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Foods that interact with Sof/Led? 8 years 4 months ago #7056

What I was really wondering is whether Ledipasvir fits into the category CYP3A4 type med at all, or whether its totally different, and thus not having the same contraindications as Daclatasvir.
Harvoni 12 wks
Brisbane, Australia
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Foods that interact with Sof/Led? 8 years 4 months ago #7059

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Tomas_73 wrote: I'll probably take my pill with a double espresso and a bite of dark chocolate, 30 minutes before breakfast.

Hey, my kinda guy! Welcome Tomas.

I took my meds last thing at night and slept better than ever. For about 6 hours solid, and that became all I needed (normally 8 hours). Finished meds yesterday, waiting to see if my sleep patterns change...
NSW Australia. Genotype 1b 30+ years, F0-F1, VL 91,000 Feb 2015 (740,000 in 2010), Tx naive.
Ordered Sof/Dac from Buyers Club 21 Sept, received 14 Oct.
Virus UNDETECTED at 3 weeks AND 12 weeks (EOT) AND SVR4 AND SVR12 AND SVR24. :-)
A thousand thankyous to Dr James and the amazing FixHepC team.
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Foods that interact with Sof/Led? 8 years 4 months ago #7060

The two drugs in the earlier posting are Pepcid and Prilosec. I think the main thrust was you can take it, but in limited amounts. I am totally staying away from anything that reduces the normal acid levels in my stomach. As far as meals, I haven't had any issues. I drink my 4/5 cups of Kenyan coffee with my pill, then eat breakfast. I basically went vegan after my diagnosis and quit drinking alcohol. My v/l went from 4.9 million to 1.6 after 8 months. I imagine alcohol was the reason. Hell on the liver.
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G 1a F-1
Started tx 10/23/15 (Meso sof & led) ALT 48 AST 28 v/l 1.6 mil
11/17/15 4 wk lab ALT 17 AST 16 <15
11/18/15 Started Harvoni
12/16/15 8 wk lab ALT: 15 AST: 13 V/l UND
1/14/16 Fin. Tx
7/07/16 UND SVR 24

Foods that interact with Sof/Led? 8 years 4 months ago #7110

Interesting - Needing less sleep would be a revelation for sure. :)
HCV Genotype 1a, Infected circa 1993, Treatment naive.
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