Hmmm, both threads pulled. I’m still there for now. Tap fingers waiting to see if anything at all survives.

Bored? Haven’t had such fun in years. Read counters are spinning their dials. Just hoping a few of the people there realise that something is happening and start looking outside of Joy to the Delete.

Going to give it a while to see what happens.

There are Cindi, all we can do is hope. And ask what seem like reasonable questions to me.

Cindi,

That’s such good news to hear. So happy for you both.

G

“people who don’t seem to have the patience to go through what others have . . “

I find this comment telling about the person involved, or am I wrong in reading an over controlling ‘you must take your punishment like I had to’ attitude into it?

I suspect in this case all we can do is work to grow the public information about generics enough that people from that site become aware of the opportunities through more open public media (big newsy things) and migrate to somewhere where they can get emotional support and valid information.

G

Single units, both 8-10mm. S5 Resect – clean. S? RFAblation – radiologist pleased & CT last week with results at monitoring visit next week and no urgent calls so sounds good. Pretty much the same comments as you. Failed Peg/riba 2013 so close monitoring. Bloods went silly this year so u/s upped to MRI and CT and confirmed #1. Came out clean so thought okay. First 3mth scan in Sept picked up the other one. Found Greg then the club the same week as doc called me and here I am.

G

To answer 2b’s first question in laymans terms. Yes, one of the traits of the HCV virus is that as it replicates it creates lots mutations some of which are different enough in structure that the DAA can no longer lock on to the receptor parts on the virus that it would normally use to block replication. So you then have DAA resistant virions in you which sounds bad; the good news here is that like most mutations they tend to be weak in some way and that particularly applies to their ability to reproduce or in this case replicate. So they tend to die out naturally or your immune and garbage disposal systems cleans them up. The problem occurs when a mutation occurs that is resistant to a DAA and can replicate reasonably well. Then because Hep c replicates so fast you soon end up with an infection with some immunity to the DAA and also other DAAs that work on the same receptor. This immunity will apply to whichever receptor that particular DAA works on so to re-treat you need to preferably use a DAA that works on other receptors if available for the genotype or hit it longer and harder and/or add riba or all of the above. It isn’t a huge problem but is the cause of some of those few percent who are non responders or relapsers.

Hope that makes sense.

The second answer is…..too bloody long! Or, I have no idea so hope someone else has an answer.

Great news Paul!

It must be a relief to get that call.