emo Sofosvel (velpatasvir)

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5 years 10 months ago #22181

Thanks, everybody. I woke up and read these responses and got a little choked up. Thank you all.


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Genotype 3
VL 4,100,000
ALT 101 AST 71
Treatment Naive
Started Sof/Dac Jan 12, 2016
VL= <15 4 weeks in. AST/ALT normal.
VL=UNDETECTED 8 weeks in.
SVR4= Virus back. 3,300,000

Started generic Epclusa Sep. 23, 2017

4 weeks in <15 *Detected.
12 weeks in <15 *Not Detected.
16 weeks in <15 *Not Detected.
Finished 24 weeks treatment 3-17-18
SVR5 <15 Not Detected.
SVR 20 <15 Not Detected.
SVR 44 <15 Not Detected.

Thank you Jesus.
Thank you Dr. James
The following user(s) said Thank You: DrJames, tweakmax, LondonGirl, coral, rohcvfighter, fitz

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5 years 9 months ago #22509

Summary of trials data to help one compare sof/vel with other effective treatments
congress-ph.ru/common/htdocs/upload/fm/g.../2016/prez/1-3-2.pdf
www.natap.org/2016/AASLD/AASLD.htm

In-vivo resistance analysis (sof/vel, all phase III trials).
Enough statistics for some genotypes.
www.natap.org/2016/EASL/EASL_15.htm


Gen 1b
VL pre treatment 29000 ME/ml
AST 32 ALT 94, F0
Started treatment 13 January 2017
Generic sofosbuvir/velpatasvir (Incepta)
VL 9 days into treatment <300 (undetected)
AST 13.8 ALT 22
Side effects: mild dehydration, not a problem at all if I drink water at night, nothing to worry about
Diet and gastric ph are very important with velpatasvir. One must think what and when to eat to keep gastric pH low. Side effects disappeared 2 weeks after, unless I ate anything < 4hrs before the pill. SVR60.
Last Edit: 5 years 8 months ago by vitrus.
The following user(s) said Thank You: fitz

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5 years 9 months ago #22622

Rapid Virological Response reported in 1 case.
hepcfriends.activeboard.com/t62645983/epclusers-corner/
One should drink lots of lots of water with velpatasvir to avoid dehydration and take pills at one time of the day. Side effects are said to be more than manageable, mild headaches and fatigue, water helps.


Gen 1b
VL pre treatment 29000 ME/ml
AST 32 ALT 94, F0
Started treatment 13 January 2017
Generic sofosbuvir/velpatasvir (Incepta)
VL 9 days into treatment <300 (undetected)
AST 13.8 ALT 22
Side effects: mild dehydration, not a problem at all if I drink water at night, nothing to worry about
Diet and gastric ph are very important with velpatasvir. One must think what and when to eat to keep gastric pH low. Side effects disappeared 2 weeks after, unless I ate anything < 4hrs before the pill. SVR60.
Last Edit: 5 years 8 months ago by vitrus.

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