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Great to finish treatment and hear that your side effects are subsiding. Good luck and can’t wait to hear of your SVR4 results.
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I had mine tested here at work a couple of weeks ago and it was 180/103!! I have one of those digital BP machines at home and it reads around 163/100 most of the time on my right arm and around 143/90 on my left arm, all over the place. I have never suffered with high blood pressure but it was actually how the Hep C was picked up. Very high at my annual health assessment at work last year so Doc followed on with blood tests etc. and here I am. Anyway my GP is not a great believer in the digital BP machines. It always reads high on his but when he takes it the old fashioned way it is always lower.
It is something that I will need to address though and will be seeing my GP next week about it. I have no symptoms i.e. headaches etc. and feel well since finishing treatment.
I have stopped using the BP monitor because it stresses me out
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8 March 2016 at 5:10 pm in reply to: Beacon Pharmaceuticals … Sof, Dac, Sof/Dac, Sof/Vel Combo #13537Sorafenib is a chemotherapy drug in the class of tyrosine kinase inhibitors and can hold HCC at bay for a while
https://en.wikipedia.org/wiki/Sorafenib
Cabozantinib is possibly better and under trial for HCC.
I know a patient who was failing Sorafenib (almost looked like cure with the tumours calcifying), was refused entry into that Cabozantinib trial after a 2 week workup, and then started himself on a generic version.
https://en.wikipedia.org/wiki/Cabozantinib
He’s travelling ok. We wiped out his Hep C last year and his AFP has fallen from 2000+ to below 500 last time we looked. We are due to have a look see with CT this week.
Like any single agent therapies resistance and breakthrough are likely, so it’s not a magic bullet like Sofosbuvir.
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It is usual for the label to say 60 mg Daclatasvir. To get that 66 mg of Daclatasvir 2HCl is required. The use of the 2 HydoChloride salt relates to it being more soluble (and probably more stable) than the free base.
If it was compounded you could check with whoever did it. If it’s box product they will have used 66 mg of the 2HCl.
Some people who compounded their own medication did make the mistake of only using 60 mg of the Daclatascvir 2 HCl although for normal weight people that won’t make any difference. For people > 90 kg it might. We know from practical experience that 66 mg of Dac 2HCl is close to the toxic limit for people < 50 kg.
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All the best for your daughter and you Ariel…….
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Here’s what the Mayo Clinic suggests is an adequate intake of water:
So how much fluid does the average, healthy adult living in a temperate climate need? The Institute of Medicine determined that an adequate intake (AI) for men is roughly about 13 cups (3 liters) of total beverages a day. The AI for women is about 9 cups (2.2 liters) of total beverages a day.
http://www.mayoclinic.org/healthy-lifestyle/nutrition-and-healthy-eating/in-depth/water/art-20044256
Anything over 4-5 litres is a worry as it can cause low sodium (which can be a real health hazard) and if it is driven by thirst can represent a sign of diabetes in particular.
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Continuing the Australian theme. And I somehow rather fancy that I’d like to change with Clancy.
[video]https://www.youtube.com/watch?v=qghnx1o5gJ4[/video]
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7 March 2016 at 4:23 pm in reply to: Beacon Pharmaceuticals … Sof, Dac, Sof/Dac, Sof/Vel Combo #13471Tomorrow I start with battle.
Good luck! Please keep people posted over in the Patient section
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Good luck Jaz……the three months goes pretty quickly doesn’t it…….
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Wonderful news Cindi…….go J…..how awesome is he!!!
I would have posted the dancing bananas but I don’t know where to find them!!
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Edema
If you add up all of these different ways of saying it you get to perhaps as much as 4.7%
1.4% (11/759) Peripheral swelling
0.8% (6/759) Ascites
0.7% (5/759) Abdominal distension
0.5% (4/759) Cardiac failure congestive
0.5% (4/759) Fluid retention
0.4% (3/759) Local swelling
0.4% (3/759) Nephrotic syndrome
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Hi Jill,
You should get this checked out immediately.
If you have – black, very stinky poo that is like liquid tar this is from bleeding high up in your gut – either from an ulcer or varices. This needs to be looked at urgently.
Blood from low down is still red, but from higher up gets partly digested and goes black.
If on the other hand you started taking iron tablets this will also make your poo black (but not stinky).
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You did not follow my instructions to look at the AASLD guidelines as well and click the [Show Trials] button.
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Hi Em,
Under Medicare we can get 2 x quantitative and 4 x qualitative per patient, per year. I guess we must have hit one of those limits. I did not think we had.
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At the moment you can have email notifications of PM.
It defaults to no, don’t send email just in case somebody registered with a work email and don’t want to get emails.
If you go to Private Messages there is a settings link bottom left. You can also have pop up alerts on if you want.
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