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Daklinza/Sovaldi- side-effects and treatment duration
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Daklinza/Sovaldi- side-effects and treatment duration 6 years 4 months ago #23547

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That is not common and does need checking out. Liver panel and viral load to rule out a relapse and other tests if that's not it.
YMMV

Daklinza/Sovaldi- side-effects and treatment duration 6 years 1 month ago #24299

So am I reading this right youre g-3 f-04 and were treated 2x then december 2017 treated a 3rd time and youre svr? If so I'm curious what the trial you were involved in? was G/P? glecaprivir/pibrentasvir?

Daklinza/Sovaldi- side-effects and treatment duration 6 years 1 month ago #24303

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Hi. It's time to update my situation for reference to future readers. I treated for 16 weeks with Daklinza/Sovaldi. I elected to wait until the 3 month post treatment mark for testing, as my then-side effects began subsiding somewhat. Results came back a week ago and I received good news- I am non-detectable for HCV 3. I will get a final test done next year to give full peace of mind, although I am aware current standing is to take the 3 mth post test as virtually final. My remaining treatment side effects include some neuropathy to hands/feet, some tiredness/mild fatigue and at times a flat mood. I was Genotype 3a with F1, treatment experienced (Pegasus/Ribavirin). Best of luck to all. X
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Daklinza/Sovaldi- side-effects and treatment duration 6 years 1 month ago #24304

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Congratulations on being SVR12, that's great news. Waiting until next year for your final test may be going a bit far. SVR24 is the big one that most of us on this forum are trying to reach.That 24 week post-treatment result should provide you with the certainty you are seeking. In the meantime I hope you can get some good advice about how to deal with your lingering issues. Best wishes!
G2, infected maybe in 1971?
Diagnosed HVnon-A non-B 1980s, revised to HVC 1990's.
Treatment naive. Fibroscan & bloods all normal ranges.
Viral load 7million,
began Redemption trial4, 12-week generic Sof/Vel (Incepta) 2017. Week 4 UND, Week 12UND, SVR24
Thank-yous to my doctor for the script, to Jan at FixHepC for wrangling, and to Dr Freeman for courage.
Kia kaha e hoa ma!

Daklinza/Sovaldi- side-effects and treatment duration 6 years 1 month ago #24306

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Hello AK123,

Congrats on the SVR12. Glad you did 16 weeks - it's clearly better for GT3s.

With the neuropathy please get checked for diabetes and thyroid function. Some B complex vitamins may well do no good but may help and won't do any harm.
YMMV

Daklinza/Sovaldi- side-effects and treatment duration 6 years 1 month ago #24329

Well, I am only ten days after treatment virus free from tests and I am also feeling progressively worse with chronic fatigue, a flat mood/mild depression, unsatisfying sleep (ie waking exhausted) . as some time has elapsed how are you feeling now?
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Daklinza/Sovaldi- side-effects and treatment duration 6 years 4 weeks ago #24403

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That is awesome!!! That gives me hope. I am genotype 3A and am going to o this trial
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Daklinza/Sovaldi- side-effects and treatment duration 5 years 10 months ago #25085

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SVR24- and straight back into full-time employment after a horrendous decade of HCV/interferon hell and accompanying poverty!
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Daklinza/Sovaldi- side-effects and treatment duration 5 years 10 months ago #25087

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#woohoo!

Congratulations AK123!
G3a since '78 - Dx '12 - F4 (2xHCC)
24wk Tx - PEG/Riba/Dac 2013 relapsed
24wk Tx - Generic Sof/Dac/Riba 2015/16 relapsed
16wk Tx - 12/01/17 -> 03/05/17 NS3/NS5a + Generic Sof
SVR7 - 22/06/17 UND
SRV12 - 27/07/17 UND
SVR24 - 26/10/17 UND
:cheer: :cheer: :cheer:
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Daklinza/Sovaldi- side-effects and treatment duration 5 years 10 months ago #25098

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Such a good news story. Congratulations AK123 :woohoo: :woohoo:
G1a probably early 1980's, Biopsy F1(2010), F2-F3(2015). VL 5+mill; 2+mill (2014) Tx naive. Accessed Sof/Led through Dr Freeman at GP2U and Buyers Club (lifesavers!!!)
Commenced tx 12/11/15. 9 wk: VL <15 Detected but LFT = Normal 12 week results: UND (Yay!) Due to slow response commenced Sof/Dac 4 Feb for 12 weeks. EOT @ 24 weeks 27 April 2016. (With thanks to Dr Freeman et al). SVR11 result: VL 1,950,000. It's back!
New tx 030916 (Viekira Pak, Solvadi, Ribavirin UND @ 111116. EOT 170217.
SVR12 and SVR 24

Daklinza/Sovaldi- side-effects and treatment duration 5 years 9 months ago #25152

Hi Gaj,

been busy being cured and all and just come back on the forum for a look and noticed your signature:

SRV12 - 27/07/17 UND!!!

Could not have come across better news - cheers and well done!


Jeff
GT3a 1990 Failed Inter 1998, comb in 2000. HCC 2012
Started 24/52 Sof/Dac 27th October 2015.
1. Bloods 2 October 2015: AST - 165 (20-40), ALT - 265 (5-40), GGT 189 (5-50)
2, Bloods 20 November 2015: ALT etc normal; VL 19
3. Bloods 8 January 2016: AST - 40, ALT - 59, GGT 48 VL RNA UND
4. EOT 12 April 2016 - blood tests: all is well, CT scan: okay
5. AFP 11 June 2016: 4 ref< 11
6. VL July 2016: DET
7. Oct16 start treat - June17 UND
8. Jun 18, lfts okay, platelets a bit low.
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Daklinza/Sovaldi- side-effects and treatment duration
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