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Just heard back from the clinic with my 12 week VL results, big drum roll………..
Not Detected!!!
A big “Thank You!” to Dr James and all of the people behind the scenes at FixHepC who made this possible.
G3a since ’78 – Dx ’12 – F4 (2xHCC)
24wk Tx – PEG/Riba/Dac 2013 relapsed
24wk Tx – Generic Sof/Dac/Riba 2015/16 relapsed
16wk Tx – 12/01/17 -> 03/05/17 NS3/NS5a + Generic Sof
SVR7 – 22/06/17 UND
SRV12 – 27/07/17 UND
SVR24 – 26/10/17 UND
Congratulations on being undetected, Lizzi!
G3a since ’78 – Dx ’12 – F4 (2xHCC)
24wk Tx – PEG/Riba/Dac 2013 relapsed
24wk Tx – Generic Sof/Dac/Riba 2015/16 relapsed
16wk Tx – 12/01/17 -> 03/05/17 NS3/NS5a + Generic Sof
SVR7 – 22/06/17 UND
SRV12 – 27/07/17 UND
SVR24 – 26/10/17 UND
Congratulations Chejai!
G3a since ’78 – Dx ’12 – F4 (2xHCC)
24wk Tx – PEG/Riba/Dac 2013 relapsed
24wk Tx – Generic Sof/Dac/Riba 2015/16 relapsed
16wk Tx – 12/01/17 -> 03/05/17 NS3/NS5a + Generic Sof
SVR7 – 22/06/17 UND
SRV12 – 27/07/17 UND
SVR24 – 26/10/17 UND
Congratulations Splitdog.
Onward and upward!
G3a since ’78 – Dx ’12 – F4 (2xHCC)
24wk Tx – PEG/Riba/Dac 2013 relapsed
24wk Tx – Generic Sof/Dac/Riba 2015/16 relapsed
16wk Tx – 12/01/17 -> 03/05/17 NS3/NS5a + Generic Sof
SVR7 – 22/06/17 UND
SRV12 – 27/07/17 UND
SVR24 – 26/10/17 UND
Great news Debs!
G3a since ’78 – Dx ’12 – F4 (2xHCC)
24wk Tx – PEG/Riba/Dac 2013 relapsed
24wk Tx – Generic Sof/Dac/Riba 2015/16 relapsed
16wk Tx – 12/01/17 -> 03/05/17 NS3/NS5a + Generic Sof
SVR7 – 22/06/17 UND
SRV12 – 27/07/17 UND
SVR24 – 26/10/17 UND
Must be a great feeling.
Congratulations!
G3a since ’78 – Dx ’12 – F4 (2xHCC)
24wk Tx – PEG/Riba/Dac 2013 relapsed
24wk Tx – Generic Sof/Dac/Riba 2015/16 relapsed
16wk Tx – 12/01/17 -> 03/05/17 NS3/NS5a + Generic Sof
SVR7 – 22/06/17 UND
SRV12 – 27/07/17 UND
SVR24 – 26/10/17 UND
A UK study has reviewed data from other trials to investigate benefits of increased coffee consumption in relation to cirrhosis risk. A significant participant number of >400k and shows a strong correlation between increasing coffee consumption by 2 cups per day and reduced risk.
http://hepatitiscnewdrugs.blogspot.com.au/2016/02/coffee-consumption-and-risk-of-cirrhosis.html
…….off to grind some more beans!
G3a since ’78 – Dx ’12 – F4 (2xHCC)
24wk Tx – PEG/Riba/Dac 2013 relapsed
24wk Tx – Generic Sof/Dac/Riba 2015/16 relapsed
16wk Tx – 12/01/17 -> 03/05/17 NS3/NS5a + Generic Sof
SVR7 – 22/06/17 UND
SRV12 – 27/07/17 UND
SVR24 – 26/10/17 UND
Hi Ken,
Seems to work for me too! My experience has been much like yours in that keeping well hydrated seems to make a big difference to the sides particularly things like headaches which I can feel fading away as I increase my water levels. I don’t drink quite as much water as you but at least 2.5 – 3 litres plus other fluids such as coffee, juices, etc. (plus I eat a lot of fruit) but that increases a lot in hot weather.
What I do is drink enough water to be just this side of being really annoyed by having to pee all the time, so if I’m going every hour or so I figure that is acceptable from both a comfort and hydration level.
G3a since ’78 – Dx ’12 – F4 (2xHCC)
24wk Tx – PEG/Riba/Dac 2013 relapsed
24wk Tx – Generic Sof/Dac/Riba 2015/16 relapsed
16wk Tx – 12/01/17 -> 03/05/17 NS3/NS5a + Generic Sof
SVR7 – 22/06/17 UND
SRV12 – 27/07/17 UND
SVR24 – 26/10/17 UND
Hi Demian,
I’m sure either Incepta or the Redemption Trials sponsored through FixHepC can supply to Romania. Both are reliable, trusted sources.
Incepta Pharmacueticals can be contacted via the email address that Greedfighter gave you above or by private chat and private message on this site with member Parvez (alimul and Parvez are the same person)
Redemption Trials information and contacts can be found in below link on this site:
http://fixhepc.com/forum/redemption/203-so-what-are-the-redemption-trials.html
G3a since ’78 – Dx ’12 – F4 (2xHCC)
24wk Tx – PEG/Riba/Dac 2013 relapsed
24wk Tx – Generic Sof/Dac/Riba 2015/16 relapsed
16wk Tx – 12/01/17 -> 03/05/17 NS3/NS5a + Generic Sof
SVR7 – 22/06/17 UND
SRV12 – 27/07/17 UND
SVR24 – 26/10/17 UND
Curious to see if Mike knows…..
Notification already sent, CC2B.
I can understand the licenced companies preventing shipment but this appears from Greg’s comments to be blocking by customs? As India doesn’t recognise the Gilead patents why is this happening? Hopefully it gets challenged in their courts.
G3a since ’78 – Dx ’12 – F4 (2xHCC)
24wk Tx – PEG/Riba/Dac 2013 relapsed
24wk Tx – Generic Sof/Dac/Riba 2015/16 relapsed
16wk Tx – 12/01/17 -> 03/05/17 NS3/NS5a + Generic Sof
SVR7 – 22/06/17 UND
SRV12 – 27/07/17 UND
SVR24 – 26/10/17 UND
Hi Ariel,
Don’t worry about the doctor asking those questions, it is SOP and not a reflection on you. I used to get that too, but over the last four years have built a pretty good relationship with my specialist (and other clinic staff) due to regular visits so he obviously no longer feels need to check those aspects. To be honest I’d rather answer those questions and not need the ten or so visits I had in last 12 months.
I understand how you probably feel that you are treated as just being a number, I think some of it is self preservation on the part of the staff, though some are definitely better than others at bedside manner.
I’m sure most staff of all the clinics are glad that they will have something better to offer from 1st March but will be looking at the coming workload and how they prioritise with some trepidation.Great news about granuloma! It’s really nice, and builds confidence in the Tx when others start to notice the difference, doesn’t it?
G3a since ’78 – Dx ’12 – F4 (2xHCC)
24wk Tx – PEG/Riba/Dac 2013 relapsed
24wk Tx – Generic Sof/Dac/Riba 2015/16 relapsed
16wk Tx – 12/01/17 -> 03/05/17 NS3/NS5a + Generic Sof
SVR7 – 22/06/17 UND
SRV12 – 27/07/17 UND
SVR24 – 26/10/17 UND
Browny wrote:Hec P RNA NAA was 6.4×10^5 and is now 15
I don’t really understand the results very well …. (lol)!
Hi Browny,
The log figure means the first number times ten by the number of times the little number beside the ten shows. So in your case 6.4 multiplied by ten, five times or 6.4 x 10 x 10 x 10 x10 x10 = 640,000 In other words, your pretreatment test was 640,000.
I suspect your new result is probably less than 15, maybe shown as <15 just because 15 is a common cutoff point for a lot of these tests. Whichever it is, that's a good result for F3-4 at 4 weeks. :+1: :)
G3a since ’78 – Dx ’12 – F4 (2xHCC)
24wk Tx – PEG/Riba/Dac 2013 relapsed
24wk Tx – Generic Sof/Dac/Riba 2015/16 relapsed
16wk Tx – 12/01/17 -> 03/05/17 NS3/NS5a + Generic Sof
SVR7 – 22/06/17 UND
SRV12 – 27/07/17 UND
SVR24 – 26/10/17 UND
Hi Ariel,
I’m no doctor but those tests all look fine to me, well within range. No AST test? Or was that on another page maybe?
The old regime of four week testing being critical went out the window with Peg/Riba but you would have aced it anyway with those results. These days the testing just confirms the meds are working and so gives you confidence.
Your viral load was detected but at below a level which they could measure, so ‘not quite’ undetected but with your F0 results I’m sure you will be at 8 weeks. She probably just wanted to wag a finger at you about drinking, some people are like that.
G3a since ’78 – Dx ’12 – F4 (2xHCC)
24wk Tx – PEG/Riba/Dac 2013 relapsed
24wk Tx – Generic Sof/Dac/Riba 2015/16 relapsed
16wk Tx – 12/01/17 -> 03/05/17 NS3/NS5a + Generic Sof
SVR7 – 22/06/17 UND
SRV12 – 27/07/17 UND
SVR24 – 26/10/17 UND
I’m not sure of general availability of testing outside of research/trial situations ATM but certainly possible depending on where and when. And even if some resistance has developed it will depend on the resistance sites as to how strong the effect is, so as far as I understand longer treatment may still produce good results.
G3a since ’78 – Dx ’12 – F4 (2xHCC)
24wk Tx – PEG/Riba/Dac 2013 relapsed
24wk Tx – Generic Sof/Dac/Riba 2015/16 relapsed
16wk Tx – 12/01/17 -> 03/05/17 NS3/NS5a + Generic Sof
SVR7 – 22/06/17 UND
SRV12 – 27/07/17 UND
SVR24 – 26/10/17 UND
Hi Johnboy,
It will depend on why you relapsed. So length of original treatment, fibrosis, any resistance to Dac developed, etc.
So original Tx of 12 weeks with no resistance developed would likely indicate retreating with 24 weeks if no peg and/or riba was acceptable. Or as you say, wait to see Velpatasvir availability and results.
If NS5a resistance to Dac was developed then wait and look at Velpatasvir when available assuming that your HCV resistance path is suited to its use. Or another new DAA as available, maybe something other than NS5a inhibition?
So based on individual case I suspect but as Sir says the future looks bright.
G3a since ’78 – Dx ’12 – F4 (2xHCC)
24wk Tx – PEG/Riba/Dac 2013 relapsed
24wk Tx – Generic Sof/Dac/Riba 2015/16 relapsed
16wk Tx – 12/01/17 -> 03/05/17 NS3/NS5a + Generic Sof
SVR7 – 22/06/17 UND
SRV12 – 27/07/17 UND
SVR24 – 26/10/17 UND
