Data shows that a 12 week is just as accurate as a 24 week test.
But since you'll probably continue to wonder, you could save the money and have a Qualitative Viral Load test at 24 weeks instead of monthly liver enzymes. It gives you a negative or positive result but I believe it's cheaper than a Quantitative test. You can check with the lab in your country.
I love this part of the story. Congratulations Tweakmax!!
G1a probably early 1980's, Biopsy F1(2010), F2-F3(2015). VL 5+mill; 2+mill (2014) Tx naive. Accessed Sof/Led through Dr Freeman at GP2U and Buyers Club (lifesavers!!!)
Commenced tx 12/11/15. 9 wk: VL <15 Detected but LFT = Normal 12 week results: UND (Yay!) Due to slow response commenced Sof/Dac 4 Feb for 12 weeks. EOT @ 24 weeks 27 April 2016. (With thanks to Dr Freeman et al). SVR11 result: VL 1,950,000. It's back!
New tx 030916 (Viekira Pak, Solvadi, Ribavirin UND @ 111116. EOT 170217.
SVR12 and SVR 24
More than 9 out of 10 people will be cured using the current treatments for chronic hepatitis C virus infection. It is thrilling to be told that hepatitis C is no longer detectable in your blood. However, as much as we yearn for those words, sometimes it takes a long time to believe that hepatitis C is gone forever.
The medical term for a successful hepatitis C treatment outcome is sustained viral response (SVR). Undetectable HCV for 24 or more weeks after the end of treatment is an SVR24. Recently, many studies use the term SVR12, meaning that hepatitis C is undetectable for twelve or more weeks after the end of treatment. For those of us had a hard time believing that being viral-free for 24 weeks meant we were cured, then 12 weeks felt unbelievable. Can we trust this?
For most of us, yes. In the January 2015 Hepatology, Eric Yoshida and colleagues reported that there wasn't much difference between an SVR12 and SVR24 among hepatitis C patients who were treated with regimens using sofosbuvir. It didn't matter if interferon was part of the regimen. Analyzing data from studies using sofosbuvir, researchers looked at response rates for genotypes 1 through 6. There were a total of 327 genotypes 1, 4, 5, 6 (mostly genotype 1); 294 genotype 2s; and 250 genotype 3s.
Before presenting the results, there are a couple more terms that are important to understand:
•Relapse was defined as having a negative hepatitis C viral load (HCV RNA) at the end of treatment and subsequently having detectable HCV RNA above the LLOQ.
•In this case, LLOQ is lower limit of quantification, which is the lowest amount of virus that can be precisely counted.
SVR24 was achieved in 777 of 779 patients (99.7%) with SVR12. This means that everyone but two people who achieved an SVR12 had an SVR24. Here's the kicker: the two patients who didn't achieve an SVR 24 both had genotype 3 (both non-cirrhotic, treatment-experienced). Therefore, if you discarded the data for genotype 3 patients and counted everyone else, 100% of those who had an SVR12 had an SVR24. Using viral sequencing, these cases were relapses and not reinfection.
The life you save will be your own. START TREATMENT
Thank you received: 2254
Diagnosed in 2004, had HCV for all my adult life. Until 2016!!!!
Harvoni treatment, started 19 March 2016
4 week results Bilirubin 12 down from 14 pre treatment,
Gamma 25 down from 52, ALT 19 down from 63, AST 19 down from 47,
VL <15 down from a lazy 6 million or so
Bilirubin 10, GGT 18, ALT 19, AST 21, VL UND
12 Weeks post EOT
Bilirubin 11, GGT 16, ALT 22, AST 20, VL UND
Stop saying 'I wish' and start saying 'I will'. :)
Thank you received: 423
tweakmax wrote: My doc didn't order SVR24 VL test for me, only fibroscan. She seemed confident about the "cure".
You already had a happy SVR12 so I wish you a happy SVR24 and only UND!
We are waiting for you in the SV24 club!
HCV since I don't know. Diagnosed in 2010.
GT1b, F0/F1, VL 9M, ALT 44, AST 42, Tx naive,
started 12 wks Twinvir on 06.12.2015. Feeling great and grateful
Vindecat de HCV cu med. generice. Cured with generics HCV drugs.
Thank you received: 1594
Very interesting and pleasant news, thank you for sharing it.
Would you perhaps have a link to fb to post here or to send it to me via PM?
I believe it would be a nice information to put also on Twitter , especially that I've noticed there are not so many articles / information available in Romania about the HCV generic drugs.
In fiecare an HCV ucide peste 500000 oameni.Medicamentele generice pentru hepatita C functioneaza. Nu deveni statistica! Cauta pe Google “medicamente generice pentru hepatita C”.
HCV kills more than 500000 people every year. HCV generic drugs work. Don't become a statistic.
By sharing this Youtube video you might save someone’s life!
My TX: HEPCVIR-L[generic Harvoni]-India