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Fibrosis 6 years 11 months ago #24308
Si after fibroscan of 12 I had ultrasound and gastroscopy. Both were completely normal. I am if course happy but confused at the same time - how could it be that with so high fibrosis ultrasound has not picked up anything at all. Can anyone kindly shed any light on it please? Diagnosed September 2016. 1b ALAT in 40s. VL 460 000 Fibroscan 12.5 Start of treatment 18/10/16 Wk 2 VL 145 Wk 4 VL detected unquantifiable Wk 8 VL detected unquantifiable Wk 12 undetected week 30 after eot - undetected | |
Fibrosis 6 years 11 months ago #24317
Hi countless, U/S looks for abnormalities such as growths and changed blood flow and can also show granularity and other signs of extensive cirrhotic scarring but doesn't tend to pick up fibrosis or inflammation very well. Gastroscopy looks for evidence of portal hypertension. That no issues showed up on either of your examinations is good news. Fibroscan measures the stiffness of the liver and as you were a F3 this would probably have been due to a combination of bridging fibrosis and inflammation. Inflammation tends to resolve with treatment and the evidence from studies seems to show that for many of us the fibrosis will also decrease over time after successful treatment. Perhaps you can get another fibroscan in say 6-12 months to check? G3a since '78 - Dx '12 - F4 (2xHCC) 24wk Tx - PEG/Riba/Dac 2013 relapsed 24wk Tx - Generic Sof/Dac/Riba 2015/16 relapsed 16wk Tx - 12/01/17 -> 03/05/17 NS3/NS5a + Generic Sof SVR7 - 22/06/17 UND SRV12 - 27/07/17 UND SVR24 - 26/10/17 UND | |
Fibrosis 6 years 11 months ago #24322
What Gaj said! Except 12.5 kPa on fibroscan is the border between F3 and F4 so I'd call it F4 (very early). The US is looking for cancer and is poor at picking up fibrosis and mild cirrhosis. Your fibroscan will almost certainly fall to something like 7-9 after treatment because the inflammatory component will go away. You are treating "just in the nick of time". YMMV The following user(s) said Thank You: Donna | |
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