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Declatisvir and Solvadi with or without food 8 years 3 weeks ago #14386
Hi all, and to anyone experienced with taking sol/dec. I was wondering if the solvadi and declatisvir is best taken with food . I am taking compounding chemist meds from Kingswood Pharmacy-generics. It seems the online researched drug companies info says with or without food is fine. But some other forum threads on fix hep c , say to take them on an empty stomach- to get best results/absorption uptake. I have for a 4 days been taking the meds with a medium glass of milky yogurt! -then having dinner /food an hour later. *And no nausea etc side effects so far. I thought to take these pills with something rather than nothing may be a good compromise i.e - to line the stomach -to maybe avoid nausea..but also not take too much food -to aid with better absorption /drug uptake. Thank you all! Juen | |
Declatisvir and Solvadi with or without food 8 years 3 weeks ago #14387
Hi Juen For me,I began taking in the morning but then I changed to nights. I didn't take with food particularly, just with water in the morning, also at night. Dac/sof does did not rely on taking with food on an empty stomach. Dac/sof seems to be absorbed differently to led/sof. I think you do need to be aware of the food contraindications however. These are documented on this site. My dac/sof was Mesochem. I did not ever experience nausea. It works X gt 1a VL 6m F2/3 FibroScan - 9KPa in 2011 and 7KPa in 2015 sof/dac 10 December for 12 weeks pre tx alt 85 ast 51 4 wk alt 34 ast 31 UND <35 8 wk alt 29 ast 32 UND <15 12wk alt 25 ast 25 EOT 3.3.16 SVR24 UND KPa5.3 F0 in normal range I am well .forever grateful to fixhepc The following user(s) said Thank You: Juen | |
Declatisvir and Solvadi with or without food 8 years 3 weeks ago #14388
Hi Juen, I take my Sof/Dac when I first wake in the morning then have my morning walk (45mins) to pick up milk and a paper before breakfast. While I suspect it maximises absorption, for me it means I don't forget to take them as they are first task for the day. I haven't had any issues with nausea with the Sof/dac. (Riba is different and I take those with my food) G3a since '78 - Dx '12 - F4 (2xHCC) 24wk Tx - PEG/Riba/Dac 2013 relapsed 24wk Tx - Generic Sof/Dac/Riba 2015/16 relapsed 16wk Tx - 12/01/17 -> 03/05/17 NS3/NS5a + Generic Sof SVR7 - 22/06/17 UND SRV12 - 27/07/17 UND SVR24 - 26/10/17 UND The following user(s) said Thank You: Juen | |
Declatisvir and Solvadi with or without food 7 years 7 months ago #21610
I've been taking mine after food in the afternoon, the food was the advice of my liver nurse! What is the recommendation? It seems a good idea to have food before taking medications? Hope I've been doing the right thing....day 15 today The following user(s) said Thank You: Gaj | |
Declatisvir and Solvadi with or without food 7 years 7 months ago #21616
I think it depends on the meds. I had mine just before bed. That worked for me, only forgot once and got up super early because I remembered in my sleep Genotype 1a Diagnosed in 2004, had HCV for all my adult life. Until 2016!!!! Harvoni treatment, started 19 March 2016 4 week results Bilirubin 12 down from 14 pre treatment, Gamma 25 down from 52, ALT 19 down from 63, AST 19 down from 47, VL <15 down from a lazy 6 million or so EOT Results Bilirubin 10, GGT 18, ALT 19, AST 21, VL UND 12 Weeks post EOT Bilirubin 11, GGT 16, ALT 22, AST 20, VL UND Cured baby | |
Declatisvir and Solvadi with or without food 7 years 7 months ago #21619
Hi Donna, With or without food is fine for Sofosbuvir and Daclatasvir. As I noted previously taking without food just suited my routine best and I didn't notice any problems taking them on an empty stomach. Others have felt they were better off taking with food. The only caution is in the Daclatasvir instruction sheet around taking it with a large, very high fat meal which may reduce adsorption a bit.
packageinserts.bms.com/pi/pi_daklinza.pdf So as long as you don't make a habit of taking them with a Large Big Mac, thick shake and Sunday meal you will be fine either way. G3a since '78 - Dx '12 - F4 (2xHCC) 24wk Tx - PEG/Riba/Dac 2013 relapsed 24wk Tx - Generic Sof/Dac/Riba 2015/16 relapsed 16wk Tx - 12/01/17 -> 03/05/17 NS3/NS5a + Generic Sof SVR7 - 22/06/17 UND SRV12 - 27/07/17 UND SVR24 - 26/10/17 UND | |
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