- This topic has 5 replies, 4 voices, and was last updated 7 years, 11 months ago by
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Hi Janet,
The short answer is that Sofosbuvir has a half life of about one day (27hrs) so the approximate concentration in your body halves each day once you have finished treatment. Eg.
EOT 100%
Day 1. 50%
Day 2. 25%
Day 3. 12%
Day 4. 6%
Day 5. 3%
Day 6. < 2% Day 7. < 1% Daclatasvir's half life is 12-15hrs so will clear from your body twice as fast so both these meds are mostly gone from our bodies very quickly. Here is a more detailed explanation from Dr Freeman on how long it takes before Sof/Led are completely gone.
G3a since ’78 – Dx ’12 – F4 (2xHCC)
24wk Tx – PEG/Riba/Dac 2013 relapsed
24wk Tx – Generic Sof/Dac/Riba 2015/16 relapsed
16wk Tx – 12/01/17 -> 03/05/17 NS3/NS5a + Generic Sof
SVR7 – 22/06/17 UND
SRV12 – 27/07/17 UND
SVR24 – 26/10/17 UND
Wow, thanks Gaj! I knew someone on here would come up with the answer. I’m so impressed with the entire generic Hep C meds community. There’s always someone, somewhere willing to give their time to answer my questions. I’ve had far more support than the NHS were willing to give me. Funny that, when it was them who infected me in the first place.
Phew, that’s a relief…….
Aaaaah!!! That’s better.
(It appears the recommendation refers to reducing Harvoni side effect of headaches rather than reducing the medication’s effectiveness.)
G3a since ’78 – Dx ’12 – F4 (2xHCC)
24wk Tx – PEG/Riba/Dac 2013 relapsed
24wk Tx – Generic Sof/Dac/Riba 2015/16 relapsed
16wk Tx – 12/01/17 -> 03/05/17 NS3/NS5a + Generic Sof
SVR7 – 22/06/17 UND
SRV12 – 27/07/17 UND
SVR24 – 26/10/17 UND
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