Forum Replies Created
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Hi all,
While it is indeed unfortunate that there have been cuts to some services in Australia, prioritisation of limited funding is always going to occur in any health system. As we have seen over many years, budgets and annual appropriations in all areas of government spending increase/decrease in line with the government of the day’s agenda and political pressures. And regardless of political persuasion there is never enough money for everything so prioritisation will always occur and the best we can hope/advocate is that those priorities are as humane and well targeted as possible.
Despite the fact that some of the recent health care cuts occurred at around the same time as funding for HCV DAA treatment was announced, I do not believe that these two are directly linked other than in the minds of the cynical with their own agendas to run and would suggest looking very, very closely at the motives of those that are presenting that view to you.
G3a since ’78 – Dx ’12 – F4 (2xHCC)
24wk Tx – PEG/Riba/Dac 2013 relapsed
24wk Tx – Generic Sof/Dac/Riba 2015/16 relapsed
16wk Tx – 12/01/17 -> 03/05/17 NS3/NS5a + Generic Sof
SVR7 – 22/06/17 UND
SRV12 – 27/07/17 UND
SVR24 – 26/10/17 UND
Looking good Em!
G3a since ’78 – Dx ’12 – F4 (2xHCC)
24wk Tx – PEG/Riba/Dac 2013 relapsed
24wk Tx – Generic Sof/Dac/Riba 2015/16 relapsed
16wk Tx – 12/01/17 -> 03/05/17 NS3/NS5a + Generic Sof
SVR7 – 22/06/17 UND
SRV12 – 27/07/17 UND
SVR24 – 26/10/17 UND
I had read that ALT/AST could reach several thousand in acute infections but never seen an example previously.
The good news is that your LFT now all seem to be tracking downwards and your VL is currently low. 
Clearance of Hep C of any genotype by any means does not appear to confer immunity due to the HCV virus’ ready ability to mutate allowing it to avoid your immune system.
Chronic HCV tends to be a slow acting and seemingly benign disease as seen by the number of us who did not become aware of infection until decades later. Having said that, it is causing damage the whole time you are infected so I would advise that earlier treatment of the chronic form is preferable to waiting but I’m not sure how well that translates to acute infection.
Below are the current AADSL/IDSA recommendations regarding Management of Acute HCV Infection.
http://www.hcvguidelines.org/full-report/management-acute-hcv-infection
G3a since ’78 – Dx ’12 – F4 (2xHCC)
24wk Tx – PEG/Riba/Dac 2013 relapsed
24wk Tx – Generic Sof/Dac/Riba 2015/16 relapsed
16wk Tx – 12/01/17 -> 03/05/17 NS3/NS5a + Generic Sof
SVR7 – 22/06/17 UND
SRV12 – 27/07/17 UND
SVR24 – 26/10/17 UND
Interesting report, but it is very much couched in terms of $ savings…..oh, and maybe some improved health outcomes and better treatment adherence?
It seems to me to sum up a lot that is wrong with our approach to health these days. Where is the study that says “What is the optimum treatment length by patient to minimise adverse effects and improve adherence……and maybe that will save some money too?”As a counter foil to the assumptions made in the report, I would suggest these drugs don’t have a particularly high cost but they do have an obscenely high price.
G3a since ’78 – Dx ’12 – F4 (2xHCC)
24wk Tx – PEG/Riba/Dac 2013 relapsed
24wk Tx – Generic Sof/Dac/Riba 2015/16 relapsed
16wk Tx – 12/01/17 -> 03/05/17 NS3/NS5a + Generic Sof
SVR7 – 22/06/17 UND
SRV12 – 27/07/17 UND
SVR24 – 26/10/17 UND
Nice numbers Jimmy! Congratulations.
G3a since ’78 – Dx ’12 – F4 (2xHCC)
24wk Tx – PEG/Riba/Dac 2013 relapsed
24wk Tx – Generic Sof/Dac/Riba 2015/16 relapsed
16wk Tx – 12/01/17 -> 03/05/17 NS3/NS5a + Generic Sof
SVR7 – 22/06/17 UND
SRV12 – 27/07/17 UND
SVR24 – 26/10/17 UND
Hi Dac,
These new DAA medications are different from the old treatments.There are no ‘stop treatment’ points if your viral load hasn’t dropped by a certain amount like there used to be with Peg/riba. Usually both slow and fast responders are recommended to continue treatment until completion of the full course unless there is some sort of adverse event which is rare.
Most of us get a 24 week prescription as 2 x 12 weeks but that is because the customs laws for most countries don’t allow import of more than 12 weeks medications at a time but it sounds like that is not the situation for you in Vietnam? As the others say, it would be useful to understand your hepatologist’s reasons for her recommendation.
G3a since ’78 – Dx ’12 – F4 (2xHCC)
24wk Tx – PEG/Riba/Dac 2013 relapsed
24wk Tx – Generic Sof/Dac/Riba 2015/16 relapsed
16wk Tx – 12/01/17 -> 03/05/17 NS3/NS5a + Generic Sof
SVR7 – 22/06/17 UND
SRV12 – 27/07/17 UND
SVR24 – 26/10/17 UND
Life!
Best wishes for your SVR12 soon.
G3a since ’78 – Dx ’12 – F4 (2xHCC)
24wk Tx – PEG/Riba/Dac 2013 relapsed
24wk Tx – Generic Sof/Dac/Riba 2015/16 relapsed
16wk Tx – 12/01/17 -> 03/05/17 NS3/NS5a + Generic Sof
SVR7 – 22/06/17 UND
SRV12 – 27/07/17 UND
SVR24 – 26/10/17 UND
Hi Leoshi,
Great news to hear that you are undetected after 4 weeks.
….and very few sides too!
G3a since ’78 – Dx ’12 – F4 (2xHCC)
24wk Tx – PEG/Riba/Dac 2013 relapsed
24wk Tx – Generic Sof/Dac/Riba 2015/16 relapsed
16wk Tx – 12/01/17 -> 03/05/17 NS3/NS5a + Generic Sof
SVR7 – 22/06/17 UND
SRV12 – 27/07/17 UND
SVR24 – 26/10/17 UND
Yes, or something like ‘Hep C Medication Buyers Club’ or similar so that search engines pick up the key words people are likely to use when looking for something like this.
Edit: or ‘Hepatitis C Medicine Buyers Club’ – we get too used to abbreviations and terms that the general public may not use when googling.
G3a since ’78 – Dx ’12 – F4 (2xHCC)
24wk Tx – PEG/Riba/Dac 2013 relapsed
24wk Tx – Generic Sof/Dac/Riba 2015/16 relapsed
16wk Tx – 12/01/17 -> 03/05/17 NS3/NS5a + Generic Sof
SVR7 – 22/06/17 UND
SRV12 – 27/07/17 UND
SVR24 – 26/10/17 UND
Hi Hope,
Not only were you able to organise the medication you need when your doctor couldn’t but now you’ve got her monitoring your treatment……you definitely sound like a very smart, intelligent woman to me.
G3a since ’78 – Dx ’12 – F4 (2xHCC)
24wk Tx – PEG/Riba/Dac 2013 relapsed
24wk Tx – Generic Sof/Dac/Riba 2015/16 relapsed
16wk Tx – 12/01/17 -> 03/05/17 NS3/NS5a + Generic Sof
SVR7 – 22/06/17 UND
SRV12 – 27/07/17 UND
SVR24 – 26/10/17 UND
”jay wrote:And one more question for Dr. Freeman.
In Korea, It seems that the minimum VL the blood test machine can detect is 40copies/ML.
Does blood test machine in AUS detect lower than 40 copies/ML?
is <41copies/ML same as UND?
thanks in advance
Hi jay kim,
Do you know which test is being used to give you 40 copies/ML? If you do then the minimum level can be converted to iu/ML.
G3a since ’78 – Dx ’12 – F4 (2xHCC)
24wk Tx – PEG/Riba/Dac 2013 relapsed
24wk Tx – Generic Sof/Dac/Riba 2015/16 relapsed
16wk Tx – 12/01/17 -> 03/05/17 NS3/NS5a + Generic Sof
SVR7 – 22/06/17 UND
SRV12 – 27/07/17 UND
SVR24 – 26/10/17 UND
Thank you for clarifying.
G3a since ’78 – Dx ’12 – F4 (2xHCC)
24wk Tx – PEG/Riba/Dac 2013 relapsed
24wk Tx – Generic Sof/Dac/Riba 2015/16 relapsed
16wk Tx – 12/01/17 -> 03/05/17 NS3/NS5a + Generic Sof
SVR7 – 22/06/17 UND
SRV12 – 27/07/17 UND
SVR24 – 26/10/17 UND
Hi Hope,
Great to hear that your liver functions are back to normal, that’s a good sign that the meds are doing their job. Look forward to hearing of your VL results when you get them, I’m sure they will also be good news.
The other results don’t sound directly related to the treatment and you should discuss with a doctor whether they need further investigation so you aren’t worrying about them.It sounds like you are handling any side effects without too many concerns which is good news.
I wouldn’t be too worried about any issues not clearing up yet, you have had hep for a long time so it is unlikely that all the symptoms will just disappear immediately. And some may not be totally related but once you get rid of the virus you will be a lot healthier and can then focus on anything that is left.Wishing you a great VL result.
G3a since ’78 – Dx ’12 – F4 (2xHCC)
24wk Tx – PEG/Riba/Dac 2013 relapsed
24wk Tx – Generic Sof/Dac/Riba 2015/16 relapsed
16wk Tx – 12/01/17 -> 03/05/17 NS3/NS5a + Generic Sof
SVR7 – 22/06/17 UND
SRV12 – 27/07/17 UND
SVR24 – 26/10/17 UND
Hi Radtek,
If you check my post on the previous page, I was greedily
eating 5-6 big handfuls of grapes per day. The effect was mild but noticeable. I don’t know how many raisins your Raisin Bran has in it but doubt it would be anywhere near the level I was eating. If you are still worried eat it at the opposite end of the day from the meds and maybe think about alternating daily with a different cereal/bran that doesn’t have raisins.
G3a since ’78 – Dx ’12 – F4 (2xHCC)
24wk Tx – PEG/Riba/Dac 2013 relapsed
24wk Tx – Generic Sof/Dac/Riba 2015/16 relapsed
16wk Tx – 12/01/17 -> 03/05/17 NS3/NS5a + Generic Sof
SVR7 – 22/06/17 UND
SRV12 – 27/07/17 UND
SVR24 – 26/10/17 UND
Hi and welcome,
As Chapel says, but in a bit more detail:
Put in GT 1a
F4
Failed Interferon Riba
No to Harvoni CI (assuming you don’t meet any of listed conditions/meds)
Aust guidelines
Then your numbers for platelets, weight, eGFRCalculate
Scroll down and press [Show Trials]
You can then change the guidelines to see what EASL/AASLD say in their guidelines.
Your options for meds will most likely be Sofosbuvir, Ledipasvir, Daclatasvir and Ribavirin so focus on the best percentage options for those across the various recommendations and trials that inform them. Most likely it will be Sof/Led (Harvoni) for 24 weeks +riba.
Script should be for 12 weeks/84 days with “one repeat” assuming the recommendation is for 24 weeks. I believe you should still be able to pay for the repeat when you need it to be shipped but check with help@fixhepc.com
Was the U/S scan just a routine check up? I suspect your GP will get the U/S results pretty quickly and well before you get the meds anyway but would wait till he has it to actually commence treatment.
G3a since ’78 – Dx ’12 – F4 (2xHCC)
24wk Tx – PEG/Riba/Dac 2013 relapsed
24wk Tx – Generic Sof/Dac/Riba 2015/16 relapsed
16wk Tx – 12/01/17 -> 03/05/17 NS3/NS5a + Generic Sof
SVR7 – 22/06/17 UND
SRV12 – 27/07/17 UND
SVR24 – 26/10/17 UND
