Hi Dr. J,
I did as you suggested and had 2 days on the reduced dose and 2 on the full dose. Day one of reduced I felt much better than I have in ages. Day two however my tummy kicked off again. I have taken the full dose for 2 days and have tummy pains, feeling shivery and don't seem to be able to stay asleep for more than an hour at most.
This does not surprise me though as I have never responded well to medication in the past. It's extremely rare for me to take a painkiller as they upset my stomach so much, and antibiotics make me feel really ill, in fact I have vowed never to take them unless it's a life threatening situation, which is why I rely on herbal medication from my doctor/acupuncturist so much. I was really hoping that this would not be the case with the Sof/dac but it is what it is, and I'll gladly persevere with whatever it throws at me to get rid of my hep c. My feeling is to cut the dose to 45g for a few days to see how I get on - do you agree?
For anyone reading this who hasn't started the treatment yet, please don't be alarmed as I'm really sensitive to chemicals in any shape or form. I can't be in the same room as a plug in air freshener and if I even get the smallest whiff of chlorine from a swimming pool it has a horrible effect on me. So I don't think that I'm the norm in this respect, in fact if there was a graph I would be on the most sensitive side as opposed to the least, and these meds don't affect everyone in the same way as we are all different.
2b diagnosed about 10 years ago
Alt was 150 but got it down to a consistent 49 with Chinese herbal medicine
Started dac/sof 27/03/17
4 week test - liver function normal - alt 31
full blood count normal
RNA detected 26 IU/ml Log = 1.42
9 week test 26/05/17
bloods and liver function normal - alt 27
RNA detected <10 IU/ml