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Beaches Treatment - Harvoni (Aus PBS) 7 years 10 months ago #18486
EOT UND Genotype 1a Diagnosed in 2004, had HCV for all my adult life. Until 2016!!!! Harvoni treatment, started 19 March 2016 4 week results Bilirubin 12 down from 14 pre treatment, Gamma 25 down from 52, ALT 19 down from 63, AST 19 down from 47, VL <15 down from a lazy 6 million or so EOT Results Bilirubin 10, GGT 18, ALT 19, AST 21, VL UND 12 Weeks post EOT Bilirubin 11, GGT 16, ALT 22, AST 20, VL UND Cured baby | |
Beaches Treatment - Harvoni (Aus PBS) 7 years 10 months ago #18487
YAY no more VL!! Blood transfusion in 1992 - Diagnosed in 2007 Tx naive -G1b - F1 VL 2.270.000 ALT 40 Start tx June 4th/2016 with DAAs - Sof/Led from India Bloods on two weeks of tx (June 18th) AST 17 - ALT 10 - GGT 19 Virus UND Bloods on six weeks of tx (July 16th) AST 17 - ALT 8 - GGT 12 Virus UND EOT on August 8th (did 9 weeks and 3 days) SVR 4 Virus UND (September 7th) AST 13 - ALT 5 SVR 14 Virus UND (November 12th) | |
Beaches Treatment - Harvoni (Aus PBS) 7 years 10 months ago #18489
G3a since '78 - Dx '12 - F4 (2xHCC) 24wk Tx - PEG/Riba/Dac 2013 relapsed 24wk Tx - Generic Sof/Dac/Riba 2015/16 relapsed 16wk Tx - 12/01/17 -> 03/05/17 NS3/NS5a + Generic Sof SVR7 - 22/06/17 UND SRV12 - 27/07/17 UND SVR24 - 26/10/17 UND | |
Beaches Treatment - Harvoni (Aus PBS) 7 years 10 months ago #18490
WooHoo, Beaches! Fantastic news!!!! Failed Interferon 96', G1a, VL = 9 - 5.5 Million, F3/A3, AST 111, ALT 190, Generic DAA treatment Sof/Led (Mylan - India MYHEP LVIR) - 8 June, 2016 2 Week Results 20 June, 2016 AST 19, ALT 32 4 Week Results 06 July, 2016 AST 22, ALT 30, VL = 35 6 Week Results 20, July 2016 VL only = HCV RNA Detected, Non-Quantifiable <15 8 Week Results 04 August 2016, Labs, LFTs Normal, VL = UND 12 Week Results 31 August, 2016 LFTs Normal, VL = UND EOT + 4 Weeks, LFTs Normal, VL = UND, "SVR4" SVR12, 21 Nov 2016. CURED!!! | |
Beaches Treatment - Harvoni (Aus PBS) 7 years 10 months ago #18491
| GT1a; Got it some time in the 70's; Diagnosed @1976 Tx naive METAVIR: A2-F2 SOT May 18, 2016: CMP: AST 162 ALT 241 VL 13000000 3 weeks after SOT: AST 27 ALT 31 VL 138 Reached EOT Aug. 10, 2016 / Received svr4 results Sept. 20, 2016: AST 22 ALT 24 Hep C RNA "NOT DETECTED" AS OF 3/20/2017 ,Hep C RNA PCR "NOT DETECTED" THAT'S SVR24! |
Beaches Treatment - Harvoni (Aus PBS) 7 years 10 months ago #18492
Genotype 1a Diagnosed in 2004, had HCV for all my adult life. Until 2016!!!! Harvoni treatment, started 19 March 2016 4 week results Bilirubin 12 down from 14 pre treatment, Gamma 25 down from 52, ALT 19 down from 63, AST 19 down from 47, VL <15 down from a lazy 6 million or so EOT Results Bilirubin 10, GGT 18, ALT 19, AST 21, VL UND 12 Weeks post EOT Bilirubin 11, GGT 16, ALT 22, AST 20, VL UND Cured baby | |
Beaches Treatment - Harvoni (Aus PBS) 7 years 10 months ago #18495
A picture of a thousand words tells a thousand words. Excellent news, beaches! M 61yo HCV+ ~ 30 yrs Gt1a F2 VL 223,000 ALT 54 AST 42 Tx start Sof/Dac 17Dec15. SVR4 at 7Apr16 ALT 22 AST 22 SVR12 at 9Jun16 ALT 23 AST 25 Melbourne, Australia | |
Beaches Treatment - Harvoni (Aus PBS) 7 years 10 months ago #18497
| GT1a; Got it some time in the 70's; Diagnosed @1976 Tx naive METAVIR: A2-F2 SOT May 18, 2016: CMP: AST 162 ALT 241 VL 13000000 3 weeks after SOT: AST 27 ALT 31 VL 138 Reached EOT Aug. 10, 2016 / Received svr4 results Sept. 20, 2016: AST 22 ALT 24 Hep C RNA "NOT DETECTED" AS OF 3/20/2017 ,Hep C RNA PCR "NOT DETECTED" THAT'S SVR24! |
Beaches Treatment - Harvoni (Aus PBS) 7 years 10 months ago #18503
Gen 1a Peg/inf/riba 2012(!) stop @ Wk 43 potassium low +issues (rlps week 4 post tx, VL120,000) scnds eg. adenomas. pre sof/led VL 240,000 Fibsc F0 Day 25 <30 Day 32 UND Week 10 UND EOT UND ALT11AST17GGT19 SVR4 UND ALT10 AST16 GGT13 SVR8 UND ALT <9 AST16 GGT15 SVR12 UND ALT14 AST19 GGT12 Bili 5 EOT +18 ALT13 AST20 GGT9 Bili 5 EOT +21 ALT11AST15 Cured SVR12 Dysplasia Adenomas RemvdAug '16 SVR24 UND ALT11AST16 ColonoscopyClear Nov17 LumpectomyClear ‘18 LithotripsyCytoscopyBiopsy 4/18 | |
Beaches Treatment - Harvoni (Aus PBS) 7 years 10 months ago #18505
1983: Hospitalised with Acute non-A, non-B Hepatitis after ICU blood transfusion 3mths earlier => HCV GT2 22/02/16: (pre-tmt) ALT 61, VL 2.48 IU/ml Hepascore 0.32 (F1/2), fatigue, brain fog, bloating (Treatment Naïve) 10/04/16: (Start tmt) Sofovir +DaclaHep (SOF + DCV) by Hetero Labs in India 09/05/16: ALT 34, VL: NOT Detected 17/6/16 FBG 5.7; PPBG (@14.22) 6.9 (@ 20.45) 7.1; BP 124/72 | |
Beaches Treatment - Harvoni (Aus PBS) 7 years 10 months ago #18513
gt 1a VL 6m F2/3 FibroScan - 9KPa in 2011 and 7KPa in 2015 sof/dac 10 December for 12 weeks pre tx alt 85 ast 51 4 wk alt 34 ast 31 UND <35 8 wk alt 29 ast 32 UND <15 12wk alt 25 ast 25 EOT 3.3.16 SVR24 UND KPa5.3 F0 in normal range I am well .forever grateful to fixhepc | |
Beaches Treatment - Harvoni (Aus PBS) 7 years 10 months ago #18592
| Great news Beaches. Undetected at EOT . Looks like you've just completed a 12 weeks harvoni treatment . Can you tell me what your fibrosis stage was . I too was infected with the hep c virus in 1970. I've completed my 24 week Sof, Led & Riba 11 weeks 5 days ago. Having my SVR 12 blood test Wednesday. Australian Geno type 1a Fibrosis 3-4 Treatment experienced Peg-Interferon Ribavirin (Relapsed) Started 22/10/15 DAA's 24 weeks Sofosbuvir Ledisbovir & 12 weeks Ribavirin Viral Load at week 4 <15 Detected Viral Load at week 12 Undetected Viral Load at week 24 Undetected Viral Load SVR4 Undetected Viral Load SVR12 Undetected |
Beaches Treatment - Harvoni (Aus PBS) 7 years 10 months ago #18594
Happy for you B! You are cured in Dr. Mike's opinion. The rest is, as Holmes would say, "academic".... I hope your 12 week wait flys by stressfree. Mine did. I knew the crap was gone. We both responded very well to tx and look at those enzymes. Not as good as Ariel's, but fish are different... m This email address is being protected from spambots. You need JavaScript enabled to view it. forums.delphiforums.com/generichcvtx G 1a F-1 Started tx 10/23/15 (Meso sof & led) ALT 48 AST 28 v/l 1.6 mil 11/17/15 4 wk lab ALT 17 AST 16 <15 11/18/15 Started Harvoni 12/16/15 8 wk lab ALT: 15 AST: 13 V/l UND 1/14/16 Fin. Tx 7/07/16 UND SVR 24 | |
Beaches Treatment - Harvoni (Aus PBS) 7 years 10 months ago #18595
Hey Michael Henry My fibrosis reading was consistently F0 which is a good thing because my VL was quite high. Fingers crossed for your SVR12 but surely you have it nailed. Evening, Mike I am a fish as well (ocean swimmer whereas Ariel's preference is surfing) but an older fish and probably got infected before Ariel did. Her stats are stellar! I'm feeling pretty relaxed about SVR12. I have a brief holiday planned a few weeks before doing my SVR12 tests - am going to be a fish in Tonga and hopefully swim with my friends the humpback whales Genotype 1a Diagnosed in 2004, had HCV for all my adult life. Until 2016!!!! Harvoni treatment, started 19 March 2016 4 week results Bilirubin 12 down from 14 pre treatment, Gamma 25 down from 52, ALT 19 down from 63, AST 19 down from 47, VL <15 down from a lazy 6 million or so EOT Results Bilirubin 10, GGT 18, ALT 19, AST 21, VL UND 12 Weeks post EOT Bilirubin 11, GGT 16, ALT 22, AST 20, VL UND Cured baby | |
Beaches Treatment - Harvoni (Aus PBS) 7 years 10 months ago #18598
Failed Interferon 96', G1a, VL = 9 - 5.5 Million, F3/A3, AST 111, ALT 190, Generic DAA treatment Sof/Led (Mylan - India MYHEP LVIR) - 8 June, 2016 2 Week Results 20 June, 2016 AST 19, ALT 32 4 Week Results 06 July, 2016 AST 22, ALT 30, VL = 35 6 Week Results 20, July 2016 VL only = HCV RNA Detected, Non-Quantifiable <15 8 Week Results 04 August 2016, Labs, LFTs Normal, VL = UND 12 Week Results 31 August, 2016 LFTs Normal, VL = UND EOT + 4 Weeks, LFTs Normal, VL = UND, "SVR4" SVR12, 21 Nov 2016. CURED!!! | |
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