Harvoni generic and pregnancy - FixHepC

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24 May 2016 at 2:29 pm #17695
simone
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- Acolyte
@simone
hi there, another query.

having been trying to become a father for quite some time, and nearly succeded, i am now concerned about my new meds. would they hinder my chances? or rather, could it be dangerous to the foetus and mother?

previously, when interferon was involved, i was told to have protected sex. now apparently there are no risks. anybody WITH DIRECT EXPERIENCE could give me feedback please?

thank you

Rere S.
25 May 2016 at 2:35 am #17718
Dr James
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- Guardian Angel
@fixhepc
With any new drug many impacts are unknown.

If you search for “sofosbuvir semen” on Google you will only find 2 results.

Sofosbuvir was previously known as PSI-7977 and GSI-7977 so you should also search for

pharmasset psi-7977 semen

gilead gsi-7977 semen

The last search yields this result: http://www.natap.org/2014/EASL/nejmoa1316366_protocol.pdf however the excretion in semen refers to Ribavirin.

Anyway in the absence of documentation saying it’s not in semen you would be safest to refrain from trying to have children during treatment. The logic for how long to wait after treatment see:

http://fixhepc.com/forum/experts-corner/872-how-long-should-i-wait-after-treatment-before-getting-pregnant.html

YMMV
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