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Harvoni vs Daklinza 5 years 9 months ago #23764

  • DrJames
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Recently we saw SVR rates of 91-92% reported for Harvoni in a big (4200+) group of patients treated by the US VA.

fixhepc.com/forum/experts-corner/1316-ha...va-study-n-4365.html

At CROI 2017 further results from the German GECCO study were reported, and if you have a look at figure 3 there is a strong suggestion that Sofosbuvir + Daclatasvir is a better choice for GT1 than Harvoni. We have seen similar results with generics.

www.croiconference.org/sites/default/files/posters-2016/584.pdf

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YMMV
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Last edit: by DrJames.

Harvoni vs Daklinza 5 years 9 months ago #23883

I support this by my own experience as a previous GT1a that extended with Sofosbuvir/Daclatasvir . :+1:
GT1a Dec14 F2/8.7 VL 900000-2.5M
Jan16 Hepcivir-L MonkMed/Redemption
Baseline: VL 913575 Alt 76 Platelets low
Wk2 VL1157 Alt 23
DET Wk 8 VL 32 Alt19 'In the slow lane'
June16 Fibro 5.7 F0/1 LIF 1.5
Wk 11 VL<12 Alt 13 Det/Unq
Extending tx 12 wks Mylan Sofo/Dac MonkMed
Wk 14 VL <12 Det/Unq
Wk 16 VL UNDETECTED
Wk 22 + 4 Wks Sunprevir FixHepC
Wk 24 UNDETECTED Alt 13
Wk 12 post tx SVR12 Wk 26 SVR24
Thank-you Tim, Dr Debasis @ MonkMed & Dr Freeman @ Fix HepC
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