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TOPIC: CYP3A4 Inhibitors and Daclatasvir - Fruits
CYP3A4 Inhibitors and Daclatasvir - Fruits 6 years 4 months ago #8547
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YMMV |
CYP3A4 Inhibitors and Daclatasvir - Fruits 6 years 4 months ago #8549
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M 61yo HCV+ ~ 30 yrs Gt1a F2 VL 223,000 ALT 54 AST 42 Tx start Sof/Dac 17Dec15. SVR4 at 7Apr16 ALT 22 AST 22 SVR12 at 9Jun16 ALT 23 AST 25 Melbourne, Australia |
CYP3A4 Inhibitors and Daclatasvir - Fruits 6 years 4 months ago #8604
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Infected in the 1980s sometime, diagnosed early 1990s, GT 3, F4, sof/dac commenced 13 Jan 2016 |
CYP3A4 Inhibitors and Daclatasvir - Fruits 6 years 4 months ago #9378
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Gen 3a 30yrs plus F3-F4 VL 14,000,000 Treatment Naive Sof/Dac 20.8.15 EOT 18.2.16 |
CYP3A4 Inhibitors and Daclatasvir - Fruits 6 years 4 months ago #9379
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Two time relapser. SVR 4 achieved 12/16 at last SVR 12 achieved 22/02/2017 The Bastard has been defeated ![]() ![]() ![]() GT 3 - about 28 yrs with HCV |
CYP3A4 Inhibitors and Daclatasvir - Fruits 6 years 4 months ago #9409
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YMMV |
CYP3A4 Inhibitors and Daclatasvir - Fruits 6 years 4 months ago #9445
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Gen 3a 30yrs plus F3-F4 VL 14,000,000 Treatment Naive Sof/Dac 20.8.15 EOT 18.2.16 |
CYP3A4 Inhibitors and Daclatasvir - Fruits 6 years 4 months ago #9448
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G3a since '78 - Dx '12 - F4 (2xHCC) 24wk Tx - PEG/Riba/Dac 2013 relapsed 24wk Tx - Generic Sof/Dac/Riba 2015/16 relapsed 16wk Tx - 12/01/17 -> 03/05/17 NS3/NS5a + Generic Sof SVR7 - 22/06/17 UND SRV12 - 27/07/17 UND SVR24 - 26/10/17 UND ![]() ![]() ![]() |
CYP3A4 Inhibitors and Daclatasvir - Fruits 6 years 3 months ago #9572
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QLD Australia ☀️ G3a HCV 35 yrs Tx naive Started Sof/Dac 13/01/16 Dec '15 AST 70 ALT 89 GGT 124 Fibroscore 8.5 F1-F2 13 Feb'16 VL UND ![]() AST 24 ALT 26 GGT 50H |
CYP3A4 Inhibitors and Daclatasvir - Fruits 6 years 2 months ago #12853
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G3a since '78 - Dx '12 - F4 (2xHCC) 24wk Tx - PEG/Riba/Dac 2013 relapsed 24wk Tx - Generic Sof/Dac/Riba 2015/16 relapsed 16wk Tx - 12/01/17 -> 03/05/17 NS3/NS5a + Generic Sof SVR7 - 22/06/17 UND SRV12 - 27/07/17 UND SVR24 - 26/10/17 UND ![]() ![]() ![]() |
CYP3A4 Inhibitors and Daclatasvir - Fruits 6 years 2 months ago #12855
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Genotype 3 30 years, 2x treatment interferon/ribavirin non responder. Cirrhosis 17 years. Fibroscan, decompensating, 40 down to 22 by 29/3/16- now down to 6.5, normal, no cirrhosis. Started Buyers Club Sof/Dac 14 Nov 15. SVR 12 29/0716 |
CYP3A4 Inhibitors and Daclatasvir - Fruits 6 years 2 months ago #12857
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YMMV |
CYP3A4 Inhibitors and Daclatasvir - Fruits 6 years 2 months ago #12867
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G3a since '78 - Dx '12 - F4 (2xHCC) 24wk Tx - PEG/Riba/Dac 2013 relapsed 24wk Tx - Generic Sof/Dac/Riba 2015/16 relapsed 16wk Tx - 12/01/17 -> 03/05/17 NS3/NS5a + Generic Sof SVR7 - 22/06/17 UND SRV12 - 27/07/17 UND SVR24 - 26/10/17 UND ![]() ![]() ![]() |
CYP3A4 Inhibitors and Daclatasvir - Fruits 6 years 2 months ago #12871
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YMMV |
CYP3A4 Inhibitors and Daclatasvir - Fruits 6 years 2 months ago #12890
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GT1a Dec14 F2/8.7 VL 900000-2.5M Jan16 Hepcivir-L MonkMed/Redemption Baseline: VL 913575 Alt 76 Platelets low Wk2 VL1157 Alt 23 DET Wk 8 VL 32 Alt19 'In the slow lane' June16 Fibro 5.7 F0/1 LIF 1.5 Wk 11 VL<12 Alt 13 Det/Unq Extending tx 12 wks Mylan Sofo/Dac MonkMed Wk 14 VL <12 Det/Unq Wk 16 VL UNDETECTED Wk 22 + 4 Wks Sunprevir FixHepC Wk 24 UNDETECTED Alt 13 Wk 12 post tx SVR12 Wk 26 SVR24 Thank-you Tim, Dr Debasis @ MonkMed & Dr Freeman @ Fix HepC |