Home Forums Main Forum Media & News Antibiotic Apocalypse-this is scary

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  • #4377
    Avatar photo2b
    • Guardian Angel
    • ★★★★★
    @2b

    We’ve all read bits about this phenomenon before, but this article seems to be new info and talks about a new ‘mutation” making cross species resistance ot the last resort antibiotic they have:

    http://www.bbc.com/news/health-34857015


    GT 2b; since 80’s, no prior tx, sofosbuvir and daclatasvir compounded from API’s at Kingswood Pharmacy in Sydney, started tx nov 6,2015, undetected at 4 wks, UND at 8 weeks, UND at 1 week after EOT, UND at 4 weeks after EOT and UND at 8 weeks after EOT. I feel GOOD!! I knew that I WOULD!””

    #4399
    Avatar photoCJ
    • Guardian Angel
    • ★★★★★
    @cj

    Very worrying! :(


    J the young dragon slayer is:
    HepC 1a since birth
    Male aged 15
    VL 2000000
    Started Twinvir/ 10-11-15-then Sof/led.
    NO sides so far !
    after one week VL : 37
    after 4 wks VL : UND !
    EOT 2/2/16 UND.!
    4 wks. post tx results….pending….
    7/3/16 VL result : 4 week post tx: SVR !
    12 weeks SVR !
    24 wks SVR yeeaa!!

    #4400
    dope-on-a-rope.jpgDr James
    • Guardian Angel
    • ★★★★★
    @fixhepc

    http://www.thelancet.com/journals/laninf/article/PIIS1473-3099(15)00424-7/abstract

    We need to change the dynamics of our market economy that incentivises giving precious antibiotics to animals to facilitate high density factory farming. The end result is that stuff you could use to save people in the future is being used to improve profits now.

    You, me, and our children are on track to really regret this short sightedness….


    YMMV

    #4403
    Avatar photozhuk
    • Guardian Angel
    • ★★★★★
    @zhuk

    You’re right their Dr James…the more family farms get foreclosed on (and/or bought out by foreign interests/coal gas seam companies) the fewer healthier grass-fed livestock we will produce in this country, leading to concreted farmlots necessitating widespread use of animal antibiotics.

    My cousin on the land is fortunate to have held onto the family landholding into two generations so far, but its not like he turns any profit (as most rural farms don’t)


    GT1a since 1988, diagnosed 1990
    F0, tx naive
    VL 262,000 ALT 40 AST 26 GGT 13 Fibroscan 04/12/15 – 2.9
    Started Mesochem sof/dac 12 weeks 01/01/2016
    11/02/2016 – 6 weeks UNDETECTED
    AST 26
    ALT 26

    #4407
    avatar876.jpegGaj
    • Guardian Angel
    • ★★★★★
    @gaj

    Hi zhuk,

    Please don’t think I am having a go here, I’m not, but I believe it may be worthwhile to point out a difference between yours and the Doc’s posts. True, it is semantics but I think there is something of a lesson in it.

    The Doc talks about the use of life saving antibiotics to facilitate (helps, assists) high density farming to achieve higher profits. On the other hand you say that modern farming practices neccessitate (need, forces) the use of these life saving antibiotics.

    Very similar sounding statements but I would suggest that the Doc’s statement is the one that “Farmco” would present to their potential investors (twisted in a much more positive style and behind closed doors) while your take is the one that they would present to the media for general consumption by the public. I.e. The subliminal implication is “hey, we only do this because we “have” to, not because we want to”

    And to bring it back to this site, we need to think about how Pharmco justify the high price of drugs to the media. We understand that good, healthy profit facilitates funding of high R&D costs for new drugs. OTOH Gilead argues that high R&D costs necessitate them charging $1,000 per pill for Sovaldi.

    Ummmm…..yeeeees, so how much of the (approx) $999 profit per pill goes back into R&D, etc?????


    G3a since ’78 – Dx ’12 – F4 (2xHCC)
    24wk Tx – PEG/Riba/Dac 2013 relapsed
    24wk Tx – Generic Sof/Dac/Riba 2015/16 relapsed
    16wk Tx – 12/01/17 -> 03/05/17 NS3/NS5a + Generic Sof
    SVR7 – 22/06/17 UND
    SRV12 – 27/07/17 UND
    SVR24 – 26/10/17 UND
    :cheer: :cheer: :cheer:

    #4409
    Avatar photozhuk
    • Guardian Angel
    • ★★★★★
    @zhuk

    No worries at all, GAJ. I wasn’t meaning to deflect anything from what the doc said – just wouldn’t like to see us go down the US-road of human antibiotic resistance due to farmed animals having to be fed antiobiotics where we have relatively little farmlot argriculture at present.


    GT1a since 1988, diagnosed 1990
    F0, tx naive
    VL 262,000 ALT 40 AST 26 GGT 13 Fibroscan 04/12/15 – 2.9
    Started Mesochem sof/dac 12 weeks 01/01/2016
    11/02/2016 – 6 weeks UNDETECTED
    AST 26
    ALT 26

    #4413
    Avatar photo2b
    • Guardian Angel
    • ★★★★★
    @2b

    If I’m not mistaken the new TPP (“free trade”;) agreement will require signatories to let in food from any of the other signatories and not even be allowed to put a label on it to tell you its country of origin…not good, because then we won’t even be able to be enlightened consumers to know that what we buy might be coming from a place that is using bad antibiotic practices or who knows what.


    GT 2b; since 80’s, no prior tx, sofosbuvir and daclatasvir compounded from API’s at Kingswood Pharmacy in Sydney, started tx nov 6,2015, undetected at 4 wks, UND at 8 weeks, UND at 1 week after EOT, UND at 4 weeks after EOT and UND at 8 weeks after EOT. I feel GOOD!! I knew that I WOULD!””

    #4421
    avatar876.jpegGaj
    • Guardian Angel
    • ★★★★★
    @gaj
    zhuk wrote:

    No worries at all, GAJ. I wasn’t meaning to deflect anything from what the doc said – just wouldn’t like to see us go down the US-road of human antibiotic resistance due to farmed animals having to be fed antiobiotics where we have relatively little farmlot argriculture at present.

    This is why I sometimes hate the internet, you can’t see my eyes or hand gestures or hear my tone of voice while I speak. :-(

    I didn’t think you were deflecting from what the doc said, in fact I understood you were agreeing and reinforcing it. But the way you expressed it was interesting in that you used the word “necessitating”.

    I was trying to point out that this use of antibiotics is only necessary because the “farmers” involved choose to overcrowd their livestock beyond the natural immune defences of the animals, they choose to employ insufficient staff to be able spot potential illness and then administer the antibiotics to only the sick animals.

    If asked, these same “farmers” will say it is necessary for the health and welfare of the animals and to ensure affordable, disease free food for their customers. This is dishonest, they have options, what they choose is to maximise their profits at the expense of the potential future health of the human race.

    In the same way, big Pharma claim it is necessary to charge high prices to cover high R&D costs required to introduce new and better drugs. This is also dishonest, again they have options, what they choose is to maximise their shareholders profits to whatever the (local) market will bear without regard to peoples health.

    So we should not use their words, necessity, necessitating, necessary, in these circumstances as they imply inevitability. We should keep reminding them and everyone else that they choose these paths that they take and that their choices have consequences.

    sorry….I’ll get off my soapbox now

    G


    G3a since ’78 – Dx ’12 – F4 (2xHCC)
    24wk Tx – PEG/Riba/Dac 2013 relapsed
    24wk Tx – Generic Sof/Dac/Riba 2015/16 relapsed
    16wk Tx – 12/01/17 -> 03/05/17 NS3/NS5a + Generic Sof
    SVR7 – 22/06/17 UND
    SRV12 – 27/07/17 UND
    SVR24 – 26/10/17 UND
    :cheer: :cheer: :cheer:

    #4427
    Avatar photozhuk
    • Guardian Angel
    • ★★★★★
    @zhuk
    Gaj wrote:

    zhuk wrote:

    No worries at all, GAJ. I wasn’t meaning to deflect anything from what the doc said – just wouldn’t like to see us go down the US-road of human antibiotic resistance due to farmed animals having to be fed antiobiotics where we have relatively little farmlot argriculture at present.

    This is why I sometimes hate the internet, you can’t see my eyes or hand gestures or hear my tone of voice while I speak. :-(

    I didn’t think you were deflecting from what the doc said, in fact I understood you were agreeing and reinforcing it. But the way you expressed it was interesting in that you used the word “necessitating”.

    I was trying to point out that this use of antibiotics is only necessary because the “farmers” involved choose to overcrowd their livestock beyond the natural immune defences of the animals, they choose to employ insufficient staff to be able spot potential illness and then administer the antibiotics to only the sick animals.

    If asked, these same “farmers” will say it is necessary for the health and welfare of the animals and to ensure affordable, disease free food for their customers. This is dishonest, they have options, what they choose is to maximise their profits at the expense of the potential future health of the human race.

    In the same way, big Pharma claim it is necessary to charge high prices to cover high R&D costs required to introduce new and better drugs. This is also dishonest, again they have options, what they choose is to maximise their shareholders profits to whatever the (local) market will bear without regard to peoples health.

    So we should not use their words, necessity, necessitating, necessary, in these circumstances as they imply inevitability. We should keep reminding them and everyone else that they choose these paths that they take and that their choices have consequences.

    sorry….I’ll get off my soapbox now

    G[/quote]

    I absolutely agree with you on this, GAJ

    (and not only on the lack of online nuance, can be very misleading/irritating at times for sure!)

    What you have quoted here is absolutely spot-on…and I was thinking specifically of the US when I used the word “necessitating”. You are right this is exactly what a large percentage of their farmers have chosen to do, ignoring their livestock’s wellbeing in the pursuit of ever-larger profit margins. Helped also by the generous Govt subsidies which enable and encourage them to overcrowd (again, for “maximisation” of resources) with no thought of future impacts on the animals, human consumers of the over-medicated end product, or the environment.

    In the same way, big Pharma claim it is necessary to charge high prices to cover high R&D costs required to introduce new and better drugs. This is also dishonest, again they have options, what they choose is to maximise their shareholders profits to whatever the (local) market will bear without regard to peoples health.

    So we should not use their words, necessity, necessitating, necessary, in these circumstances as they imply inevitability. We should keep reminding them and everyone else that they choose these paths that they take and that their choices have consequences.

    A very valid analogy, and well said GAJ.

    Being of a rather naturally cynical bent, I probably should have used the word “necessity” in parentheses, as that was definitely the tone intended. Sorry for any misunderstanding on that front :)


    GT1a since 1988, diagnosed 1990
    F0, tx naive
    VL 262,000 ALT 40 AST 26 GGT 13 Fibroscan 04/12/15 – 2.9
    Started Mesochem sof/dac 12 weeks 01/01/2016
    11/02/2016 – 6 weeks UNDETECTED
    AST 26
    ALT 26

    #4429
    avatar876.jpegGaj
    • Guardian Angel
    • ★★★★★
    @gaj

    Nah, all good mate. Was just reading your Leunig post in the other thread and suspect we had a similar moment but in this case with best intentions from both sides.

    G


    G3a since ’78 – Dx ’12 – F4 (2xHCC)
    24wk Tx – PEG/Riba/Dac 2013 relapsed
    24wk Tx – Generic Sof/Dac/Riba 2015/16 relapsed
    16wk Tx – 12/01/17 -> 03/05/17 NS3/NS5a + Generic Sof
    SVR7 – 22/06/17 UND
    SRV12 – 27/07/17 UND
    SVR24 – 26/10/17 UND
    :cheer: :cheer: :cheer:

    #4451
    Avatar photozhuk
    • Guardian Angel
    • ★★★★★
    @zhuk

    No probs mate. The internet/social media can be an awkward beast at the best of times heh :)


    GT1a since 1988, diagnosed 1990
    F0, tx naive
    VL 262,000 ALT 40 AST 26 GGT 13 Fibroscan 04/12/15 – 2.9
    Started Mesochem sof/dac 12 weeks 01/01/2016
    11/02/2016 – 6 weeks UNDETECTED
    AST 26
    ALT 26

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