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TOPIC: 38 years of HepC to first blood results at 4 weeks

38 years of HepC to first blood results at 4 weeks 4 years 2 months ago #26021

  • Tigerfan
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I had 40+ years of HCV, started Epclusa 2.5.18, and was VL Undetected at 3.7.18.

The drug works!
1970's-Bad behavior as a teenager.
2001- Insurance Company denies coverage due to HCV positive
2002- Another HCV positive reading and referral to liver doctor.
2003-Commence Interferon Combination treatment. VL 205,088 after 3 months. Doctor says stop.
2007-VL 1,045,320.
2017-VL 3,121,174.
2.5.18-Commenced generic Epclusa.
3.7.18- VL Undetected!
3.13.18-US Abdomen Complete scan reflects "Normal echogenicity with no mass detected. No dilated intrahepatic biliary ducts".
8.1.18- VL Undetected!
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38 years of HepC to first blood results at 4 weeks 4 years 2 months ago #26025

  • DrJames
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Hello Tigerfan,

That's great news!

Congratulations...
YMMV
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38 years of HepC to first blood results at 4 weeks 4 years 2 months ago #26032

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Congratulations Tigerfan, truly remarkable that after 40 years you're undetected after 4 weeks of treatment. Keep at it for the remaining 8 weeks, and looking forward to your SVR announcement.
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38 years of HepC to first blood results at 4 weeks 4 years 2 months ago #26046

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That's just great news Tigerfan. It seems such a short treatment time compared to how long so many of us carried the virus.
G1a probably early 1980's, Biopsy F1(2010), F2-F3(2015). VL 5+mill; 2+mill (2014) Tx naive. Accessed Sof/Led through Dr Freeman at GP2U and Buyers Club (lifesavers!!!)
Commenced tx 12/11/15. 9 wk: VL <15 Detected but LFT = Normal 12 week results: UND (Yay!) Due to slow response commenced Sof/Dac 4 Feb for 12 weeks. EOT @ 24 weeks 27 April 2016. (With thanks to Dr Freeman et al). SVR11 result: VL 1,950,000. It's back!
New tx 030916 (Viekira Pak, Solvadi, Ribavirin UND @ 111116. EOT 170217.
SVR12 and SVR 24...
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38 years of HepC to first blood results at 4 weeks 4 years 2 months ago #26077

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Great news! You’ll be SVR by June !
Contracted HCV 1980's
Geno Type 1a
F3 ( doc says once treated I'll be F2 maybe F1)
Meds shipped 6/17/2016 arrived early 7/2016

Viral count - 3,471,080

4 week quantitative bloods: August 17, 2016. I have been diagnosed as <15 (told undetected)

8 week quantitative bloods: September 14th. I have been diagnosed as <15 (told undetected)

11 week PCR RNA Qualitative bloods: September 26th 2016 - Undetected

December 19th 2016: Cured!
Viral count: zero!!!
2018 viral count: still zero!
Cured!
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38 years of HepC to first blood results at 4 weeks 4 years 2 months ago #26080

  • Tigerfan
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Here is what I think, my friends:

1. I benefited from contracting the virus in my teens because it allowed the time to permit my juvenile immune system to get stronger as it grew into an adult immune system.

2. After the non-responsiveness to the 2002 F-2 score and Interferon Treatment, I educated myself and changed my diet to significantly include available trial-proven foods and supplements conducive to protecting the liver- milk thistle, dandelion, beets, avocados, etc. Somewhere out there is a study concluding that Phosphatidylcholine (a lecithin derivative) reverses fibrosis; I have been taking it for 15 years.

#1 is a non-scientific hunch derived from the fact that I am a Keith Richards fan. I'll bet I could get #2 admitted as evidence in a court of law that Phosphatidylcholine does indeed reverse fibrosis.
1970's-Bad behavior as a teenager.
2001- Insurance Company denies coverage due to HCV positive
2002- Another HCV positive reading and referral to liver doctor.
2003-Commence Interferon Combination treatment. VL 205,088 after 3 months. Doctor says stop.
2007-VL 1,045,320.
2017-VL 3,121,174.
2.5.18-Commenced generic Epclusa.
3.7.18- VL Undetected!
3.13.18-US Abdomen Complete scan reflects "Normal echogenicity with no mass detected. No dilated intrahepatic biliary ducts".
8.1.18- VL Undetected!
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38 years of HepC to first blood results at 4 weeks 4 years 2 months ago #26081

  • Songbird
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Congrats on the UND result Tigerfan!

S
Diagnosed: 2001 GT1a , HCV since mid-70's.
Biopsy 2010 F1
Fibroscan and Fibrosure 2018 F2

Treated in trial 2010 with Dac/Peg/ Riba and Relapsed.

Resistance test 2017. Have Ns5a Rav Q30r/H58d enhanced from doing Dac.

Start Tx. Jan 18th/18 w/ Vosevi /Riba 12wks. plus 6 wks.Viekira Pak +Sof/Riba(From Dr Freeman @GP2U)

VL start: 1.6mill.ALT 125 AST 88
Wk. 4 Det @LLOQ <15.
VL Wk.8 UND Alt &Ast 22
Wk. 12 UND
EOT:UND

EOT+12 >>>UND (SVR12)! ALT11 AST13
Nov6/18 SVR 24!
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38 years of HepC to first blood results at 4 weeks 4 years 1 month ago #26137

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Wow! Amazing results!
Genotype 1a
Diagnosed in 2004, had HCV for all my adult life. Until 2016!!!!
Harvoni treatment, started 19 March 2016
4 week results Bilirubin 12 down from 14 pre treatment,
Gamma 25 down from 52, ALT 19 down from 63, AST 19 down from 47,
VL <15 down from a lazy 6 million or so

EOT Results
Bilirubin 10, GGT 18, ALT 19, AST 21, VL UND

12 Weeks post EOT
Bilirubin 11, GGT 16, ALT 22, AST 20, VL UND
Cured baby
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