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Viewing 15 posts - 1,351 through 1,365 (of 1,968 total)
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  • in reply to: Double dose #14476
    dope-on-a-rope.jpgDr James
    • Guardian Angel
    • ★★★★★
    @fixhepc

    Do not skip the next dose.

    If side effect free take it at the normal time. If you think you are getting side effects and were dosing in the morning take the next dose in the evening, and the following one at lunch, and the the following back in the morning.


    YMMV

    in reply to: First Genotype 6 – Subtype 6a on this forum #14455
    dope-on-a-rope.jpgDr James
    • Guardian Angel
    • ★★★★★
    @fixhepc

    . So you think that you can buy 6 bottles and take all those pills then you will be cured ? It’s not that easy, if not we doctors don’t have to work any more !

    Without Ribavirin it is that easy for almost all patients taking DAA treatment.

    With Ribivirin, and with serious cirrhosis having a doctor to keep an eye on your bloods is important.


    YMMV

    in reply to: Beaches Treatment – Harvoni (Aus PBS) #14446
    dope-on-a-rope.jpgDr James
    • Guardian Angel
    • ★★★★★
    @fixhepc

    The Government certainly hasn’t made a lot of friends by cutting pathology/medicare rebates etc. I don’t begrudge for one minute the HCV drugs being made available here on the PBS. What I do object to is how they have prettied it all up and made out that EVERYONE will get the drugs. Not so from what I have heard……it will be triaged (and rightly so) and only the sickest will be able to access treatment. I am not an advocate for any Government and have very little respect for our politicians here in Australia, whichever one may be in power at any given time given they change so often :lol: It will be interesting to see how much money is available to our public hospitals to be able to provide the meds to their patients. Here in Bendigo there is a very very long waiting list for the treatment. I was still on a waiting list for 13 months just waiting for an appointment until I rang the Hospital to tell them to take me off the waiting list as I didn’t need their services. The list I was on was to get an appointment at the Medical Clinic who would then have to refer me to the liver clinic, and goodness knows how long that wait would have been.

    I am eternally grateful to James Freeman and his team in Tasmania and also the people on this Forum for the continued support. Not long now until I have my SVR 12 test……..

    Beaches I pretty much breezed through my treatment with Sof/Led….and yes if you drink plenty of water it certainly helps the headaches. My energy levels are so much better now too…..feel “different”…calm….and much more alert. All the best for the coming months… :)


    YMMV

    in reply to: To treat or not to treat: Acute HCV mono-infection #14426
    dope-on-a-rope.jpgDr James
    • Guardian Angel
    • ★★★★★
    @fixhepc

    You have a 25% chance of clearing virus yourself in the next 6 months and you are past the worst.

    With medication you have a 95%+ chance and you will be virus free within about 4 weeks and you only need 8 weeks treatment.

    It’s your choice. Waiting won’t kill you but you can get better sooner and chances are you WILL have to treat.


    YMMV

    in reply to: First Genotype 6 – Subtype 6a on this forum #14425
    dope-on-a-rope.jpgDr James
    • Guardian Angel
    • ★★★★★
    @fixhepc

    I would get the full 24 weeks and take that much of two DAAs. With the RIBA the benefits are probably marginal. 24 weeks Rx in both GT1 and GT3 seems to yield similar results with or without RIBA. Treating ASAP should be your priority. Getting the meds into pretty much anywhere is possible without the need for travel. Which country?


    YMMV

    in reply to: Help needed to initiate treatment. #14407
    dope-on-a-rope.jpgDr James
    • Guardian Angel
    • ★★★★★
    @fixhepc

    All the very best for your treatment…you are certainly in good hands.


    YMMV

    in reply to: Logging my experience also. #14382
    dope-on-a-rope.jpgDr James
    • Guardian Angel
    • ★★★★★
    @fixhepc

    Great news to hear…..I also never get tired of hearing of people’s wonderful progress :)


    YMMV

    in reply to: Different CAS numbers for Daclatasvir and Ledipasvir #14348
    dope-on-a-rope.jpgDr James
    • Guardian Angel
    • ★★★★★
    @fixhepc

    Canada allows medication for clinical trials to be imported. REDEMPTION is a clinical trial.


    YMMV

    in reply to: new member from south korea #14338
    dope-on-a-rope.jpgDr James
    • Guardian Angel
    • ★★★★★
    @fixhepc

    http://hcvadvocate.org/hepatitis/factsheets_pdf/viralload.pdf

    Just to confuse matters the conversion factor varies!

    ScreenShot2016-03-22at12.20.20am.png

    But <40 copies is roughly <10 or <15 - that is at the current technical limits.

    With COBAS Taqman you can have <15 (detected) and <15 (not detected - which really means <5 or <10 rather than absolute zero)


    YMMV

    in reply to: Blood Work Not So Good #14336
    dope-on-a-rope.jpgDr James
    • Guardian Angel
    • ★★★★★
    @fixhepc

    Hmm, I had Hep B in 1977 which cleared afaik, and had immunisation in 1990 required by a job I started. Could that really confuse the test?

    Probably not. The key thing with NOT being a carrier is that you develop surface Antibodies – carriers don’t, spontaneous clearers do and so do people who are immunised.

    About 5% of people who get immunised don’t develop surface antibodies – that would almost certainly be the same 5% who can’t clear the virus themselves. Not that immunisation is a bad thing because acute Hep B is a very unpleasant disease.


    YMMV

    in reply to: Ariel takes the Plunge #14330
    dope-on-a-rope.jpgDr James
    • Guardian Angel
    • ★★★★★
    @fixhepc

    Great news Ariel……nice tatt by the way :cheer:


    YMMV

    in reply to: Afraid to take the meds due to severe anxiety #14324
    dope-on-a-rope.jpgDr James
    • Guardian Angel
    • ★★★★★
    @fixhepc

    A simple explanation for blood in urine in a woman is around period time or urine infection. You want this to go away because if it does not it could be serious.

    I would take a watching brief on the others and see where they are at in a month or two or after treatment.

    Your cholesterol is a bit high. I would try a ketogenic diet (meats, fats and vegetables with low carbs and see what happens to it)

    CEA can be elevated in Ovarian and other cancers but if you read this:

    http://www.ncbi.nlm.nih.gov/pubmed/3148466

    You will note that it is a very poor screening test.


    YMMV

    in reply to: new member from south korea #14321
    dope-on-a-rope.jpgDr James
    • Guardian Angel
    • ★★★★★
    @fixhepc

    In the west IU/ml is the common thing we use (except where it is Hep B and both IU and copies get reported!!!!)

    Provided that the units are known conversion is easy.

    And regardless of units BIG NUMBER -> small number is good!


    YMMV

    in reply to: any one else have a co-infection with HVB? #14316
    dope-on-a-rope.jpgDr James
    • Guardian Angel
    • ★★★★★
    @fixhepc

    Thank you for this explanation. I will try to get my lab copies and compare them to this chart.

    It’s pretty simple:

    +ve Hep B surface Antigen = you currently have Hep B

    +ve Hep B surface Antibody = you don’t have Hep B and are immune to it (from vaccination or exposure)

    +ve Hep B core Antibody = you have been exposed to Hep B (so let’s you tell if positive surface antibody was immunisation or exposure)


    YMMV

    in reply to: Afraid to take the meds due to severe anxiety #14315
    dope-on-a-rope.jpgDr James
    • Guardian Angel
    • ★★★★★
    @fixhepc

    Hello Hope,

    The normal LFTs are good. The other things need to be looked at by a doctor – first totally ignoring the fact you have/had Hep C and then considering what if any role the medication might be playing.

    Haemochromatosis is an iron overload disease that can hide behind other liver diseases. It usually turns up in women after menopause because the blood loss each month keeps it under control.

    Nobody should have blood in their urine so this should be investigated.

    The ESR, CK and CEA are all somewhat non specific, but at the end of the day most people sit in the normal range for most tests and if you’re tests are outside those ranges it may just be you, but it may also be significant.

    Get a good doctor to look at it for you.


    YMMV

Viewing 15 posts - 1,351 through 1,365 (of 1,968 total)