Tag Archives: sofosbuvir,

Life’s most persistent question – What are you doing for others?

A short excerpt from a recently discovered audio recording of the Rev. Dr. Martin Luther King Jr. speaking at Syracuse University in July of 1965. There are some things so dear, some things so precious, some things so eternally true that they’re worth dying for. And if a man has not discovered something that he […]

Newsflash PBAC

In Australia the PBAC has voted to recommend the inclusion of sofosbuvir in the PBS. This could mean that this vital medication becomes available at affordable prices in Australia, however it’s also possible Cabinet will reject this given that inclusion in the PBS could see the current $10 billion spent by the government on all […]

Sofosbuvir Ledipasvir NMR and Mass Spec

We were quite excited to see the first shipment of Chinese sourced Sofosbuvir and Ledipasvir. A white powder and and off white powder, but what would the NMR show? Here’s the NMR for Sofosbuvir which is right on the money. Ledipasvir: mass [M+H] + 889.4195 ( < 2 ppm error) molecular formula – C49H54F2N8O6 Sofosbuvir: […]

Drug Safety Update: Risks of severe bradycardia and heart block when taken with amiodarone

On the 20th May 2015 the Medicines and Healthcare products Regulatory Agency in the UK issued a Drug Safety Update titled: Sofosbuvir with daclatasvir; sofosbuvir and ledipasvir: risks of severe bradycardia and heart block when taken with amiodarone. You will find a link to it at: https://www.gov.uk/drug-safety-update/sofosbuvir-with-daclatasvir-sofosbuvir-and-ledipasvir-risks-of-severe-bradycardia-and-heart-block-when-taken-with-amiodarone

WHO moves to improve access to lifesaving medicines for hepatitis C

GENEVA – WHO today published the new edition of its Model List of Essential Medicines which includes ground-breaking new treatments for hepatitis C. http://www.who.int/mediacentre/news/releases/2015/new-essential-medicines-list/en/ 

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