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Sof+Dac combined tablet RVR 7 years 5 months ago #5140

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Hi Enkel

I'm not an expert but I'd then have a crack at Sof/dac/simp as a triple. Not sure about the resistance thing with DAAs I've heard that it is less of a concern than with previous treatments and PIs. Em
Geno 1b F2/3 snce early 80s. Treated in 2008_9 for 63 weeks on INF/Riba. Commence Sof/Dac on 6 October 2015 and completed 18 weeks of tx. UND at 4-6 weeks, UND at EOT, SVR 2, SVR 6 and SVR 12 on 6 May 2016.

Sof+Dac combined tablet RVR 7 years 5 months ago #5141

I don't think the Sim is available as a generic EM I been asking same thing on FB. Just go harder :)
Two time relapser.

SVR 4 achieved 12/16 at last
SVR 12 achieved 22/02/2017 The Bastard has been defeated :):):)

GT 3 - about 28 yrs with HCV

Sof+Dac combined tablet RVR 7 years 5 months ago #5149

It is definitely available, I'm just not aware of anybody yet determining which is the best place to try to get it, any price info, or independently testing the product.

But if it becomes a vital need someone will get those answers, count on it.

www.alibaba.com/countrysearch/CN/simeprevir.html

Sof+Dac combined tablet RVR 7 years 5 months ago #5155

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Yes, but probably go 24 weeks or add Simeprevir or Riba
YMMV

Sof+Dac combined tablet RVR 7 years 5 months ago #5158

  • Enkel
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24 weeks sof/dac or 12 weeks sof/dac/sim?
Male, Fibro F1. Geno 1b. ALT 67 before treatment Viral load 5 million. My huge viral load replicates in my nervous system as I suffer anxiety.
Started Twinvir 12/12/15.
Two weeks
ALT 17 at 2 weeks
Viral Load UND at 2 weeks
ALT 13.5 at 7 weeks EOT
ALT 10.5 at 15 weeks EOT
ALT 13 at 27 weeks EOT, VL UND, Cured

Sof+Dac combined tablet RVR 7 years 5 months ago #5167

Enkel wrote: 24 weeks sof/dac or 12 weeks sof/dac/sim?


I am pretty sure Dr James means 24 weeks Sof and Dac or add Sim for 12 with Sof Dac.
Two time relapser.

SVR 4 achieved 12/16 at last
SVR 12 achieved 22/02/2017 The Bastard has been defeated :):):)

GT 3 - about 28 yrs with HCV

Sof+Dac combined tablet RVR 7 years 5 months ago #5177

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Out of curiosity why would anyone be thinking they might need to repeat treatment?

Its the second thread I've read about thinking they may fail I think its really negative to be thinking
about failure before you've started.

These treatments have a 98% plus success rate!
Sob/Dac from Oct 29 2015
Geno 1b
Fiberscan 9.9 Pre treatment
Fiberscan 7.4 week 10
VL 1.3 million pre treatment
Week 2.5 VL 96
Week 5.5 VL 17
Week 10 VL UD
SVR 3 UD
SVR 16 UD
Cured:
All liver functions in normal ranges.
The following user(s) said Thank You: Enkel, Gaj, zhuk

Sof+Dac combined tablet RVR 7 years 5 months ago #5181

  • Enkel
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Yes, this a "stupid" question by me :).

I have done the genotype test only one time and was 1b. How reliable are these geno test 100% accurate?
Male, Fibro F1. Geno 1b. ALT 67 before treatment Viral load 5 million. My huge viral load replicates in my nervous system as I suffer anxiety.
Started Twinvir 12/12/15.
Two weeks
ALT 17 at 2 weeks
Viral Load UND at 2 weeks
ALT 13.5 at 7 weeks EOT
ALT 10.5 at 15 weeks EOT
ALT 13 at 27 weeks EOT, VL UND, Cured

Sof+Dac combined tablet RVR 7 years 5 months ago #5186

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Hi Enkel,

Very accurate like a DNA test. You only need one.

G
G3a since '78 - Dx '12 - F4 (2xHCC)
24wk Tx - PEG/Riba/Dac 2013 relapsed
24wk Tx - Generic Sof/Dac/Riba 2015/16 relapsed
16wk Tx - 12/01/17 -> 03/05/17 NS3/NS5a + Generic Sof
SVR7 - 22/06/17 UND
SRV12 - 27/07/17 UND
SVR24 - 26/10/17 UND
:cheer: :cheer: :cheer:

Sof+Dac combined tablet RVR 7 years 5 months ago #5187

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I wasn't suggesting its a stupid question I think its perfectly normal to have some concerns.

I guess, I would take comfort in everyone's results thus far, I have yet to see anyone
with a negative outcome.

I am confident you'll get the same positive results we've all enjoyed to date.

And. Deep breaths.
Sob/Dac from Oct 29 2015
Geno 1b
Fiberscan 9.9 Pre treatment
Fiberscan 7.4 week 10
VL 1.3 million pre treatment
Week 2.5 VL 96
Week 5.5 VL 17
Week 10 VL UD
SVR 3 UD
SVR 16 UD
Cured:
All liver functions in normal ranges.
The following user(s) said Thank You: Enkel
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