell death, used for many purposes including killing cancer cells. It would be surprising (to me at least) if this medication did not result in higher HCC rates in cirrhotics.

    YMMV

    19 August 2016 at 9:17 pm #22352
    Oscar
    • Topics: 2
    • Replies: 3
    • Total: 5
    • Novice
    • ★
    @oscar

    Hi James ,I heed what you are saying,but I am 26 weeks SVR GT3A multiple legions and nodes, platlet count 40,on carvedilol. I watch the trial data regarding fibrosis, of all pharma companies through the markets, I have become a cynic of the medical fraternities ethos -? .
    Thankyou for the advice – I am in a wait and observe mode to see how much improvement I get over the next 12 -18 months,but now am a bit more savy after the battle with customs here in WA and then with Mesochem to get the second 3mths of Dacla.
    I am watching several stage 2 trials at the moment.- but I will not mention them as you have refreshed my memory of the desperation felt by all with this virus and will not mention any of the results until I run it past yourself or my specialist . Just getting prepared.
    I hit the medical stonewall last year and was fortunate I had a great GP who gave me the scripts- the major hospital clinics refused.
    I read your paper (EASL) great work !
    I thankyou for your humanity to all James.

    20 August 2016 at 3:56 am #22369
    dope-on-a-rope.jpgDr James
    • Guardian Angel
    • ★★★★★
    @fixhepc

    Hi Oscar,

    Happy to have a private chat about what’s happening out on the bleeding edge to help inform your decisions.

    Best

    J

    YMMV

  • Author
    Posts
Viewing 4 posts - 1 through 4 (of 4 total)
  • You must be logged in to reply to this topic.