TOPIC:

Can anyone give advice on the following; Avoiding fats while on daclatasvir? Am I ok to carry on with nicotine replacement while on tx and anything else to avoid? I am aware of avoiding grapefruit. thanks.

Hey Wilko
Seville oranges and I think, marmalade. The best of luck with your treatment, so pleased that you are finally sorted

Hi Wilko,

Couple of threads about things to avoid on Daclatasvir, just be aware in the second one that only the first four fruits are really a problem and garlic is probably since disproved but just don't eat several raw cloves at the same time as the Dac.

fixhepc.com/forum/drug-interactions/108-...ractions-cyp3a4.html

www.ganfyd.org/index.php?title=Inhibitors_of_CYP3A4

Regarding fats, there are some warnings about that going around but the only research I've seen involved taking it directly after a meal containing very high fat (from memory +30-40g?) in which case not as much was absorbed by your body. They suggested it wouldn't be a problem on normal diets. You can take Sof & Dac with or without food so if with then just make it a low fat meal. OTOH Ribavirin should be taken with some fat, in which case you may want to take It at a different time to the other meds.

Thanks Gaj, I'me taking my meds in the mornings, no riba required for me. So I can have double cream on me pud at evening meal!! Thats great , and I do like me gaalic in my cooking, usually at evening meal too. Cheers.

Great news they have Arrived at last..............

Hopefully, you have a easy time whilst on treatment I have my fingers crossed for you.

In no time you'll be joining us on the Undetected bench and soon after cured.

Good luck.