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TOPIC: frigtened by possible severe irreversible side effects
frigtened by possible severe irreversible side effects 5 years 7 months ago #21937
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Diagnosed September 2016. 1b ALAT in 40s. VL 460 000 Fibroscan 12.5 Start of treatment 18/10/16 Wk 2 VL 145 Wk 4 VL detected unquantifiable Wk 8 VL detected unquantifiable Wk 12 undetected week 30 after eot - undetected |
frigtened by possible severe irreversible side effects 5 years 7 months ago #21938
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Genotype 1A ALT 473 AST 226 Virus Load 3,119,030 Results as of May-2016 5 week viral load/undetected as of 12/02/2016 Liver Biopsy Results from Feb 2013 Portal/Periportal chronic inflammation and mild interface hepatitis (Grade 2) Focal Lobular chronic inflammation (Grade 1) Portal/Periportal fibrosis (stage 1-2 trichrome and reticulin stains utilized) Negative Iron stains. |
frigtened by possible severe irreversible side effects 5 years 7 months ago #21939
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GT1a Dec14 F2/8.7 VL 900000-2.5M Jan16 Hepcivir-L MonkMed/Redemption Baseline: VL 913575 Alt 76 Platelets low Wk2 VL1157 Alt 23 DET Wk 8 VL 32 Alt19 'In the slow lane' June16 Fibro 5.7 F0/1 LIF 1.5 Wk 11 VL<12 Alt 13 Det/Unq Extending tx 12 wks Mylan Sofo/Dac MonkMed Wk 14 VL <12 Det/Unq Wk 16 VL UNDETECTED Wk 22 + 4 Wks Sunprevir FixHepC Wk 24 UNDETECTED Alt 13 Wk 12 post tx SVR12 Wk 26 SVR24 Thank-you Tim, Dr Debasis @ MonkMed & Dr Freeman @ Fix HepC |
frigtened by possible severe irreversible side effects 5 years 7 months ago #21941
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Genotype 1A ALT 473 AST 226 Virus Load 3,119,030 Results as of May-2016 5 week viral load/undetected as of 12/02/2016 Liver Biopsy Results from Feb 2013 Portal/Periportal chronic inflammation and mild interface hepatitis (Grade 2) Focal Lobular chronic inflammation (Grade 1) Portal/Periportal fibrosis (stage 1-2 trichrome and reticulin stains utilized) Negative Iron stains. |
frigtened by possible severe irreversible side effects 5 years 7 months ago #21942
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GT3a 1990 Failed Inter 1998, comb in 2000. HCC 2012 Started 24/52 Sof/Dac 27th October 2015. 1. Bloods 2 October 2015: AST - 165 (20-40), ALT - 265 (5-40), GGT 189 (5-50) 2, Bloods 20 November 2015: ALT etc normal; VL 19 3. Bloods 8 January 2016: AST - 40, ALT - 59, GGT 48 VL RNA UND 4. EOT 12 April 2016 - blood tests: all is well, CT scan: okay 5. AFP 11 June 2016: 4 ref< 11 6. VL July 2016: DET 7. Oct16 start treat - June17 UND 8. Jun 18, lfts okay, platelets a bit low. |
frigtened by possible severe irreversible side effects 5 years 7 months ago #21943
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G3a since '78 - Dx '12 - F4 (2xHCC) 24wk Tx - PEG/Riba/Dac 2013 relapsed 24wk Tx - Generic Sof/Dac/Riba 2015/16 relapsed 16wk Tx - 12/01/17 -> 03/05/17 NS3/NS5a + Generic Sof SVR7 - 22/06/17 UND SRV12 - 27/07/17 UND SVR24 - 26/10/17 UND ![]() ![]() ![]() |
frigtened by possible severe irreversible side effects 5 years 7 months ago #21945
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Gen 1a Peg/inf/riba 2012(!) stop @ Wk 43 potassium low +issues (rlps week 4 post tx, VL120,000) scnds eg. adenomas. pre sof/led VL 240,000 Fibsc F0 Day 25 <30 Day 32 UND Week 10 UND EOT UND ALT11AST17GGT19 SVR4 UND ALT10 AST16 GGT13 SVR8 UND ALT <9 AST16 GGT15 SVR12 UND ALT14 AST19 GGT12 Bili 5 EOT +18 ALT13 AST20 GGT9 Bili 5 EOT +21 ALT11AST15 Cured SVR12 Dysplasia Adenomas RemvdAug '16 SVR24 UND ALT11AST16 ColonoscopyClear Nov17 LumpectomyClear ‘18 LithotripsyCytoscopyBiopsy 4/18 |
frigtened by possible severe irreversible side effects 5 years 7 months ago #21949
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GT1a Dec14 F2/8.7 VL 900000-2.5M Jan16 Hepcivir-L MonkMed/Redemption Baseline: VL 913575 Alt 76 Platelets low Wk2 VL1157 Alt 23 DET Wk 8 VL 32 Alt19 'In the slow lane' June16 Fibro 5.7 F0/1 LIF 1.5 Wk 11 VL<12 Alt 13 Det/Unq Extending tx 12 wks Mylan Sofo/Dac MonkMed Wk 14 VL <12 Det/Unq Wk 16 VL UNDETECTED Wk 22 + 4 Wks Sunprevir FixHepC Wk 24 UNDETECTED Alt 13 Wk 12 post tx SVR12 Wk 26 SVR24 Thank-you Tim, Dr Debasis @ MonkMed & Dr Freeman @ Fix HepC |
frigtened by possible severe irreversible side effects 5 years 7 months ago #21954
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Diagnosed September 2016. 1b ALAT in 40s. VL 460 000 Fibroscan 12.5 Start of treatment 18/10/16 Wk 2 VL 145 Wk 4 VL detected unquantifiable Wk 8 VL detected unquantifiable Wk 12 undetected week 30 after eot - undetected |
frigtened by possible severe irreversible side effects 5 years 7 months ago #21956
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Contracted HCV 1980's Geno Type 1a F3 ( doc says once treated I'll be F2 maybe F1) Meds shipped 6/17/2016 arrived early 7/2016 Viral count - 3,471,080 4 week quantitative bloods: August 17, 2016. I have been diagnosed as <15 (told undetected) 8 week quantitative bloods: September 14th. I have been diagnosed as <15 (told undetected) 11 week PCR RNA Qualitative bloods: September 26th 2016 - Undetected December 19th 2016: Cured! Viral count: zero!!! 2018 viral count: still zero! Cured! |
frigtened by possible severe irreversible side effects 5 years 7 months ago #21961
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GT1a Dec14 F2/8.7 VL 900000-2.5M Jan16 Hepcivir-L MonkMed/Redemption Baseline: VL 913575 Alt 76 Platelets low Wk2 VL1157 Alt 23 DET Wk 8 VL 32 Alt19 'In the slow lane' June16 Fibro 5.7 F0/1 LIF 1.5 Wk 11 VL<12 Alt 13 Det/Unq Extending tx 12 wks Mylan Sofo/Dac MonkMed Wk 14 VL <12 Det/Unq Wk 16 VL UNDETECTED Wk 22 + 4 Wks Sunprevir FixHepC Wk 24 UNDETECTED Alt 13 Wk 12 post tx SVR12 Wk 26 SVR24 Thank-you Tim, Dr Debasis @ MonkMed & Dr Freeman @ Fix HepC |
frigtened by possible severe irreversible side effects 5 years 7 months ago #21964
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45 yo male; UK; HCV since 1996; G4; F2-3 (fibroscan score 9.1); Null responder interferon/ribavirin 2008; 4/16 Harvoni 8 weeks; Pre-tx VL 2.1 million; week 4 VL 269; EOT UND; but... 6/16 Tx extended w/ generic sof/dac x 12 weeks due to concerns around my slow response to Harvoni. UND at end of 2nd round of treatment and EOT+4. |
frigtened by possible severe irreversible side effects 5 years 7 months ago #21969
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YMMV |
frigtened by possible severe irreversible side effects 5 years 7 months ago #21971
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Diagnosed September 2016. 1b ALAT in 40s. VL 460 000 Fibroscan 12.5 Start of treatment 18/10/16 Wk 2 VL 145 Wk 4 VL detected unquantifiable Wk 8 VL detected unquantifiable Wk 12 undetected week 30 after eot - undetected |
frigtened by possible severe irreversible side effects 5 years 7 months ago #21973
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GT1a Dec14 F2/8.7 VL 900000-2.5M Jan16 Hepcivir-L MonkMed/Redemption Baseline: VL 913575 Alt 76 Platelets low Wk2 VL1157 Alt 23 DET Wk 8 VL 32 Alt19 'In the slow lane' June16 Fibro 5.7 F0/1 LIF 1.5 Wk 11 VL<12 Alt 13 Det/Unq Extending tx 12 wks Mylan Sofo/Dac MonkMed Wk 14 VL <12 Det/Unq Wk 16 VL UNDETECTED Wk 22 + 4 Wks Sunprevir FixHepC Wk 24 UNDETECTED Alt 13 Wk 12 post tx SVR12 Wk 26 SVR24 Thank-you Tim, Dr Debasis @ MonkMed & Dr Freeman @ Fix HepC |
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