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TOPIC: Lactose Intolerance / E110

Lactose Intolerance / E110 2 years 2 months ago #9859

  • dointime
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Some of the meds coming in pill form contain lactose filler. If you are lactose intolerant then you may experience side effects from the lactose which you might mistake for side effects of the DAAs. Typically that would be some kind of intestinal discomfort but each person is different.

If your meds are being supplied by your normal source of meds, eg. the NHS, PBS, US Insurance, then I don't know what you are supposed to do about this. It's not like there is the choice of asking for a non-lactose version (or might there be?). For people who are paying for their own generics then their friendly compounding chemist would no doubt be able to forego the lactose on request.

While I am at it, some brand name Harvoni contains E110 which is a yellow dye. This dye can make your urine look darker than it already is. I looked it up and below are a list of side effects.
dt

www.ukfoodguide.net/e110.htm

"Side effects are urticaria (hives), rhinitis (runny nose), nasal congestion, allergies, hyperactivity, kidney tumors, chromosomal damage, abdominal pain, nausea and vomiting, indigestion, distaste for food; increased incidence of tumors in animals.
It appears to cause allergic and/or intolerance reactions, particularly amongst those with an aspirin intolerance.
Not recommended for consumption by children.
The Hyperactive Childrens Support Group belive that a link exists between this additive and hyperactive behavioural disorders in children.
Whilst being a commonly used colour in the UK its use is banned in Norway and Finland."
Last Edit: 2 years 2 months ago by dointime.
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Lactose Intolerance / E110 2 years 2 months ago #10533

  • Chejai
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Wow, DT that list of sx re E110 is pretty nasty! Although, I have to say reading any list of 'possible side effects' for products is always scary, they have to include all possibilities and it does depend on the amount you're ingesting.
Since my meds are white, I assume no E110 there (not Harvoni) but I think I read somewhere (Dr James) listed ingredients of meds from Buyers Club and I think Lactose is there. While many of my family members are Lactose Intolerant, I can have a very small amount before I'm affected, so meds would be very minimal.
QLD Australia ☀️
G3a HCV 35 yrs Tx naive
Started Sof/Dac 13/01/16

Dec '15
AST 70
ALT 89
GGT 124
Fibroscore 8.5
F1-F2
13 Feb'16 VL UND #woohoo!
AST 24
ALT 26
GGT 50H
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Lactose Intolerance / E110 2 years 2 months ago #10538

  • Gaj
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Hi Chejai,

If using the capsules via Buyers Club then my understanding is that there is no lactose or other incipient used, just pure Sof, Dac or Led. That is why the capsules aren't quite full.
G3a since '78 - Dx '12 - F4 (2xHCC)
24wk Tx - PEG/Riba/Dac 2013 relapsed
24wk Tx - Generic Sof/Dac/Riba 2015/16 relapsed
16wk Tx - 12/01/17 -> 03/05/17 NS3/NS5a + Generic Sof
SVR7 - 22/06/17 UND
SRV12 - 27/07/17 UND
SVR24 - 26/10/17 UND
:cheer: :cheer: :cheer:
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