So, as this study indicates, women that are in early menopause (whether natural or medically induced-grrrrr) have a much higher risk of non-response to pegylated interferon/ribavirin treatment.
This leads me to ponder whether this demographic would similarly be at a higher rate of non-response or alternatively, relapse, with the current DAA's. Perhaps the hormone imbalance may make it more difficult to eradicate the HCV?
There is a rapid progression of symtoms and disease in post menopausal women too.
I feel that the S/D treatment I am on only appeared to begin working after week 10, and foolishly did not adamantly request the hospital clinic test my viral load at week 4 or 8. I have just had my 12 week blood test done, and although according to the nurse 'there is no evidence to extend beyond 12', I am considering going beyond the extra 4 weeks I purchased from Kingswood Pharmacy.
Any input would be welcome as I grapple with this scenario and continue enjoying my present state of medicated nirvana.