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- This topic has 66 replies, 14 voices, and was last updated 8 years, 3 months ago by Serg.
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9 August 2016 at 1:22 pm #22013
Hi pat1, no problem
Probably infected in 1977
2005 – diagnosed with HCV 1b, compensated F4, 15 mln viral load, ALT 320
2005-2006 – PegIFN/rib 48 weeks treatment, relapse
2016 – compensated F4, MELD 8-9, ALT 100-160
2018 – compensated F4, MELD 8, ALT 919 August 2016 at 2:29 pm #22014Serg wrote:Another question is possible – if we possibly have initial 7% blip of HCC risks after treatment, then, does it mean that treatment with DAAs with cirrhosis looks like some sort of “Russian roulette” game with 1 “HCC-bullet” per 13 empty chambers?
Only if we wish to be over-melodramatic Serg. Most people would call it a risk-benefit analysis and weigh up the two sides and make a decision that is appropriate for them just like they would with any other medical procedure.
G3a since ’78 – Dx ’12 – F4 (2xHCC)
24wk Tx – PEG/Riba/Dac 2013 relapsed
24wk Tx – Generic Sof/Dac/Riba 2015/16 relapsed
16wk Tx – 12/01/17 -> 03/05/17 NS3/NS5a + Generic Sof
SVR7 – 22/06/17 UND
SRV12 – 27/07/17 UND
SVR24 – 26/10/17 UND
9 August 2016 at 3:45 pm #22019Gaj
Sorry if “russian roulette” analogy seems as some “over-melodramatic” “negative connotation” or something like that. I had read mentioned by you Dr.James’s posting with similar analogy and decided that this analogy is ok for this forum.
Probably infected in 1977
2005 – diagnosed with HCV 1b, compensated F4, 15 mln viral load, ALT 320
2005-2006 – PegIFN/rib 48 weeks treatment, relapse
2016 – compensated F4, MELD 8-9, ALT 100-160
2018 – compensated F4, MELD 8, ALT 919 August 2016 at 5:04 pm #22020To be clear, I cited the thread not the analogy that was included in a post within it and I made no statements about “negative connotation” or that the analogy should not be used on the forum. I do stand by what I stated.
G3a since ’78 – Dx ’12 – F4 (2xHCC)
24wk Tx – PEG/Riba/Dac 2013 relapsed
24wk Tx – Generic Sof/Dac/Riba 2015/16 relapsed
16wk Tx – 12/01/17 -> 03/05/17 NS3/NS5a + Generic Sof
SVR7 – 22/06/17 UND
SRV12 – 27/07/17 UND
SVR24 – 26/10/17 UND
9 August 2016 at 6:04 pm #22023Good, no problem. Yes, I agree that usually we need to weigh up two sides.
Probably infected in 1977
2005 – diagnosed with HCV 1b, compensated F4, 15 mln viral load, ALT 320
2005-2006 – PegIFN/rib 48 weeks treatment, relapse
2016 – compensated F4, MELD 8-9, ALT 100-160
2018 – compensated F4, MELD 8, ALT 9110 August 2016 at 3:04 pm #22062I like the pack of straws analogy for probability.
I explain 90% as being like pickingfrom a pack of 10 straws. 1 person gets the short one, 9 don’t.
When I grew up straws were more common than revolvers and Russian Roulette. The scene from the movie “The deer hunter” put me off that game. Great guitar tune though….
[video]https://youtube.com/watch?v=sA_qnNrVelc[/video]
YMMV
10 August 2016 at 6:15 pm #22066Yes, pack of straws is more peaceful analogy… Great movie, great guitar…
Probably infected in 1977
2005 – diagnosed with HCV 1b, compensated F4, 15 mln viral load, ALT 320
2005-2006 – PegIFN/rib 48 weeks treatment, relapse
2016 – compensated F4, MELD 8-9, ALT 100-160
2018 – compensated F4, MELD 8, ALT 91 -
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