Home Forums Main Forum Genotype Specific Genotype 3 (37%) Sof/dac and autoimmune disease arthritis

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  • #25674
    dope-on-a-rope.jpgDr James
    • Guardian Angel
    • ★★★★★
    @fixhepc

    Hi Jan,

    Sorry to hear about your problem Janet.

    Often we see arthritic stuff, and autoimmune stuff get better.

    What I have seen is the medications cause a flare up of gout, and although this is typically seen in the big toe, and often only on one side, it can affect any joint so I would certainly have your serum urate level checked.

    Certainly a checkup of you autoimmune markers and gout markers would be in order. Prednisolone works for both, and although the preference would be not to use it, we may have to consider it to damp things down. A short course should not adversely impact on treatment success.


    YMMV

    #25676
    Janet UK
    • Topics: 4
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    • Acolyte
    • ★★
    @janet-uk

    Thank you, James. I’ll ask my GP to check those levels.

    I had been considering extending Sof/Dac to a 16 week course instead of 12, just to give myself a better chance of success, but if the arthritic problems are being aggravated by the treatment I’m not sure whether that’s a good idea or not. Perhaps, given that the virus was undetectable in less than 4 weeks, I really don’t need to… It’s a devil and deep blue sea situation.


    Infected 1981 by contaminated blood products
    Geno 3
    Interferon/Ribavirin 2009 relapsed after EOT
    Generic Sof/Dac started 28 Jan 2017
    Baseline VL 24.7 million
    UNDETECTED after 26 days.

    #25677
    dope-on-a-rope.jpgDr James
    • Guardian Angel
    • ★★★★★
    @fixhepc

    Undetected at 4 weeks is a good sign but your VL of 24 million is the highest I’ve ever seen in GT3. 16 weeks is a good idea in GT3 and definitely worth considering.


    YMMV

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