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Hep C and Me 8 years 3 months ago #7674
| Hi Stew welcome to the forum another Westy like me. I hope it all goes well for you on treatment and if you have any issues don't hesitate to ask here but for the most part treatment on the orals is relatively smooth sailing. Enjoy the ride. Two time relapser. SVR 4 achieved 12/16 at last SVR 12 achieved 22/02/2017 The Bastard has been defeated GT 3 - about 28 yrs with HCV |
Hep C and Me 8 years 3 months ago #7680
Best wishes for your Tx Stew! 3a F0 TX Naive Started Tx 12/12/2015 Kingswood Sof/Dac Pre Tx - ALT 71 AST 40 V/L 9 million Day 11 - ALT 12 AST 15 4 week - LFTs normal - detected (same sample sent for v/l showed undetected) :/ 6 week - UND 12 week EOT - UND SVR4 SVR12 | |
Hep C and Me 8 years 3 months ago #7682
Hi Stew, Good luck with your tx. Please take Dr James's advise, he knows what he's talking about, he's the expert. If you feel you should talk to him there's a GP2U here on this forum. Make an appointment & you can talk to him on the computer. SKYPE's good. Hope you get things sorted with the meds. All the best, Cindi x J the young dragon slayer is: HepC 1a since birth Male aged 15 VL 2000000 Started Twinvir/ 10-11-15-then Sof/led. NO sides so far ! after one week VL : 37 after 4 wks VL : UND ! EOT 2/2/16 UND.! 4 wks. post tx results....pending.... 7/3/16 VL result : 4 week post tx: SVR ! 12 weeks SVR ! 24 wks SVR yeeaa!! The following user(s) said Thank You: Stew-H | |
Hep C and Me 8 years 3 months ago #7697
I was told I could take Nexium as long as I took it at the same time as I took the generic Harvoni. I was advised not to take Ursodeoxycholic Acid if possible as interaction is unknown, however my bile reflux is at a stage where it comes 1st in order of treatment. I'll probably have bloods done after my 2nd week to see if the generic harvoni is working and if I need to drop the nexium which I maybe able to do as its only good for acid reflux - not so much my main problem - bile reflux. Proton-pump inhibitor doses comparable to omeprazole 20 mg or lower can be administered simultaneously with HARVONI under fasted conditions - Gilead Diagnosed Hep C 2013 Geno Type: 1a Treatment: Naïve Cirrhosis F4 2015 GGT 227 AST 79 ALT 89 Platelets 88 2016 Treatment Generic Harvoni Finished 29 March 2016 GGT 30 AST 19 ALP 67 Platelets 91 Qualitative Test Results April 12 Hepatitis C NAT (NA): Not Detected P.C.R Test for Hep C 4th July: Negative Virus Free This email address is being protected from spambots. You need JavaScript enabled to view it. | |
Hep C and Me 8 years 3 months ago #7840
All the best Stew, wishing you a great result and a smooth treatment I am Day 2 here Gen 1a Peg/inf/riba 2012(!) stop @ Wk 43 potassium low +issues (rlps week 4 post tx, VL120,000) scnds eg. adenomas. pre sof/led VL 240,000 Fibsc F0 Day 25 <30 Day 32 UND Week 10 UND EOT UND ALT11AST17GGT19 SVR4 UND ALT10 AST16 GGT13 SVR8 UND ALT <9 AST16 GGT15 SVR12 UND ALT14 AST19 GGT12 Bili 5 EOT +18 ALT13 AST20 GGT9 Bili 5 EOT +21 ALT11AST15 Cured SVR12 Dysplasia Adenomas RemvdAug '16 SVR24 UND ALT11AST16 ColonoscopyClear Nov17 LumpectomyClear ‘18 LithotripsyCytoscopyBiopsy 4/18 The following user(s) said Thank You: Stew-H | |
Hep C and Me 8 years 3 months ago #7935
| I took nexium all the way through treatment when ever I felt like it I don't recall anyone saying it had to be taken at the same time it had no impact on my outcome. Any research I have seen suggests there is no contradiction between them at least none I am aware of. Sob/Dac from Oct 29 2015 Geno 1b Fiberscan 9.9 Pre treatment Fiberscan 7.4 week 10 VL 1.3 million pre treatment Week 2.5 VL 96 Week 5.5 VL 17 Week 10 VL UD SVR 3 UD SVR 16 UD Cured: All liver functions in normal ranges. |
Hep C and Me 8 years 3 months ago #7937
Hi Sir, I think the Dac you're on is okay but Led is a potential issue due to it needing a more acidic stomach environment to be absorbed properly? G3a since '78 - Dx '12 - F4 (2xHCC) 24wk Tx - PEG/Riba/Dac 2013 relapsed 24wk Tx - Generic Sof/Dac/Riba 2015/16 relapsed 16wk Tx - 12/01/17 -> 03/05/17 NS3/NS5a + Generic Sof SVR7 - 22/06/17 UND SRV12 - 27/07/17 UND SVR24 - 26/10/17 UND | |
Hep C and Me 8 years 3 months ago #7947
| You learn something new every day! I'm starting haravoni next week I guess Ill be have to ask about the Nexium when I talk to my Dr, good to know though. Sob/Dac from Oct 29 2015 Geno 1b Fiberscan 9.9 Pre treatment Fiberscan 7.4 week 10 VL 1.3 million pre treatment Week 2.5 VL 96 Week 5.5 VL 17 Week 10 VL UD SVR 3 UD SVR 16 UD Cured: All liver functions in normal ranges. |
Hep C and Me 8 years 3 months ago #7963
Didn't your last treatment work? Diagnosed Hep C 2013 Geno Type: 1a Treatment: Naïve Cirrhosis F4 2015 GGT 227 AST 79 ALT 89 Platelets 88 2016 Treatment Generic Harvoni Finished 29 March 2016 GGT 30 AST 19 ALP 67 Platelets 91 Qualitative Test Results April 12 Hepatitis C NAT (NA): Not Detected P.C.R Test for Hep C 4th July: Negative Virus Free This email address is being protected from spambots. You need JavaScript enabled to view it. | |
Hep C and Me 8 years 3 months ago #7968
I just started Tx yesterday Sof/Dac and have been taking Nexium for a couple of years +. I told the Doc my list of meds when we had our consult and he said everything was fine. I take Nexium as soon as I wake because it's meant to be 1 hr before I eat. I took the Sof/Dac within around 1/2 hr after Nexium yesterday and today. Seems fine so far. Good Luck Stew QLD Australia ☀️ G3a HCV 35 yrs Tx naive Started Sof/Dac 13/01/16 Dec '15 AST 70 ALT 89 GGT 124 Fibroscore 8.5 F1-F2 13 Feb'16 VL UND AST 24 ALT 26 GGT 50H The following user(s) said Thank You: Stew-H | |
Hep C and Me 8 years 3 months ago #8000
I think the problem mainly deals with those who take Ledipasvir - so you should be ok taking nexium. Diagnosed Hep C 2013 Geno Type: 1a Treatment: Naïve Cirrhosis F4 2015 GGT 227 AST 79 ALT 89 Platelets 88 2016 Treatment Generic Harvoni Finished 29 March 2016 GGT 30 AST 19 ALP 67 Platelets 91 Qualitative Test Results April 12 Hepatitis C NAT (NA): Not Detected P.C.R Test for Hep C 4th July: Negative Virus Free This email address is being protected from spambots. You need JavaScript enabled to view it. The following user(s) said Thank You: Jimmy6429 | |
Hep C and Me 8 years 3 months ago #8663
Week 3 has arrived - so far - so good. I stopped taking Nexium after the 1st week as I was diagnosed with bile reflux - not acid reflux so my GP put me on Ursodeoxycholic acid - for the treatment of bile reflux gastritis. It seems to be working except I still wake around 2am with fevers, burning sensations, sweats and heart palpitation. My GP is not sure whether its due to bile reflux, hep C or ulcerative colitis. My GP suggested increasing the Ursodeoxycholic acid to see if it helps any. Off to the liver clinic tomorrow for my first visit since starting treatment. Diagnosed Hep C 2013 Geno Type: 1a Treatment: Naïve Cirrhosis F4 2015 GGT 227 AST 79 ALT 89 Platelets 88 2016 Treatment Generic Harvoni Finished 29 March 2016 GGT 30 AST 19 ALP 67 Platelets 91 Qualitative Test Results April 12 Hepatitis C NAT (NA): Not Detected P.C.R Test for Hep C 4th July: Negative Virus Free This email address is being protected from spambots. You need JavaScript enabled to view it. | |
Hep C and Me 8 years 3 months ago #9313
Three weeks in and I have my LFT's. It seems generic harvoni is working. Before GGT227 Now GGT 88 Before AST 79 Now AST 20 Before ALT 89 Now ALT 12 So there has been a significant improvement in my liver enzymes. This hopefully will prevent further cirrhosis of my liver. Still feel lousy and wake every night with fevers, heart palpitations, sweats and abdo pain, although not as bad as before. I guess these could be contributed to other problems I have caused by cirrhosis of the liver. Diagnosed Hep C 2013 Geno Type: 1a Treatment: Naïve Cirrhosis F4 2015 GGT 227 AST 79 ALT 89 Platelets 88 2016 Treatment Generic Harvoni Finished 29 March 2016 GGT 30 AST 19 ALP 67 Platelets 91 Qualitative Test Results April 12 Hepatitis C NAT (NA): Not Detected P.C.R Test for Hep C 4th July: Negative Virus Free This email address is being protected from spambots. You need JavaScript enabled to view it. The following user(s) said Thank You: Ariel | |
Hep C and Me 8 years 3 months ago #9316
Awesome! This email address is being protected from spambots. You need JavaScript enabled to view it. Genotype 3 VL 4,100,000 ALT 101 AST 71 Treatment Naive Started Sof/Dac Jan 12, 2016 VL= <15 4 weeks in. AST/ALT normal. VL=UNDETECTED 8 weeks in. SVR4= Virus back. 3,300,000 Started generic Epclusa Sep. 23, 2017 4 weeks in <15 *Detected. 12 weeks in <15 *Not Detected. 16 weeks in <15 *Not Detected. Finished 24 weeks treatment 3-17-18 SVR5 <15 Not Detected. SVR 20 <15 Not Detected. SVR 44 <15 Not Detected. Thank you Jesus. Thank you Dr. James The following user(s) said Thank You: Stew-H | |
Hep C and Me 8 years 3 months ago #9318
Hi Stew, Good changes in your LFTs! Less inflammation means less damage being done. G3a since '78 - Dx '12 - F4 (2xHCC) 24wk Tx - PEG/Riba/Dac 2013 relapsed 24wk Tx - Generic Sof/Dac/Riba 2015/16 relapsed 16wk Tx - 12/01/17 -> 03/05/17 NS3/NS5a + Generic Sof SVR7 - 22/06/17 UND SRV12 - 27/07/17 UND SVR24 - 26/10/17 UND The following user(s) said Thank You: Stew-H | |
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