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Viewing 15 posts - 1,246 through 1,260 (of 1,968 total)
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  • in reply to: Feels like possible relapse – plan not panic! #16161
    dope-on-a-rope.jpgDr James
    • Guardian Angel
    • ★★★★★
    @fixhepc

    Hi Phoenix,

    Please get LFTs as well. If your ALT is out of range you are probably right, if it is still normal that would be reassuring.

    If we need to retreat you that’s possible and can be prompt.

    Best

    James


    YMMV

    in reply to: Ready to start treatment #16156
    dope-on-a-rope.jpgDr James
    • Guardian Angel
    • ★★★★★
    @fixhepc

    A simple ALT is a good quick check. In all the relapses we’ve seen a significantly elevated ALT has flagged it a week before the viral load has come back.


    YMMV

    in reply to: Honker Heads for Hobart #16145
    dope-on-a-rope.jpgDr James
    • Guardian Angel
    • ★★★★★
    @fixhepc

    Congratulations Honker!!! Enjoy your travels :)


    YMMV

    in reply to: EASL Presentation – Language translators wanted #16117
    dope-on-a-rope.jpgDr James
    • Guardian Angel
    • ★★★★★
    @fixhepc

    Yes, in terms of timelines Chinese generics started for me last March, by Late May there was Indian Sofosbuvir but no NS5A, just RIBA. In August the Bangladesh stuff starts to arrive. So almost all the SVR4/12/24 relate to this, because….

    The first of the Indian generic Harvoni and Daclatasvir appears on 15th December so the SVR4s from that are just starting to arrive given shipping, 12 weeks treatment, 4 weeks and then the 1-2 week test delay.

    We do have the first few Indian SVR4s trickling in.


    YMMV

    in reply to: EASL Presentation – Language translators wanted #16101
    dope-on-a-rope.jpgDr James
    • Guardian Angel
    • ★★★★★
    @fixhepc

    Mandarin would be great.


    YMMV

    in reply to: Where are the hordes of Newbies? #16095
    dope-on-a-rope.jpgDr James
    • Guardian Angel
    • ★★★★★
    @fixhepc

    Yes, this is good but…..

    Most sadly patients don’t know what a generic is. There is a lot of searching going on – about 2.25 million searches a month according to Google but the words ordinary people (as opposed to people on forums like this use) don’t currently bring us up:

    ScreenShot2016-04-24at12.29.21pm.png


    YMMV

    in reply to: Where are the hordes of Newbies? #16086
    dope-on-a-rope.jpgDr James
    • Guardian Angel
    • ★★★★★
    @fixhepc

    Hi GF,

    Yes there was a blip, but that was it.

    ScreenShot2016-04-24at11.30.53am.png

    While the coverage in the medical press was nice virtually no patients read that sort of thing. What would have been nice, but did not happen was for the New York Times, Washington Post, or Boston Globe to pick up the story and push it into the mainstream media. Sadly the story of generics working was considered insufficiently interesting.

    The blips on the traffic chart correspond closely with mainstream media attention, and to get the message out there that’s where it has to appear.

    There has been interest from doctors across the world, but that will only result in a slow organic growth. What would really kick it is having patients opening the discussion of generics with their doctors, but for now most patients don’t know it’s a viable option.


    YMMV

    dope-on-a-rope.jpgDr James
    • Guardian Angel
    • ★★★★★
    @fixhepc

    Yes he contacted me earlier on private chat…said he was from a place in India that made the Hep C drugs and wanted to know if he could help me in any way. I just said I had finished my course of treatment and was just waiting on the final blood test for SVR. He said there were Indian Doctors who could help. Wanted to know where I was from and I told him Australia and then I logged off.


    YMMV

    in reply to: US Moderator announces our drugs are ILLEGAL #16051
    dope-on-a-rope.jpgDr James
    • Guardian Angel
    • ★★★★★
    @fixhepc

    I find myself 72.727273% in agreement with Joy, she just uses too many words…..

    I’d LOVE to see the whole world cured.

    She only missed

    ….. this year

    We have the power to fix hep c. The real question is do we have the will power? The will power to see cure deployed on a mass scale, and deployed now.


    YMMV

    in reply to: REDEMPTION-2 and 3 Timelines #16047
    dope-on-a-rope.jpgDr James
    • Guardian Angel
    • ★★★★★
    @fixhepc

    Hi Matt,

    Yes. There was a recent delay when 50 planes in India had bomb hoaxes and all cargo was offloaded. Clearing the backlog all perishable stuff shipped first but I am told it is getting back to normal.


    YMMV

    in reply to: Nobel Prize? #16013
    dope-on-a-rope.jpgDr James
    • Guardian Angel
    • ★★★★★
    @fixhepc

    Australian of the Year perhaps!


    YMMV

    in reply to: Diplomat on Twinvir #16004
    dope-on-a-rope.jpgDr James
    • Guardian Angel
    • ★★★★★
    @fixhepc

    Alcohol usually causes isolated GGT elevation. It’s not that it can’t cause other enzymes to go up but more commonly it’s the GGT which is out of range. If you look at HCV when you remove the liver damaging insult the ALT is the first to fall (it only hangs round for a short time) – the AST and GGT follow it down, but are slower. The LDH and ALP are slowest.


    YMMV

    in reply to: Diplomat on Twinvir #15999
    dope-on-a-rope.jpgDr James
    • Guardian Angel
    • ★★★★★
    @fixhepc

    Hi Diplomat,

    Your LFTs suggest something else is going on. If it’s not HBV we (as in some doctor or other) needs to work their way down the list of likely suspects. Checking your iron studies would be high on my list of next things to do.

    It’s a big list but please have a look at: http://www.medicinenet.com/liver_blood_tests/page7.htm and the following pages. One (or more) of those is probably at root cause.

    The key point is that your ALT/AST have not normalised so there MUST be something else driving it (now that we know the HCV is no longer the issue).


    YMMV

    in reply to: Quote of the day #15992
    dope-on-a-rope.jpgDr James
    • Guardian Angel
    • ★★★★★
    @fixhepc

    God, grant me the serenity to accept the things I cannot change,
    Courage to change the things I can,
    And wisdom to know the difference

    Reinhold Niebuhr (1892–1971)

    Or, if you like nursery rhymes….

    For every ailment under the sun
    There is a remedy, or there is none;
    If there be one, try to find it;
    If there be none, never mind it.

    W.W. Bartley (1934-1990)


    YMMV

    in reply to: Diplomat on Twinvir #15985
    dope-on-a-rope.jpgDr James
    • Guardian Angel
    • ★★★★★
    @fixhepc

    Hello Diplomat,

    Those LFTs are unusually high for EOT. I would wonder if you have something else going on as well with chronic Hep B being pretty high on the list.

    Have you had HepB surface antigen, HepB core antibody, HepB surface antibody done?

    You should also have an alpha feto protein (AFP)

    If you don’t have Hep B I would be looking for haemochromatosis next – iron studies and if elevated look for the genetic markers.

    Your LFTs should be much better than they are – please don’t ignore this. There is something else to find.


    YMMV

Viewing 15 posts - 1,246 through 1,260 (of 1,968 total)