TOPIC:

God they lie!

In the article the Gilead spokesman talks of the non-existance of a pan-genotypic combo, and pumps up their application for approval of their Sofosbuvir/Velpatasvir combo which he says is especially needed for genotype 3 .... totally ignoring that Sof/Dac is approved in the US for Geno3 and approved in the EU as pan-genotypic. And also ignoring that there are two manufacturers of this combo as a single pill in Bangladesh.

While Abbvie, Merck, Johnson&Johnson and Achillion are all mentioned in the article, Bristol-Myers Squibb and their Daklinza (Daclatasvir) is never mentioned a single time.

www.bidnessetc.com/58694-gilead-sciences...ep-closer-to-market/

Sof and Dac the best I think but marketing and greed will see Dac leaft out of the licensed picture at some point.

Hi

I read today that Daclatsavir is not FDA approved. Is that just as treatment for Geno 1?


Thanks

I read today that Daclatsavir is not FDA approved.

Here is the FDA approval announcement for Daklinza (Daclatasvir)

www.fda.gov/NewsEvents/Newsroom/PressAnn...ements/ucm455888.htm

So I guess what you read today was either Gilead marketing material or out of date.

Thanks. I dug a little further. It is definitely approved as treatment for Genotype 3 and, in certain circumstances for Genotype 1. news.bms.com/press-release/us-fda-grants...za-daclatasvir-sndas The way I read this, the US FDA has not yet approved it for wholesale treatment of Genotype 1.

Clearly this is a battle between Gilead and Bristol Myers. Canada and other jurisdictions have approved Dazlinka for treatment of all Genotypes without limitation.

Gotta love the USA.

There is a battle going on between Gilead and everyone else in the world....
M

Yep, and in 2012 Gilead refused to participate in the Phase 3 trials for Sof/Dac with BMS that had progressed through earlier stages under Pharmasett. BMS eventually went it alone.

hepatitiscnewdrugs.blogspot.com.au/2014/...plus-sofosbuvir.html

Who are the criminals anyway. Cheers

I have been wondering for a while why Sof and Dac isn't used more for GT1 and figured it was Gilead pushing BMS out and not wanting to collaborate. Actually my specialist told me in 2011 that there was a drug combo that was near perfect but the companies won't work together. I am guessing he meant Sof and Dac, that was after I failed the Dac Peg and Riba trial.

www.hepatitisc.uw.edu/pdf/treatment-infe...e-1/core-concept/all

www.finance.senate.gov/newsroom/ranking/...4c-ba92-562723ba5255

I saw somewhere that they said 'no more' as soon as they bought Pharmasett but can't find that only the 2012 reference confirming.

Thanks to the Senate for confirming that Gilead is price gouging. They are long on identifying problems, and short on solutions.

The U.S. Congress......
They will probably pass a Senate "resolution", which means exactly nothing. Or they might set up a committee and recommend a bill. It will then go to the floor for debate and then go back to the committee. They will insert the recommendations from the debate into the bill and it will go back to the floor for a vote. If it passes, it will go to the House, where the process starts all over again. After they have made their changes and voted, it will go to conference committee to resolve the differences between the bills. Then both houses have to vote and pass it. Then it goes to the president's desk.......
How many people will die?
Or will they wait until after the presidential election to consider some kind of reform?
The bureaucracy is a ponderous beast.
I don't think we can count on much help from them in the foreseeable future.
We have to do this ourselves. Treatment will continue to be prioritized and people will be waiting for years. Market pressure is our best hope.
Mike

GAJ wrote: Yep, and in 2012 Gilead refused to participate in the Phase 3 trials for Sof/Dac with BMS that had progressed through earlier stages under Pharmasett. BMS eventually went it alone.

hepatitiscnewdrugs.blogspot.com.au/2014/...plus-sofosbuvir.html

Which is how Harvoni came into being for GT1 patients even though it's quite possible Dac may be the superior drug.

More Gilead outrage.

hepatitiscnewdrugs.blogspot.com/2015/12/...gilead-butchers.html

Mike

"Dressed as butchers", lol love it!

And so richly deserved

“let’s hold our price higher regardless of the uproar.”