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Sof/Vel and secret potion GS-9857 for relapse patients. 6 years 1 month ago #20274

fretboard
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Good news in the pipeline for patients who have unfortunately relapsed. High sustained virologic response achieved with sofosbuvir/velpatasvir and GS-9857, even in patients unsuccessfully treated with direct-acting antivirals The study showed that 99% of patients with HCV genotype 1, 2, 3, 4 and 6 who had previously received treatment, achieved SVR 12 weeks after treatment using this triple combination. The clinical trials are in phase 3, so it won't be long ppl. Just so you know, GS-9857 is a Gilead drug, no problem Mesochecm will have that formulation copied and ready to sell before you could say, what $94,000??? lol I don't know for certain, but I think the name of experimental compound GS-9857 is voxilaprevir, see the 2nd link. Hopefully this information helps someone, somehow. :cheer:

hepatitiscnewdrugs.blogspot.com/2016/04/...velpatasvir-and.html

www.evaluategroup.com/View/77895--1002-modData/product/gs-9857

clinicaltrials.gov/show/NCT02607735

G1a dx'd in 1992, Biopsy F2 VL 8mill +. Tried tx with Interferon/Riba, back in 2008 didn't last long it felt horribly ugly!! I stopped tx, after 5 weeks!!
Started tx 6/1/16 with Harvoni.
12 Month Labs= UND

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Last edit: by fretboard. Reason: Added another link.

Sof/Vel and secret potion GS-9857 for relapse patients. 6 years 1 month ago #20275

coral
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Thanks for posting Fretboard. Yes it is great news and it helps a lot #flower

G1a probably early 1980's, Biopsy F1(2010), F2-F3(2015). VL 5+mill; 2+mill (2014) Tx naive. Accessed Sof/Led through Dr Freeman at GP2U and Buyers Club (lifesavers!!!)
Commenced tx 12/11/15. 9 wk: VL <15 Detected but LFT = Normal 12 week results: UND (Yay!) Due to slow response commenced Sof/Dac 4 Feb for 12 weeks. EOT @ 24 weeks 27 April 2016. (With thanks to Dr Freeman et al). SVR11 result: VL 1,950,000. It's back!
New tx 030916 (Viekira Pak, Solvadi, Ribavirin UND @ 111116. EOT 170217.
SVR12 and SVR 24

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