Hello HCV2B,

If you were in Australia and I prescribed you Epclusa all I could prescribe would be 12 weeks, regardless of genotype, regardless of cirrhosis.

If you have a look at the EASL guidelines here: https://fixhepc.com/genotype-specific-hepc-treaments.html

You will notice that the only patients where 24 weeks is suggested are GT3 cirrhotic patients.

You have GT2. Knock on wood it’s either the easiest or second easiest (after GT1b) to treat.

12 weeks should be fine.

Anything more than this is probably not required, but some patients elect to take out a little insurance.

Cure rates look something like this:

8 weeks 90%
12 weeks 95% (+5%)
16 weeks 97% (+2%)
20 weeks 98% (+1%)
24 weeks 98.5% (+0.5%)

So what you should notice is that the +5% for the 4 extra weeks after 8 weeks is probably worth it, but that each extra bit of duration delivers less and less extra cure. You might get something like 3.5% extra cure rate for double the duration (and cost).

For a government, this does not make sense. For some patients it does and if the treatment is not causing side effects the only real harm done with overtreatment is to the hip pocket.

With the stupid captcha code can you explain how you login and post and where it appears?

If you just go to https://fixhepc.com/forum and login from there it does not appear for me.