Sundance wrote:
I spoke to James Freeman when I was just starting treatment and at the time this was his suggestion as I was reluctant to have the Ribovirin, so I will just take it for the last for weeks I was not detected at 4 weeks into treatment. So I will just try if I can tolerate it for 4 weeks.
One thing you should know about ribavirin is that it has a long half life and takes quite some time to accumulate in your blood. In fact, it takes about four weeks to reach equilibrium levels, so if you take it for that period, it will just be reaching its high point when you stop using it.
What that actually means in terms of treatment, I don’t know, but no-one is very clear about how ribavirin works in any case.
Here is a link to a good paper with the relevant graph on the third page:
Ribavirin paper
G4, F4, cirrhosis.
Thank you to Gilead, Michael Sofia, and the terrific folk at FixHepC for making this adventure possible.
YEAR….. ALT….. AST….. GGT… FERRITIN………………………………….
2009……. 210….. 215….. 953….. 1400……….. (Bad health, stupidity)
2015……. 60……. 45……. 150….. 360…………. (Improved diet and health, FixHepC treatment)
2016……. 20……. 24……. 25……. 156…………. (SVR 12)