It seems like a lot of people are getting worried about that remark from Prof Gane about the *possibility* of relapsing with certain generics.
Dr James has verified by NMR that all the generics sourced by the FixHepC Buyers Club and that the generics manufactured by the companies recommended on the FixHepC web Forum are chemically equivalent to the patented molecules:
This means that apart from a few minor (and probably irrelevant) arguments about solubility and kinetics, Dr James has done everything humanly possible to show the generics that we all are taking may be assumed to be bio-equivalent to the patented molecules.
As several other people on this thread have already pointed out (mgalbrai, Price, Sirchinenge, GAJ, ...), you just need to look at our forum signatures to see that the FixHepC generics are working extremely well. This is overwhelming evidence that there is no difference between the FixHepC generics and the patented molecules. The NMR spectra say we are taking the correct molecules. All the results posted so far say we are taking the correct molecules. So do not worry, do not fret! Molecules do not know about nationality or packaging. All the evidence so far says that the molecules made in China, India, and Bangladesh are the same molecules as the molecules made for Gilead in Ireland.
Here are some results posted previously by Dr James from previous trials using molecules made in the USA or Europe:
Probably a lawyer would say that NMR doesn't prove bio-equivalence... The final proof will be the results from the REDEMPTION trials. I am sure that once the results are in they will show comparable or better statistics. Probably better because REDEMPTION will be the biggest trial ever.
Personally, I am already absolutely convinced that the generics I have been on are bio-equivalent. But I am a chemist, not a lawyer. REDEMPTION will provide the ultimate proof.
So for what its worth, my advice about the risk of relapse is this - DON'T WORRY, IT WILL PROBABLY NEVER HAPPEN.
But even if the worst does happen, it will be just bad luck and nothing to do with which little country (joke) you got your treatment from.
(Expert in Catapults and Chemistry)