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24 weeks treatment with Harvoni
24 weeks treatment with Sofosbuvir + Daclatasvir
12-24 weeks treatment with Sof/Dac or Sof/Led plus Simeprevir
Abbvie Viekira Pak
So longer, stronger or different.
YMMV
Treatment emergent serious adverse events occurred in 18 percent of patients and nine patients died.
If you remove the placebo patients the n was 1593 so the death rate was 1 in 177.
YMMV
Just a quick bit of advice if I may ask……when I have finished my treatment in 7 weeks do I have another VL test then or do I wait for 3 months after I have finished? I think that wait will be more stressful than the last four weeks of waiting
The PROTON trial of 200 vs 400 of Sofosbbuvir showed that on the 400 mg dose 100% of people who went undetected on treatment stayed UND at EOT (End of treatment) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3968818/table/table1-1756283X13515825/ For the 200 mg dose only 94% hit UND at EOT but the SVR of 90% was almost the same as the 91% for the 400 mg dose.
So in English if you’ve hit UND on treatment you will be UND at EOT so doing a test then is academic. Nice to see, but basically useless.
At 4 weeks post treatment UND means a 96% chance of absolute cure, and at 12 weeks UND means 99%.
YMMV
Hello everyone
The Doctor just gave me my blood test results and has asked me to see if the following may have something to do with the medication.
Neutrophils 1.9
Platelets 148Apparently these are just a little bit lower than normal and nothing to worry about but as I have never had results like this before he just wanted me to check. Will follow up again in one month. Liver function test was perfect!
Thanks in advance.
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I don’t think that EVERYONE will get the treatment…it will be those who are very unwell (as it should be) but will be triaged for sure. I can’t imagine that anyone diagnosed with Hep C, no matter how advanced (or not advanced), would want to put off treatment. I don’t for a moment regret accessing my meds and am well on the way to a cure. If I were to wait for the Hospital system to get treatment I suspect it would be a long wait. I am still on the waiting list for an appointment (which could be 18 months away). I think there will be many more people going down the generics road because $1 billion over five years won’t go that far really.
Maybe I am a bit cynical but I have no trust nor faith in our Government or our politicians, on any level.
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Just saw my story on the “Speak Out” forum with Hep Australia which I posted on 8/12. Glad they approved and posted it……..I made it short and sweet but to the point. It’s great to see that word is “getting out there”. It was the first site I visited when I found out I had the virus.
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Kingswood were using Gelatin caps that had this problem. Now they are using vegie caps that don’t. Problem solvered.
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Well done Folho, good on ya,
LG so glad you are getting closer to treatment. has been a cake walk for me so far. Just so happy to be getting better and giving my body a chance to heal. Day 25 on APIs, Hope you have an easy time of it also.
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Thank you all for your posts…..this Forum has kept me “sane” through the last five weeks and I confess I have a bit of a laugh at some of the posts. Laughter is good for the soul apparently. I am off to see my GP on Monday with a nice bottle of Red to give to him for Xmas. He has been a great support to me and no doubt will be on board with his other Hep C patients now.
Just a quick bit of advice if I may ask……when I have finished my treatment in 7 weeks do I have another VL test then or do I wait for 3 months after I have finished? I think that wait will be more stressful than the last four weeks of waiting
I still have insomnia and a few headaches but nothing I can’t cope with and my energy levels are much better too. I also feel a sense of “calm” which I haven’t had for a very long time.
I wish you all a very Merry Xmas and a happy healthy 2016.
My heartfelt thanks go to Dr Freeman
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http://fixhepc.com/forum/gt3/369-gt3-high-svr-rates-with-daclatasvir.html
If you look at this post and the pdf you can see that for n=468 F3/F4 patients on Sof/Dac +/- Riba that for everyone who did 24 weeks the – Riba groups out performed the + Riba groups.
Based on this being the biggest trial and best evidence to date I would be going…..
Drugs (ribavirin), just say no.
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Hi All,
tasCAHRD have created a new dedicated location for HCV donations:
https://www.givenow.com.au/fixhepc
This will ensure that these donations are directed towards HCV only.
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And quite surprised too that science seems to have managed to come up with something really useful for a change.
But where’s my hoverboard?
[video]https://www.youtube.com/watch?v=eOH15_pqWZ4[/video]
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Yes, but probably go 24 weeks or add Simeprevir or Riba
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Hi Jaz I start my fifth week of treatment this week. Only side effect I have had is insomnia. Was very tired throughout the day for the first week (I take my capsules around 8.00pm) but have now noticed, even though I am waking early, that my energy levels throughout the days have improved greatly. I work full time and have had no problems at work (other than yawning a lot for the first week) Good luck with your treatment. I have found this forum to be wonderful and pretty much any question/doubts you may have can be answered here.
Cheers Lynne
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