www.empr.com/aasld-2015/sofosbuvir-based...osis/article/453762/

Maybe Dr. Freeman will explain this in plain English.

It says get rid of Hep C using drugs and the chemical mediator LOXL2 that causes fibrosis also goes away.

Which explains why we see regression of fibrosis at VL=0 and SVR.

If you are F4 you will probably never regain F0 and SVR, but you may well be less F'd than currently so regression back to F3 or F2.

Improvements in fibroscan scores post cure are well documented

fixhepc.com/forum/experts-corner/106-liv...ear-in-12-weeks.html

This explains the underlying pathophysiology.

I'm guessing you mean "never regain F0 at SVR"

"less F'd"