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generic harvoni in india 7 years 3 months ago #1236

GT1a Dec14 F2/8.7 VL 900000-2.5M
Jan16 Hepcivir-L MonkMed/Redemption
Baseline: VL 913575 Alt 76 Platelets low
Wk2 VL1157 Alt 23
DET Wk 8 VL 32 Alt19 'In the slow lane'
June16 Fibro 5.7 F0/1 LIF 1.5
Wk 11 VL<12 Alt 13 Det/Unq
Extending tx 12 wks Mylan Sofo/Dac MonkMed
Wk 14 VL <12 Det/Unq
Wk 16 VL UNDETECTED
Wk 22 + 4 Wks Sunprevir FixHepC
Wk 24 UNDETECTED Alt 13
Wk 12 post tx SVR12 Wk 26 SVR24
Thank-you Tim, Dr Debasis @ MonkMed & Dr Freeman @ Fix HepC
The following user(s) said Thank You: Alsdad

generic harvoni in india 7 years 3 months ago #1239

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"Information has emerged that US Ambassador to the World Trade Organization, Michael Punke, met with representatives of 15 LDCs last Friday in Geneva, where he noted that the US could not agree to an indefinite exemption due to pressure from some US stakeholders who are upset with the US government’s intellectual property concessions on the recently-completed Trans-Pacific Partnership trade agreement."

And there, in one sentence, is pure, feral corporate greed applying pressure on it's government for all to see. :sick:
The following user(s) said Thank You: pat1

generic harvoni in india 7 years 3 months ago #1240

:ohmy: :angry:
GT1a Dec14 F2/8.7 VL 900000-2.5M
Jan16 Hepcivir-L MonkMed/Redemption
Baseline: VL 913575 Alt 76 Platelets low
Wk2 VL1157 Alt 23
DET Wk 8 VL 32 Alt19 'In the slow lane'
June16 Fibro 5.7 F0/1 LIF 1.5
Wk 11 VL<12 Alt 13 Det/Unq
Extending tx 12 wks Mylan Sofo/Dac MonkMed
Wk 14 VL <12 Det/Unq
Wk 16 VL UNDETECTED
Wk 22 + 4 Wks Sunprevir FixHepC
Wk 24 UNDETECTED Alt 13
Wk 12 post tx SVR12 Wk 26 SVR24
Thank-you Tim, Dr Debasis @ MonkMed & Dr Freeman @ Fix HepC

generic harvoni in india 7 years 3 months ago #1268

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Gilead's APIs are made in Jordan. The tablets are made in Ireland.
YMMV

generic harvoni in india 7 years 3 months ago #1269

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LondonGirl wrote: What does this mean Emilio? Impossible to receive by mail?


Sorry LG I saw this one on my phone today and didn't realised I hadn't responded. Yeah well they may try but probably can only stifle. Most likely put the pressure onto Indian Pharma to only sell to Indian citizens etc. Who knows? But the Indians will always find a way to get it out to the masses and Gilead know this and hence the delay in production in India. Em
Geno 1b F2/3 snce early 80s. Treated in 2008_9 for 63 weeks on INF/Riba. Commence Sof/Dac on 6 October 2015 and completed 18 weeks of tx. UND at 4-6 weeks, UND at EOT, SVR 2, SVR 6 and SVR 12 on 6 May 2016.
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generic harvoni in india 7 years 3 months ago #1272

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James-Freeman-facebook wrote: Gilead's APIs are made in Jordan. The tablets are made in Ireland.


Jordan.

I think our hepatology doctors should be told that they are prescribing drugs made in a third world country. :dry:

generic harvoni in india 7 years 3 months ago #1273

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Yes, 100 000$ do not justify the high cost of production let say 1000$ in developed countries. They want to lower the cost to 300$ and this is possible only third world countries.

There is a lot of sofosbuvir and ledipasvir on www.alibaba.com/trade/search?fsb=y&Index...earchText=sofosbuvir

Simply we cant trust them
Male, Fibro F1. Geno 1b. ALT 67 before treatment Viral load 5 million. My huge viral load replicates in my nervous system as I suffer anxiety.
Started Twinvir 12/12/15.
Two weeks
ALT 17 at 2 weeks
Viral Load UND at 2 weeks
ALT 13.5 at 7 weeks EOT
ALT 10.5 at 15 weeks EOT
ALT 13 at 27 weeks EOT, VL UND, Cured

generic harvoni in india 7 years 3 months ago #1276

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hi,
Hope everyone is feeling well today,
I read this last night & thought it was relevant to this discussion, it's about big pharma, pricing, global access to HCV meds by Els Torreele, the Director of Access to Medicines, Public Health Program, Open Society Foundations.

Really worth reading & exploring the whole blog, a lot of good links in the body of that article, also If you would like to contribute a guest post on that blog, there is a contact details there.

from the blog:
"The unaffordability of medicines is no longer just a problem for poor people in developing countries—it is a global public health emergency. Excessive prices stand between North American and European patients and life-saving treatments. Strained health budgets lead states and insurers to delay or ration expensive medicines and increase out-of-pocket expenses. To get the drugs they need, patients must suffer serious “financial toxicity,” as cancer doctor Leonard Saltz poignantly puts it, or forego treatment altogether.
"

this is part 1:
blogs.plos.org/yoursay/2015/10/13/talkin...access-to-medicines/

part 2 is written by a Jessica Wapner, a freelance US science writer, activist, blogger, most enjoyable reading.
Here she explains how the big pharma works out their drug pricing strategy, like how do you get from $101 - the real cost of tx with Sofo to $50000 or more depending in which country you happened to live :

blogs.plos.org/yoursay/2015/10/15/talkin...-post-will-cost-you/
Geno 3, Fibro 8.7 pKA, tx experinced in 2005 - Peg/Riba, relapsed.
Started tx 1/12/2015 with Indian Sofo & Chinese Dac.
5 weeks result all normal, ALT 18 - down from ALT 73 at the start of tx.
5 weeks HCV PCR RNA - UND. - down from 2 ML
9 weeks HCV PCR RNA - UND.
The following user(s) said Thank You: emilio, Alsdad, Joy

generic harvoni in india 7 years 3 months ago #1277

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more about pricing:

from the Lancet article "Disparity in market prices for hepatitis C virus direct-acting drugs" :

The price per bottle of all originator DAAs varied substantially: for sofosbuvir it ranged from $300 (India, Pakistan) to $20 590 (Switzerland); for daclatasvir from $175 (Egypt) to $14 899 (Germany); for simeprevir from $241 (Egypt) to $14 865 (Australia); for ledipasvir-sofosbuvir from $400 (Egypt and Mongolia) to $24 890 (Germany); and for ombitasvir-paritaprevir-ritonavir (or 2D regimen) from $400 (Egypt) to $20 215 (Switzerland).


www.thelancet.com/journals/langlo/articl...(15)00156-4/fulltext
Geno 3, Fibro 8.7 pKA, tx experinced in 2005 - Peg/Riba, relapsed.
Started tx 1/12/2015 with Indian Sofo & Chinese Dac.
5 weeks result all normal, ALT 18 - down from ALT 73 at the start of tx.
5 weeks HCV PCR RNA - UND. - down from 2 ML
9 weeks HCV PCR RNA - UND.

generic harvoni in india 7 years 3 months ago #1278

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Jolie wrote: part 2 is written by a Jessica Wapner, a freelance US science writer, activist, blogger, most enjoyable reading.

blogs.plos.org/yoursay/2015/10/15/talkin...-post-will-cost-you/

Thanks Jolie, clever and funny article, worth a read. ;-)
NSW Australia. Genotype 1b 30+ years, F0-F1, VL 91,000 Feb 2015 (740,000 in 2010), Tx naive.
Ordered Sof/Dac from Buyers Club 21 Sept, received 14 Oct.
Virus UNDETECTED at 3 weeks AND 12 weeks (EOT) AND SVR4 AND SVR12 AND SVR24. :-)
A thousand thankyous to Dr James and the amazing FixHepC team.
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generic harvoni in india 7 years 3 months ago #1280

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Any way to take TWINVIR with DHL from Banglandeshi?
Male, Fibro F1. Geno 1b. ALT 67 before treatment Viral load 5 million. My huge viral load replicates in my nervous system as I suffer anxiety.
Started Twinvir 12/12/15.
Two weeks
ALT 17 at 2 weeks
Viral Load UND at 2 weeks
ALT 13.5 at 7 weeks EOT
ALT 10.5 at 15 weeks EOT
ALT 13 at 27 weeks EOT, VL UND, Cured

generic harvoni in india 7 years 3 months ago #1287

Enkel wrote: Any way to take TWINVIR with DHL from Banglandeshi?


Based on my recent own experience, no shipping companies in Bangladesh allowed to ship medicines. My contact inquired DHL and EMS, no one can do it. Well, my destination is China, so yours might be different.

generic harvoni in india 7 years 3 months ago #1322

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It has been my belief all along that the only country that will not bow to FDA and big pharma, (namely Gilead and others), is China, they're making plenty thank you very much and the cashed up baby boomer hepers will continue to access by the 100,000s. I'm a mesochem fan and will be forever grateful and will support and promote this supply chain.. Em
Geno 1b F2/3 snce early 80s. Treated in 2008_9 for 63 weeks on INF/Riba. Commence Sof/Dac on 6 October 2015 and completed 18 weeks of tx. UND at 4-6 weeks, UND at EOT, SVR 2, SVR 6 and SVR 12 on 6 May 2016.

generic harvoni in india 7 years 3 months ago #1532

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I thought we can now order Twinvir through buyers club.
Gen 1b, F1-F2. Naive.
Started Twinvir tx on 2 nd of December 2015 for 12 weeks.
Starting VL 400000, Alt 49/AST 44
1 week VL 29, ALT 44/AST 30.
4 weeks VL 12, ALT 33, Platelets 145, all other tests normal.
7 weeks VL Detected, ALT 28, all other normal
8 weeks UND, 12 week UND, 24 week SVR UND

generic harvoni in india 7 years 3 months ago #1535

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You can buy Twinvir if you're participating in The Redemption Trials as yet its
not for sale as part of The Buyers Club.

We are looking at how you can access Bangladesh directly without going through
The Buyers Club as there are many reps from Incepta, Beacon on the forum.

We are talking about this and I will post a thread shortly.
Sob/Dac from Oct 29 2015
Geno 1b
Fiberscan 9.9 Pre treatment
Fiberscan 7.4 week 10
VL 1.3 million pre treatment
Week 2.5 VL 96
Week 5.5 VL 17
Week 10 VL UD
SVR 3 UD
SVR 16 UD
Cured:
All liver functions in normal ranges.
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