I gained 4 kg Didn’t need it really but at 60 I’m not going to fret too much about it

Gilead must be pretty pissed about now…..

Gilead are businessmen. Amoral perhaps, but businessmen all the same. They will always have known their high price run was time limited, although generic competition may not have factored into their timelines.

Gilead’s decision is simple – if they chase us they give the generic flame oxygen. Media oxygen.

Ignoring generics is their best option and what they have been doing. If you look at the upside/downside risk, selecting do nothing is the way to go.

I doubt a bit of anger is going to make them drop the ball. They may be bastards, but they aren’t stupid.

It is in the quotes section but this one from JFK bears repeating:

“The great enemy of truth is very often not the lie–deliberate, contrived and dishonest–but the myth–persistent, persuasive and unrealistic. Too often we hold fast to the cliches of our forebears. We subject all facts to a prefabricated set of interpretations. We enjoy the comfort of opinion without the discomfort of thought”

– JKF Commencement Address at Yale University, June 11 1962

Gilead are charging outrageous prices for an inexpensive medication they did not invent. They do not even pay their taxes. Citizen payers are dying due to their pure unadulterated greed.

http://www.bloomberg.com/news/articles/2015-02-26/gilead-avoids-billions-in-u-s-taxes-on-its-1-000-a-pill-drug

Anybody who sees this as acceptable lacks capacity for rational thought.

With GT3 you do not have a 100% chance of being less than LLOQ ie <15 at 4 weeks. The chances of being undetected are even less.

That's why I never do a qualitative test at 4 weeks - I do a QUANTITATIVE - coming back at 20 (when it was 1 million) is a lot more reassuring than coming back detected - which the majority of GT3s still are...

Here is what the SOF+DCV kinetics look like in both GT3 and GT1. Notice that GT1 responds faster but both are better than SOF+PEG+RBV. Note that 1.18 on the log scale is <15 and the line below that is the UND line.

Which geographical area are you in NZ?

Desiderata
Go placidly amid the noise and haste, and remember what peace there may be in silence.
As far as possible without surrender be on good terms with all persons.
Speak your truth quietly and clearly; and listen to others, even the dull and ignorant; they too have their story.
Avoid loud and aggressive persons, they are vexations to the spirit.
If you compare yourself with others, you may become vain and bitter;
for always there will be greater and lesser persons than yourself.

Enjoy your achievements as well as your plans.
Keep interested in your career, however humble; it is a real possession in the changing fortunes of time.
Exercise caution in your business affairs; for the world is full of trickery.
But let this not blind you to what virtue there is; many persons strive for high ideals;
and everywhere life is full of heroism.

Be yourself.
Especially, do not feign affection.
Neither be critical about love; for in the face of all aridity and disenchantment it is as perennial as the grass.

Take kindly the counsel of the years, gracefully surrendering the things of youth.
Nurture strength of spirit to shield you in sudden misfortune. But do not distress yourself with imaginings.
Many fears are born of fatigue and loneliness. Beyond a wholesome discipline, be gentle with yourself.

You are a child of the universe, no less than the trees and the stars;
you have a right to be here.
And whether or not it is clear to you, no doubt the universe is unfolding as it should.

Therefore be at peace with God, whatever you conceive Him to be,
and whatever your labors and aspirations, in the noisy confusion of life keep peace with your soul.
With all its sham, drudgery and broken dreams, it is still a beautiful world. Be careful. Strive to be happy.

© Max Ehrmann 1927