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Thrush 6 years 3 months ago #17409

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Hi Price,

I'm not an expert in this field but I believe we need to be careful with our use of language when discussing these issues to ensure that people don't misunderstand the information. Below is a definition of PREbiotics as most scientists and the WHO would understand the word.

Prebiotics are defined as food substances that are undigested by humans but that stimulate beneficial microbial activities in the gut.


I am prepared to accept that what gets sold to the general public by some commercial enterprises may fit the description of "cell wall fragments from dead bacteria" but that is a problem with the world of marketing rather than an incorrect definition of prebiotics.
G3a since '78 - Dx '12 - F4 (2xHCC)
24wk Tx - PEG/Riba/Dac 2013 relapsed
24wk Tx - Generic Sof/Dac/Riba 2015/16 relapsed
16wk Tx - 12/01/17 -> 03/05/17 NS3/NS5a + Generic Sof
SVR7 - 22/06/17 UND
SRV12 - 27/07/17 UND
SVR24 - 26/10/17 UND
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Last edit: by Gaj.

Thrush 6 years 3 months ago #17422

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Hi Price

I’ve seemed to have stumbled onto the expert’s corner by mistake. I’ve been a naughty boy. Firstly, I derailed this thread by discussing yoghurt and then, accidently, started a debate on the semantics of what is, or isn’t, a prebiotic.

I’m a firm believer in the KISS principle (Keep it Simple Stupid). My intention is to offer simple advice to other HCV sufferers undertaking DAA treatment based on my experiences. My simple message is that if you have reflux problems, like I did, one way to resolve it is to adopt a high fibre diet made up of fresh vegetables, lean meat, and a premium yoghurt with live ABC cultures. This is something similar to what Monash Uni is espousing:

“The Monash Department of Gastroenterology is researching the impact of a 'high fibre and high natural prebiotic diet'. This diet is designed to establish a healthy balance of gut bacteria, needed for optimal health. While the diet is essentially a high fibre diet, it emphasises the consumption of foods that are high in 'prebiotic' fibres.”


Thanks for explaining what a leaky gut is. Luckily, I don’t have this problem. I’m sure it may help others who may be gluten intolerant or have other issues that may damage the intestinal lining and cause leaky gut. I realise that gut flora research is evolving quickly and is producing new and exciting revelations including the benefits of faecal transplants. In the interim, simply adopting a healthy diet and exercising regularly will help anyone currently undertaking DAA treatment.

1983: Hospitalised with Acute non-A, non-B Hepatitis after ICU blood transfusion 3mths earlier => HCV GT2
22/02/16: (pre-tmt) ALT 61, VL 2.48 IU/ml Hepascore 0.32 (F1/2), fatigue, brain fog, bloating (Treatment Naïve)
10/04/16: (Start tmt) Sofovir +DaclaHep (SOF + DCV) by Hetero Labs in India
09/05/16: ALT 34, VL: NOT Detected :cheer: :) , FBG 11.9 :huh:
17/6/16 FBG 5.7; PPBG (@14.22) 6.9 (@ 20.45) 7.1; BP 124/72
:) (Accu-Chek Mobile & Omron Auto BP Monitor) :)
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Thrush 6 years 3 months ago #17426

The two sllides on the links I posted come from some "expert" presentation, I forget which.

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Thrush 6 years 3 months ago #17427

If you have a fasting blood sugar of 11.6 then you're, at least, insulin resistant, which causes leaky gut. GI problems, like reflux, can also cause leaky gut.


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