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Extending TX +4 or 6 weeks 7 years 11 months ago #14377

  • MtGoat
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Yesterday I read a post about 3a relapses, saw Dr James' response & saw on some related posts that a few extra weeks would be a good idea. Just as I was on a five day count down to EOT (12 weeks). Anyway, after losing sleep last night, I went ahead and ordered a 6 week supply. The thing is, I'll run out of what I have. There will be about a 4 day lapse of TX. Does that seem terrible to anyone? Has anyone else missed a few days during TX?
Thanks for any feedback.
Cheers
3a for 35 years
Dx 1996, tx naive, ALT 46 AST 38 VL 140K
Started Sof/Dac 1/23/16
Kingswood generics AUS
2/19/16 4wk lab HCV Undetected ALT 14 AST 19
EOT 6/1/2016
TX was 18 wks (w/some 1/2 doses & 1 skip dose after 11 wks
while waiting for +6 wks to arrive)
SVR4 6/30/16
SVR12
SVR24 Redeemed

Extending TX +4 or 6 weeks 7 years 11 months ago #14378

  • Gaj
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Hi MtGoat,

How are you shipping? Would FedEx door to door help shorten timing? I can usually get US to Aust in about 5-6 days including w/ends.
G3a since '78 - Dx '12 - F4 (2xHCC)
24wk Tx - PEG/Riba/Dac 2013 relapsed
24wk Tx - Generic Sof/Dac/Riba 2015/16 relapsed
16wk Tx - 12/01/17 -> 03/05/17 NS3/NS5a + Generic Sof
SVR7 - 22/06/17 UND
SRV12 - 27/07/17 UND
SVR24 - 26/10/17 UND
:cheer: :cheer: :cheer:

Extending TX +4 or 6 weeks 7 years 11 months ago #14379

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Hey Gaj, I think it'll only take 5 or 6 days, but I won't be returning from a trip for a couple days after that. I've already laid money down for the trip & leaving in 3 days. I could take what I have left every other day. But, just hard to know what'd be best.
Cheers
3a for 35 years
Dx 1996, tx naive, ALT 46 AST 38 VL 140K
Started Sof/Dac 1/23/16
Kingswood generics AUS
2/19/16 4wk lab HCV Undetected ALT 14 AST 19
EOT 6/1/2016
TX was 18 wks (w/some 1/2 doses & 1 skip dose after 11 wks
while waiting for +6 wks to arrive)
SVR4 6/30/16
SVR12
SVR24 Redeemed
The following user(s) said Thank You: Gaj

Extending TX +4 or 6 weeks 7 years 11 months ago #14381

Why not spread your remaining doses out and take them every 48 hrs. The meds have a 1/2 life of 27 hrs which means they stay in our system for many weeks at a reduced dosage.

Or split them and take 1/2 per day.

cheers
Two time relapser.

SVR 4 achieved 12/16 at last
SVR 12 achieved 22/02/2017 The Bastard has been defeated :):):)

GT 3 - about 28 yrs with HCV
The following user(s) said Thank You: LondonGirl, MtGoat

Extending TX +4 or 6 weeks 7 years 11 months ago #14405

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Why not spread your remaining doses out and take them every 48 hrs. The meds have a 1/2 life of 27 hrs which means they stay in our system for many weeks at a reduced dosage.


Rationing is definitely the way to go, but rather than every other day (and provided you're up for it) if you have a shortfall the best way would be to open the capsules/split the tablets in 1/2 and take 1/2 a dose each day. Not as good as a full dose every day, but much better than a complete break. Failing that every 48 hours is a good option.
YMMV
The following user(s) said Thank You: LondonGirl, mgalbrai

Extending TX +4 or 6 weeks 7 years 11 months ago #14408

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Dr. James,
Thank you very much. I was hoping you,d advise. Much appreciated!
And thanks to you too Paul.
Cheers
3a for 35 years
Dx 1996, tx naive, ALT 46 AST 38 VL 140K
Started Sof/Dac 1/23/16
Kingswood generics AUS
2/19/16 4wk lab HCV Undetected ALT 14 AST 19
EOT 6/1/2016
TX was 18 wks (w/some 1/2 doses & 1 skip dose after 11 wks
while waiting for +6 wks to arrive)
SVR4 6/30/16
SVR12
SVR24 Redeemed
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