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Wair - 4 weeks into the treatment 7 years 5 months ago #22560
Hi guys, greetings from Estonia. I have been a silent reader since ... a while. Genotype 3a, diagnosed 2012. Viral load pre tx 7.5 mil, ALT 144 AST 91. Liver biopsy made in 2013, F1 and fatty liver disease. Only treatment available in 2013 in Estonia the traditional interferon/riba treatment. For many reasons (including a breastfed child) I did not start the treatment then and I must say that for couple of years I decided to hide my head in the sand and do nothing. Saddest part was that already in 2013 there were treatments coming that were modern, but again Estonia being an eastern European country - no hope to get those funded here. But now in 2016 I somehow thought that OK, lets face my demons and I was in a way ready in my head to take on the 6m of interferon/riba. Thought that I have not really anything to loose and was prepped to stay at home not to mess with my work life. And then I googled. I landed here and also on Greg Jefferys' blog. Read a lot and then even more. I took the courage to see my doctor to probe what she thinks of new treatments >> there was not much to think, our state still funds the old treatment and she did not want me to think about spending hundreds of thousands on new treatments. I did not do any mention of generics at that point just in case. So - booked an appointment with dr Freeman. Got suggested 3months of Sof/Dac and if needed then another 3m on top of this. Organised the meds to Estonia with Greg Jefferys. I think I have never been so excited to get couple of bottles of meds into my hands My own doctor had postponed my next visit and I also had a longer work trip planned, so started the meds without informing my doctor. The first thing I did after the work trip (2.5 weeks into treatment) - made a quick bloodtest to see the liver functions. And yeiiiii - all down (not in the limit, but still a looooot down). Next day I visited my doctor and then I just said that I did not want to wait and I have at least some proof that I did not make a wrong decision. She seems to be really excited ab this as well. So today - 4w into the treatment. Mental state - amazing. I am just happy all the time. Stress relief? - maybe. But I do have the energy levels up again. I did start exercising again after 2 years - 10 walks and runs. Feeling slightly insomniac. I do wake up at weird times, but again - I am a mother of 2 small girls, I wake up even on slightest noise from their beds. But I still feel a lot better than some months ago. Also had full bloodwork done today. AST 46 ALT 57 Viral load - results not in yet, hopefully by friday. All other stuff (Hgb etc etc) - all in normal ranges as also was in September. OK AST and ALT are not yet in range, but the difference with original is huge. So I dont worry yet too much. I have mentally prepared myself that I need the treatment for 6m anyway, so there is time I think the hardest part now is trying to keep my excitement to myself. For many reasons there are very very few people who know about my disease at all, so therefore the treatment has to be similar secret, at least for now. So thank you to all the people in this forum - even if you are not aware, then there are those silent "lurkers" here who take courage when reading about your paths! Without you I would not be where I am now The following user(s) said Thank You: DrJames, LondonGirl, coral, Gaj, Hieupham, Fara, rohcvfighter, Murr, Mnem | |
Wair - 4 weeks into the treatment 7 years 5 months ago #22561
| Hi Wair, firstly, welcome to the forum And congratulations for having taken the very good decision to get treated. As you already experienced, the side effects are minimal, so do not worry about the slight insomnia. (if allowed a small joke: you have more time to read a good book, see a nice movie You will see that 12 weeks will pass very fast (and if it will be the case for another 12, it will pass also fast).
Here you will find the proper place to share as much happiness you wish Have a nice journey till the finish line (SVR12) ! Cheers, RHF In fiecare an HCV ucide peste 500000 oameni.Medicamentele generice pentru hepatita C functioneaza. Nu deveni statistica! Cauta pe Google “medicamente generice pentru hepatita C”. HCV kills more than 500000 people every year. HCV generic drugs work. Don't become a statistic. By sharing this Youtube video you might save someone’s life! My TX: HEPCVIR-L[generic Harvoni]-India SVR52 achieved The following user(s) said Thank You: wair |
Wair - 4 weeks into the treatment 7 years 5 months ago #22563
| Dear Wair, You have made a very good decision and so lovely to read about you feeling better both mentally and physically You had a large VL to kill and when inflammation is reduced we realise what we have been living with for such a long time ! Delighted for you. Be sure to test at around 8 weeks, just in case you need to extend a little (I did and am now clear of the virus, SVR 12), you may not need to, but it's always good to have plan A, B and C, which is the great thing about this 'alternative' route, which in my opinion is superior. I wish you the best of luck and good health from UK. LG GT1a Dec14 F2/8.7 VL 900000-2.5M Jan16 Hepcivir-L MonkMed/Redemption Baseline: VL 913575 Alt 76 Platelets low Wk2 VL1157 Alt 23 DET Wk 8 VL 32 Alt19 'In the slow lane' June16 Fibro 5.7 F0/1 LIF 1.5 Wk 11 VL<12 Alt 13 Det/Unq Extending tx 12 wks Mylan Sofo/Dac MonkMed Wk 14 VL <12 Det/Unq Wk 16 VL UNDETECTED Wk 22 + 4 Wks Sunprevir FixHepC Wk 24 UNDETECTED Alt 13 Wk 12 post tx SVR12 Wk 26 SVR24 Thank-you Tim, Dr Debasis @ MonkMed & Dr Freeman @ Fix HepC The following user(s) said Thank You: wair |
Wair - 4 weeks into the treatment 7 years 5 months ago #22566
Welcome Wair, Congratulations on making the decision to treat and I'm glad that you've found that like many of us your side effects are minimal. Your LFTs look good and they will improve further as your treatment progresses. I'm sure Dr Freeman will have discussed the indicators for extending treatment with you, including that once your viral load becomes undetected there is little value in continuing to test that during treatment. It is good to hear that you now appear to have the support of your own doctor should you need more testing. Please feel free to share your excitement here like many of us do and best wishes for successful SVR. G3a since '78 - Dx '12 - F4 (2xHCC) 24wk Tx - PEG/Riba/Dac 2013 relapsed 24wk Tx - Generic Sof/Dac/Riba 2015/16 relapsed 16wk Tx - 12/01/17 -> 03/05/17 NS3/NS5a + Generic Sof SVR7 - 22/06/17 UND SRV12 - 27/07/17 UND SVR24 - 26/10/17 UND | |
Wair - 4 weeks into the treatment 7 years 5 months ago #22573
Hello Wair in Estonia (what an international community we are). I also kept my head in the sand for quite some time but I'm so grateful that we decided to poke our heads up and have a look around. My treatment also started with an appointment with Dr Freeman and yes I do understand the excitement of getting those little bottles of tablets. It is such a personal thing in terms of who we tell and if we tell about our Hep C. I think we should continue to control that in the same way that we've taken control of our treatment. So great to hear that your energy has returned - you need it with two young girls. Whether it takes 12 weeks or a little longer you have a HepC free life to look forward to. Be good to yourself. Coral G1a probably early 1980's, Biopsy F1(2010), F2-F3(2015). VL 5+mill; 2+mill (2014) Tx naive. Accessed Sof/Led through Dr Freeman at GP2U and Buyers Club (lifesavers!!!) Commenced tx 12/11/15. 9 wk: VL <15 Detected but LFT = Normal 12 week results: UND (Yay!) Due to slow response commenced Sof/Dac 4 Feb for 12 weeks. EOT @ 24 weeks 27 April 2016. (With thanks to Dr Freeman et al). SVR11 result: VL 1,950,000. It's back! New tx 030916 (Viekira Pak, Solvadi, Ribavirin UND @ 111116. EOT 170217. SVR12 and SVR 24 | |
Wair - 4 weeks into the treatment 7 years 5 months ago #22583
Hey lurker Thank you for posting and adding to information and positivity Well done in becoming proactive Happy for you feeling good From a fellow eastern european Diagnosed September 2016. 1b ALAT in 40s. VL 460 000 Fibroscan 12.5 Start of treatment 18/10/16 Wk 2 VL 145 Wk 4 VL detected unquantifiable Wk 8 VL detected unquantifiable Wk 12 undetected week 30 after eot - undetected | |
Wair - 4 weeks into the treatment 7 years 5 months ago #22633
Negative!!!!!! My viral load is negative for the 4 weeks testing results Jumping up and down (my colleagues think I won lottery, but this is even better than lottery) | |
Wair - 4 weeks into the treatment 7 years 5 months ago #22640
| Fantastic news Wair Looking really good for you LG GT1a Dec14 F2/8.7 VL 900000-2.5M Jan16 Hepcivir-L MonkMed/Redemption Baseline: VL 913575 Alt 76 Platelets low Wk2 VL1157 Alt 23 DET Wk 8 VL 32 Alt19 'In the slow lane' June16 Fibro 5.7 F0/1 LIF 1.5 Wk 11 VL<12 Alt 13 Det/Unq Extending tx 12 wks Mylan Sofo/Dac MonkMed Wk 14 VL <12 Det/Unq Wk 16 VL UNDETECTED Wk 22 + 4 Wks Sunprevir FixHepC Wk 24 UNDETECTED Alt 13 Wk 12 post tx SVR12 Wk 26 SVR24 Thank-you Tim, Dr Debasis @ MonkMed & Dr Freeman @ Fix HepC The following user(s) said Thank You: DrJames |
Wair - 4 weeks into the treatment 7 years 5 months ago #22642
Very happy for you. Always great hearing everybodys results. Genotype 1A ALT 473 AST 226 Virus Load 3,119,030 Results as of May-2016 5 week viral load/undetected as of 12/02/2016 Liver Biopsy Results from Feb 2013 Portal/Periportal chronic inflammation and mild interface hepatitis (Grade 2) Focal Lobular chronic inflammation (Grade 1) Portal/Periportal fibrosis (stage 1-2 trichrome and reticulin stains utilized) Negative Iron stains. The following user(s) said Thank You: DrJames | |
Wair - 4 weeks into the treatment 7 years 5 months ago #22645
Great news Wair. G3a since '78 - Dx '12 - F4 (2xHCC) 24wk Tx - PEG/Riba/Dac 2013 relapsed 24wk Tx - Generic Sof/Dac/Riba 2015/16 relapsed 16wk Tx - 12/01/17 -> 03/05/17 NS3/NS5a + Generic Sof SVR7 - 22/06/17 UND SRV12 - 27/07/17 UND SVR24 - 26/10/17 UND The following user(s) said Thank You: DrJames | |
Wair - 4 weeks into the treatment 6 years 6 months ago #25307
So I have now the final results - 6+ months after the end of treatment - I am officially clear! Viral load UND and all liver enzymes in perfect order! Thank to dr James and Greg, I have put it all behind me! Good luck to all others as well! | |
Wair - 4 weeks into the treatment 6 years 6 months ago #25308
Awesome. God bless you. This email address is being protected from spambots. You need JavaScript enabled to view it. Genotype 3 VL 4,100,000 ALT 101 AST 71 Treatment Naive Started Sof/Dac Jan 12, 2016 VL= <15 4 weeks in. AST/ALT normal. VL=UNDETECTED 8 weeks in. SVR4= Virus back. 3,300,000 Started generic Epclusa Sep. 23, 2017 4 weeks in <15 *Detected. 12 weeks in <15 *Not Detected. 16 weeks in <15 *Not Detected. Finished 24 weeks treatment 3-17-18 SVR5 <15 Not Detected. SVR 20 <15 Not Detected. SVR 44 <15 Not Detected. Thank you Jesus. Thank you Dr. James The following user(s) said Thank You: DrJames | |
Wair - 4 weeks into the treatment 6 years 6 months ago #25309
Great news Wair. G1a probably early 1980's, Biopsy F1(2010), F2-F3(2015). VL 5+mill; 2+mill (2014) Tx naive. Accessed Sof/Led through Dr Freeman at GP2U and Buyers Club (lifesavers!!!) Commenced tx 12/11/15. 9 wk: VL <15 Detected but LFT = Normal 12 week results: UND (Yay!) Due to slow response commenced Sof/Dac 4 Feb for 12 weeks. EOT @ 24 weeks 27 April 2016. (With thanks to Dr Freeman et al). SVR11 result: VL 1,950,000. It's back! New tx 030916 (Viekira Pak, Solvadi, Ribavirin UND @ 111116. EOT 170217. SVR12 and SVR 24 The following user(s) said Thank You: DrJames | |
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