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Taking oral medication for toenail fungus 7 years 9 months ago #22443
I have picked up a toe nail fungus and oral medication has been recommended. I am now undetected and liver function is normal, Is it alright to take medications that are hard on the liver. What tests should I apply to making this decision? Diagnosed in 2000, Genotype 1(b), no previous treatment, Viral Load 90,700, ALT 86, AST 56 (as of Novemeber 15, 2015) Fibroscan F0 Starting Redemption Sof/Led on February 2, 2016 Thanks to Greg Jeffries, Monkmed , FixHepC and Dr. Freeman Feb. 29 Week 5 of tx ALT 23 Undetected May 26 4 EOT ALT 25 AST 28 Didn't test for viral load. Will test is July at 12 weeks EOT August 1 Liver enzymes in normal range HCV UNDETECTED The following user(s) said Thank You: beaches | |
Taking oral medication for toenail fungus 7 years 9 months ago #22448
The oral antifungals are all a bit toxic. That is because fungal cells are very like human cells and therefore very hard to target without some collateral damage. That said, these drugs are generally safe and severe liver toxicity is very rare. One option would be to try intensive topical treatment for a good 3 months plus and use oral treatment only if that fails YMMV | |
Taking oral medication for toenail fungus 7 years 9 months ago #22449
Thanks James. I will try that. Diagnosed in 2000, Genotype 1(b), no previous treatment, Viral Load 90,700, ALT 86, AST 56 (as of Novemeber 15, 2015) Fibroscan F0 Starting Redemption Sof/Led on February 2, 2016 Thanks to Greg Jeffries, Monkmed , FixHepC and Dr. Freeman Feb. 29 Week 5 of tx ALT 23 Undetected May 26 4 EOT ALT 25 AST 28 Didn't test for viral load. Will test is July at 12 weeks EOT August 1 Liver enzymes in normal range HCV UNDETECTED The following user(s) said Thank You: beaches | |
Taking oral medication for toenail fungus 7 years 9 months ago #22451
I have just started using a generic version of loceryl and I'm still alive. Can't comment on its efficacy yet, apparently you have to apply it once a week for 6 to 12 months Genotype 1a Diagnosed in 2004, had HCV for all my adult life. Until 2016!!!! Harvoni treatment, started 19 March 2016 4 week results Bilirubin 12 down from 14 pre treatment, Gamma 25 down from 52, ALT 19 down from 63, AST 19 down from 47, VL <15 down from a lazy 6 million or so EOT Results Bilirubin 10, GGT 18, ALT 19, AST 21, VL UND 12 Weeks post EOT Bilirubin 11, GGT 16, ALT 22, AST 20, VL UND Cured baby | |
Taking oral medication for toenail fungus 7 years 9 months ago #22452
Thanks. Are you taking the oral med? I don't think the topical poses much problem for the liver, but have been warned that oral medication may. I am going to try a tea tree application to see if that can help before hitting the heavy artillery. I'll keep you posted and thanks for the response. Diagnosed in 2000, Genotype 1(b), no previous treatment, Viral Load 90,700, ALT 86, AST 56 (as of Novemeber 15, 2015) Fibroscan F0 Starting Redemption Sof/Led on February 2, 2016 Thanks to Greg Jeffries, Monkmed , FixHepC and Dr. Freeman Feb. 29 Week 5 of tx ALT 23 Undetected May 26 4 EOT ALT 25 AST 28 Didn't test for viral load. Will test is July at 12 weeks EOT August 1 Liver enzymes in normal range HCV UNDETECTED | |
Taking oral medication for toenail fungus 7 years 9 months ago #22453
Thanks. Are you taking the oral med? I don't think the topical poses much problem for the liver, but have been warned that oral medication may. I am going to try a tea tree application to see if that can help before hitting the heavy artillery. I'll keep you posted and thanks for the response. Diagnosed in 2000, Genotype 1(b), no previous treatment, Viral Load 90,700, ALT 86, AST 56 (as of Novemeber 15, 2015) Fibroscan F0 Starting Redemption Sof/Led on February 2, 2016 Thanks to Greg Jeffries, Monkmed , FixHepC and Dr. Freeman Feb. 29 Week 5 of tx ALT 23 Undetected May 26 4 EOT ALT 25 AST 28 Didn't test for viral load. Will test is July at 12 weeks EOT August 1 Liver enzymes in normal range HCV UNDETECTED | |
Taking oral medication for toenail fungus 7 years 9 months ago #22454
Loceryl is a topical agent used once a week. The application time depends on speed of nail growth. What you expect to see is new health nail growing outwards. Once all the infected nail is gone (ie trimmed off) treat for a bit longer to be sure, but you can see it progressively growing out. YMMV The following user(s) said Thank You: beaches | |
Taking oral medication for toenail fungus 7 years 9 months ago #22455
I've tried tea tree and various similar things including Chinese herbal medicine but none of then worked for me. Genotype 1a Diagnosed in 2004, had HCV for all my adult life. Until 2016!!!! Harvoni treatment, started 19 March 2016 4 week results Bilirubin 12 down from 14 pre treatment, Gamma 25 down from 52, ALT 19 down from 63, AST 19 down from 47, VL <15 down from a lazy 6 million or so EOT Results Bilirubin 10, GGT 18, ALT 19, AST 21, VL UND 12 Weeks post EOT Bilirubin 11, GGT 16, ALT 22, AST 20, VL UND Cured baby | |
Taking oral medication for toenail fungus 7 years 8 months ago #22464
Tea tree oil has had great results with treating toe nail fungus. There are clinical trials on this. I too have toenail fungus and now that I'm cured of HCV I'm using tea tree oil.. Dab it on twice a day.. I've really reduced the area affected The following user(s) said Thank You: beaches | |
Taking oral medication for toenail fungus 7 years 8 months ago #22465
I'm glad it's working for you. I never had any luck with it but now I'm inspired to give it another go. Maybe now that my immune system is no longer overworked I'll have more success. Genotype 1a Diagnosed in 2004, had HCV for all my adult life. Until 2016!!!! Harvoni treatment, started 19 March 2016 4 week results Bilirubin 12 down from 14 pre treatment, Gamma 25 down from 52, ALT 19 down from 63, AST 19 down from 47, VL <15 down from a lazy 6 million or so EOT Results Bilirubin 10, GGT 18, ALT 19, AST 21, VL UND 12 Weeks post EOT Bilirubin 11, GGT 16, ALT 22, AST 20, VL UND Cured baby The following user(s) said Thank You: cdmazoff | |
Taking oral medication for toenail fungus 7 years 8 months ago #22485
I've tried the shot, but this stuff works. It takes as long as it takes for the nails to grow, but, with once daily tx, you will never have those nice, thick, yellow nails again. Once clear, keep treating before bedtime. The shit is insidious but it can't stand the Nonyx. The Kera makes them look nice until its gone. m This email address is being protected from spambots. You need JavaScript enabled to view it. forums.delphiforums.com/generichcvtx G 1a F-1 Started tx 10/23/15 (Meso sof & led) ALT 48 AST 28 v/l 1.6 mil 11/17/15 4 wk lab ALT 17 AST 16 <15 11/18/15 Started Harvoni 12/16/15 8 wk lab ALT: 15 AST: 13 V/l UND 1/14/16 Fin. Tx 7/07/16 UND SVR 24 | |
Taking oral medication for toenail fungus 7 years 8 months ago #22656
| I am a chiropodistodiatrist of over 15 years of experience and I have not found Loceryl (amorolfine) to work except for the mildest of surface infections. I have known people to persevere for years without success. Terbinafine on the other hand invariable works although it might take 8-12 month, in rare cases 18 months. If your GP worries about liver damage he can order liver function tests. |
Taking oral medication for toenail fungus 7 years 8 months ago #22661
| Hey Zsuzsi, Lovely to see you here and giving advise. Hope you are well. LG (Sent you a PM) x GT1a Dec14 F2/8.7 VL 900000-2.5M Jan16 Hepcivir-L MonkMed/Redemption Baseline: VL 913575 Alt 76 Platelets low Wk2 VL1157 Alt 23 DET Wk 8 VL 32 Alt19 'In the slow lane' June16 Fibro 5.7 F0/1 LIF 1.5 Wk 11 VL<12 Alt 13 Det/Unq Extending tx 12 wks Mylan Sofo/Dac MonkMed Wk 14 VL <12 Det/Unq Wk 16 VL UNDETECTED Wk 22 + 4 Wks Sunprevir FixHepC Wk 24 UNDETECTED Alt 13 Wk 12 post tx SVR12 Wk 26 SVR24 Thank-you Tim, Dr Debasis @ MonkMed & Dr Freeman @ Fix HepC |
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