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Viewing 15 posts - 1,411 through 1,425 (of 1,968 total)
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  • in reply to: EOT today! #13616
    dope-on-a-rope.jpgDr James
    • Guardian Angel
    • ★★★★★
    @fixhepc

    Great to finish treatment and hear that your side effects are subsiding. Good luck and can’t wait to hear of your SVR4 results. :)


    YMMV

    in reply to: BP while on Tx #13550
    dope-on-a-rope.jpgDr James
    • Guardian Angel
    • ★★★★★
    @fixhepc

    I had mine tested here at work a couple of weeks ago and it was 180/103!! I have one of those digital BP machines at home and it reads around 163/100 most of the time on my right arm and around 143/90 on my left arm, all over the place. I have never suffered with high blood pressure but it was actually how the Hep C was picked up. Very high at my annual health assessment at work last year so Doc followed on with blood tests etc. and here I am. Anyway my GP is not a great believer in the digital BP machines. It always reads high on his but when he takes it the old fashioned way it is always lower.

    It is something that I will need to address though and will be seeing my GP next week about it. I have no symptoms i.e. headaches etc. and feel well since finishing treatment.

    I have stopped using the BP monitor because it stresses me out :) :) :) :) :)


    YMMV

    dope-on-a-rope.jpgDr James
    • Guardian Angel
    • ★★★★★
    @fixhepc

    Sorafenib is a chemotherapy drug in the class of tyrosine kinase inhibitors and can hold HCC at bay for a while

    https://en.wikipedia.org/wiki/Sorafenib

    Cabozantinib is possibly better and under trial for HCC.

    I know a patient who was failing Sorafenib (almost looked like cure with the tumours calcifying), was refused entry into that Cabozantinib trial after a 2 week workup, and then started himself on a generic version.

    https://en.wikipedia.org/wiki/Cabozantinib

    He’s travelling ok. We wiped out his Hep C last year and his AFP has fallen from 2000+ to below 500 last time we looked. We are due to have a look see with CT this week.

    Like any single agent therapies resistance and breakthrough are likely, so it’s not a magic bullet like Sofosbuvir.


    YMMV

    in reply to: GT3: High SVR rates with Daclatasvir #13530
    dope-on-a-rope.jpgDr James
    • Guardian Angel
    • ★★★★★
    @fixhepc

    It is usual for the label to say 60 mg Daclatasvir. To get that 66 mg of Daclatasvir 2HCl is required. The use of the 2 HydoChloride salt relates to it being more soluble (and probably more stable) than the free base.

    If it was compounded you could check with whoever did it. If it’s box product they will have used 66 mg of the 2HCl.

    Some people who compounded their own medication did make the mistake of only using 60 mg of the Daclatascvir 2 HCl although for normal weight people that won’t make any difference. For people > 90 kg it might. We know from practical experience that 66 mg of Dac 2HCl is close to the toxic limit for people < 50 kg.


    YMMV

    in reply to: ‘In which LG seeks Redemption & makes new friends’ #13509
    dope-on-a-rope.jpgDr James
    • Guardian Angel
    • ★★★★★
    @fixhepc

    All the best for your daughter and you Ariel…….


    YMMV

    in reply to: The miracle of drinking lots of water #13481
    dope-on-a-rope.jpgDr James
    • Guardian Angel
    • ★★★★★
    @fixhepc

    Here’s what the Mayo Clinic suggests is an adequate intake of water:

    So how much fluid does the average, healthy adult living in a temperate climate need? The Institute of Medicine determined that an adequate intake (AI) for men is roughly about 13 cups (3 liters) of total beverages a day. The AI for women is about 9 cups (2.2 liters) of total beverages a day.

    http://www.mayoclinic.org/healthy-lifestyle/nutrition-and-healthy-eating/in-depth/water/art-20044256

    Anything over 4-5 litres is a worry as it can cause low sodium (which can be a real health hazard) and if it is driven by thirst can represent a sign of diabetes in particular.


    YMMV

    in reply to: FixHepC – Party Playlist #13480
    dope-on-a-rope.jpgDr James
    • Guardian Angel
    • ★★★★★
    @fixhepc

    Continuing the Australian theme. And I somehow rather fancy that I’d like to change with Clancy.

    [video]https://www.youtube.com/watch?v=qghnx1o5gJ4[/video]


    YMMV

    dope-on-a-rope.jpgDr James
    • Guardian Angel
    • ★★★★★
    @fixhepc

    Tomorrow I start with battle.

    Good luck! Please keep people posted over in the Patient section


    YMMV

    in reply to: Soooo…. #13460
    dope-on-a-rope.jpgDr James
    • Guardian Angel
    • ★★★★★
    @fixhepc

    Good luck Jaz……the three months goes pretty quickly doesn’t it……. :)


    YMMV

    in reply to: Young J the dragon slayer #13456
    dope-on-a-rope.jpgDr James
    • Guardian Angel
    • ★★★★★
    @fixhepc

    Wonderful news Cindi…….go J…..how awesome is he!!! :+1: :)

    I would have posted the dancing bananas but I don’t know where to find them!!


    YMMV

    in reply to: Official FOI FDA Side Effect Reports #13366
    dope-on-a-rope.jpgDr James
    • Guardian Angel
    • ★★★★★
    @fixhepc

    Edema

    If you add up all of these different ways of saying it you get to perhaps as much as 4.7%

    1.4% (11/759) Peripheral swelling
    0.8% (6/759) Ascites
    0.7% (5/759) Abdominal distension
    0.5% (4/759) Cardiac failure congestive
    0.5% (4/759) Fluid retention
    0.4% (3/759) Local swelling
    0.4% (3/759) Nephrotic syndrome


    YMMV

    in reply to: the patient poodle #13354
    dope-on-a-rope.jpgDr James
    • Guardian Angel
    • ★★★★★
    @fixhepc

    Hi Jill,

    You should get this checked out immediately.

    If you have – black, very stinky poo that is like liquid tar this is from bleeding high up in your gut – either from an ulcer or varices. This needs to be looked at urgently.

    Blood from low down is still red, but from higher up gets partly digested and goes black.

    If on the other hand you started taking iron tablets this will also make your poo black (but not stinky).


    YMMV

    in reply to: Been offered Sof/Riba, should I add daclatasvir? #13336
    dope-on-a-rope.jpgDr James
    • Guardian Angel
    • ★★★★★
    @fixhepc

    You did not follow my instructions to look at the AASLD guidelines as well and click the [Show Trials] button.


    YMMV

    in reply to: Emilio’s Place #13325
    dope-on-a-rope.jpgDr James
    • Guardian Angel
    • ★★★★★
    @fixhepc

    Hi Em,

    Under Medicare we can get 2 x quantitative and 4 x qualitative per patient, per year. I guess we must have hit one of those limits. I did not think we had.


    YMMV

    in reply to: Email Alert for PMs? #13289
    dope-on-a-rope.jpgDr James
    • Guardian Angel
    • ★★★★★
    @fixhepc

    At the moment you can have email notifications of PM.

    It defaults to no, don’t send email just in case somebody registered with a work email and don’t want to get emails.

    If you go to Private Messages there is a settings link bottom left. You can also have pop up alerts on if you want.


    YMMV

Viewing 15 posts - 1,411 through 1,425 (of 1,968 total)